8B8S
 
 | | Solution structure of tandem RRM1 and RRM2 domains of yeast NPL3 | | Descriptor: | Serine/arginine (SR)-type shuttling mRNA binding protein NPL3 | | Authors: | Kachariya, N, Sattler, M, Keil, P, Strasser, K. | | Deposit date: | 2022-10-04 | | Release date: | 2022-11-09 | | Last modified: | 2023-02-08 | | Method: | SOLUTION NMR, SOLUTION SCATTERING | | Cite: | Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA.
Nucleic Acids Res., 51, 2023
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4ED5
 | | Crystal structure of the two N-terminal RRM domains of HuR complexed with RNA | | Descriptor: | 1,2-ETHANEDIOL, 1-METHOXY-2-(2-METHOXYETHOXY)ETHANE, 5'-R(*A*UP*UP*UP*UP*UP*AP*UP*UP*UP*U)-3', ... | | Authors: | Wang, H, Zeng, F, Liu, Q, Niu, L, Teng, M, Li, X. | | Deposit date: | 2012-03-27 | | Release date: | 2012-05-23 | | Last modified: | 2024-03-20 | | Method: | X-RAY DIFFRACTION (2 Å) | | Cite: | The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding.
Acta Crystallogr.,Sect.D, 69, 2013
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1L3K
 | | UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1 | | Descriptor: | HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 | | Authors: | Vitali, J, Ding, J, Jiang, J, Zhang, Y, Krainer, A.R, Xu, R.-M. | | Deposit date: | 2002-02-27 | | Release date: | 2002-04-17 | | Last modified: | 2023-08-16 | | Method: | X-RAY DIFFRACTION (1.1 Å) | | Cite: | Correlated alternative side chain conformations in the RNA-recognition motif of heterogeneous nuclear ribonucleoprotein A1.
Nucleic Acids Res., 30, 2002
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4W90
 | | Crystal structure of Bacillus subtilis cyclic-di-AMP riboswitch ydaO | | Descriptor: | (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, MAGNESIUM ION, U1 small nuclear ribonucleoprotein A, ... | | Authors: | Jones, C.P, Ferre-D'Amare, A.R. | | Deposit date: | 2014-08-26 | | Release date: | 2014-10-15 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.118 Å) | | Cite: | Crystal structure of a c-di-AMP riboswitch reveals an internally pseudo-dimeric RNA.
Embo J., 33, 2014
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6TR0
 | | Solution structure of U2AF2 RRM1,2 | | Descriptor: | Splicing factor U2AF 65 kDa subunit | | Authors: | Kang, H.-S, Sattler, M. | | Deposit date: | 2019-12-17 | | Release date: | 2020-05-06 | | Last modified: | 2023-06-14 | | Method: | SOLUTION NMR | | Cite: | An autoinhibitory intramolecular interaction proof-reads RNA recognition by the essential splicing factor U2AF2.
Proc.Natl.Acad.Sci.USA, 117, 2020
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3G8S
 | | Crystal structure of the pre-cleaved Bacillus anthracis glmS ribozyme | | Descriptor: | GLMS RIBOZYME, MAGNESIUM ION, RNA (5'-R(*AP*(A2M)P*GP*CP*GP*CP*CP*AP*GP*AP*AP*CP*U)-3'), ... | | Authors: | Strobel, S.A, Cochrane, J.C, Lipchock, S.V, Smith, K.D. | | Deposit date: | 2009-02-12 | | Release date: | 2009-11-03 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3.1 Å) | | Cite: | Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme
Biochemistry, 48, 2009
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3G8T
 | | Crystal structure of the G33A mutant Bacillus anthracis glmS ribozyme bound to GlcN6P | | Descriptor: | 2-amino-2-deoxy-6-O-phosphono-alpha-D-glucopyranose, MAGNESIUM ION, RNA (5'-R(*AP*(A2M)P*GP*CP*GP*CP*CP*AP*GP*AP*AP*CP*U)-3'), ... | | Authors: | Strobel, S.A, Cochrane, J.C, Lipchock, S.V, Smith, K.D. | | Deposit date: | 2009-02-12 | | Release date: | 2009-11-03 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (3 Å) | | Cite: | Structural and chemical basis for glucosamine 6-phosphate binding and activation of the glmS ribozyme
Biochemistry, 48, 2009
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7JLY
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7LHX
 | | Human U1A protein with F37M and F77M mutations for improved phasing | | Descriptor: | ACETATE ION, BETA-MERCAPTOETHANOL, SODIUM ION, ... | | Authors: | Jenkins, J.L, Lippa, G.M, Wedekind, J.E. | | Deposit date: | 2021-01-26 | | Release date: | 2021-03-17 | | Last modified: | 2023-11-15 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Affinity and Structural Analysis of the U1A RNA Recognition Motif with Engineered Methionines to Improve Experimental Phasing
Crystals, 11, 2021
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4YUD
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1VC5
 | | Crystal Structure of the Wild Type Hepatitis Delta Virus Gemonic Ribozyme Precursor, in EDTA solution | | Descriptor: | Hepatitis Delta virus ribozyme, SODIUM ION, U1 small nuclear ribonucleoprotein A | | Authors: | Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A. | | Deposit date: | 2004-03-04 | | Release date: | 2004-05-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (3.4 Å) | | Cite: | A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
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1VBZ
 | | Crystal Structure of the Hepatitis Delta Virus Gemonic Ribozyme Precursor, with C75U mutaion, in Ba2+ solution | | Descriptor: | BARIUM ION, Hepatitis Delta virus ribozyme, U1 small nuclear ribonucleoprotein A | | Authors: | Ke, A, Zhou, K, Ding, F, Cate, J.H.D, Doudna, J.A. | | Deposit date: | 2004-03-03 | | Release date: | 2004-05-18 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.8 Å) | | Cite: | A Conformational Switch controls hepatitis delta virus ribozyme catalysis
NATURE, 429, 2004
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6NSX
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1UP1
 | | UP1, THE TWO RNA-RECOGNITION MOTIF DOMAIN OF HNRNP A1 | | Descriptor: | HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN A1 | | Authors: | Xu, R.-M, Jokhan, L, Cheng, X, Mayeda, A, Krainer, A.R. | | Deposit date: | 1997-03-12 | | Release date: | 1997-09-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Crystal structure of human UP1, the domain of hnRNP A1 that contains two RNA-recognition motifs.
