Summary
| Title: | Crystal structure of thrombin in complex with a novel tetra-O-acetyl-glucopyranoside-conjugated potent inhibitor |
| Citation: | Belviso, B.D.,Caliandro, R.,de Candia, M.,Zaetta, G.,Lopopolo, G.,Incampo, F.,Colucci, M.,Altomare, C.D. How a beta-d-Glucoside Side Chain Enhances Binding Affinity to Thrombin of Inhibitors Bearing 2-Chlorothiophene as P1 Moiety: Crystallography, Fragment Deconstruction Study, and Evaluation of Antithrombotic Properties. J.Med.Chem., 57:8563-8575, 2014 PubMed: 25268757DOI: 10.1021/jm5010754 |
| Experimental method: | X-RAY DIFFRACTION (1.98 Å) |
| Deposition date: | 2013-12-12 |
| Release date: | 2014-01-15 |
| Obsoletion date: | 2017-12-13 |
Timeline
Downloads
| File format | File name (file size) | ||
| PDBx/mmCIF | 4nze.cif.gz Display(73.60 KB) 4nze.cif | ||
| PDBML | all | 4nze.xml.gz Display(98.17 KB) 4nze.xml | |
| PDB | pdb4nze.ent.gz Display(58.09 KB) pdb4nze.ent | ||