Structure, 5, 1997
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6NTY
 | | 2.1 A resolution structure of the Musashi-2 (Msi2) RNA recognition motif 1 (RRM1) domain | | Descriptor: | PHOSPHATE ION, RNA-binding protein Musashi homolog 2 | | Authors: | Lovell, S, Kashipathy, M.M, Battaile, K.P, Lan, L, Xiaoqing, W, Cooper, A, Gao, F.P, Xu, L. | | Deposit date: | 2019-01-30 | | Release date: | 2019-10-23 | | Last modified: | 2023-10-11 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Crystal and solution structures of human oncoprotein Musashi-2 N-terminal RNA recognition motif 1.
Proteins, 88, 2020
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6NWW
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4IUF
 | | Crystal Structure of Human TDP-43 RRM1 Domain in Complex with a Single-stranded DNA | | Descriptor: | 5'-D(*GP*TP*TP*GP*(XUA)P*GP*CP*GP*T)-3', TAR DNA-binding protein 43 | | Authors: | Kuo, P.H, Doudeva, L.G, Wang, Y.T, Yang, W.Z, Yuan, H.S. | | Deposit date: | 2013-01-21 | | Release date: | 2014-01-29 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (2.752 Å) | | Cite: | The crystal structure of TDP-43 RRM1-DNA complex reveals the specific recognition for UG- and TG-rich nucleic acids.
Nucleic Acids Res., 42, 2014
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5D77
 | | Structure of Mip6 RRM3 Domain | | Descriptor: | CITRIC ACID, NITRATE ION, RNA-binding protein MIP6, ... | | Authors: | Mohamad, N, Bravo, J. | | Deposit date: | 2015-08-13 | | Release date: | 2016-08-17 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (1.3 Å) | | Cite: | Structure of Mip6 RRM3 domain at 1.3
To Be Published
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5DDP
 | | L-glutamine riboswitch bound with L-glutamine | | Descriptor: | GLUTAMINE, MAGNESIUM ION, RNA (61-MER), ... | | Authors: | Ren, A, Patel, D.J. | | Deposit date: | 2015-08-25 | | Release date: | 2015-12-23 | | Last modified: | 2024-03-06 | | Method: | X-RAY DIFFRACTION (2.302 Å) | | Cite: | Structural and Dynamic Basis for Low-Affinity, High-Selectivity Binding of L-Glutamine by the Glutamine Riboswitch.
Cell Rep, 13, 2015
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5CYJ
 | | X-ray structure of human RBPMS | | Descriptor: | RNA-binding protein with multiple splicing | | Authors: | Teplova, M, Farazi, T.A, Patel, D.J. | | Deposit date: | 2015-07-30 | | Release date: | 2015-09-30 | | Last modified: | 2019-12-25 | | Method: | X-RAY DIFFRACTION (1.79 Å) | | Cite: | Structural basis underlying CAC RNA recognition by the RRM domain of dimeric RNA-binding protein RBPMS.
Q. Rev. Biophys., 49, 2016
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6TZE
 | | Human CstF-64 RRM mutant - D50A | | Descriptor: | Cleavage stimulation factor subunit 2 | | Authors: | Latham, M.P, Masoumzadeh, E. | | Deposit date: | 2019-08-12 | | Release date: | 2020-08-19 | | Last modified: | 2024-05-01 | | Method: | SOLUTION NMR | | Cite: | A missense mutation in the CSTF2 gene that impairs the function of the RNA recognition motif and causes defects in 3' end processing is associated with intellectual disability in humans.
Nucleic Acids Res., 48, 2020
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1B7F
 | | SXL-LETHAL PROTEIN/RNA COMPLEX | | Descriptor: | PROTEIN (SXL-LETHAL PROTEIN), RNA (5'-R(P*GP*UP*UP*GP*UP*UP*UP*UP*UP*UP*UP*U)-3') | | Authors: | Handa, N, Nureki, O, Kurimoto, K, Kim, I, Sakamoto, H, Shimura, Y, Muto, Y, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 1999-01-23 | | Release date: | 1999-05-03 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Structural basis for recognition of the tra mRNA precursor by the Sex-lethal protein.
Nature, 398, 1999
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1AUD
 | | U1A-UTRRNA, NMR, 31 STRUCTURES | | Descriptor: | RNA 3UTR, U1A 102 | | Authors: | Allain, F.H.-T, Gubser, C.C, Howe, P.W.A, Nagai, K, Neuhaus, D, Varani, G. | | Deposit date: | 1997-08-22 | | Release date: | 1998-02-25 | | Last modified: | 2021-11-03 | | Method: | SOLUTION NMR | | Cite: | Structural basis of the RNA-binding specificity of human U1A protein.
EMBO J., 16, 1997
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4LJM
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4LMZ
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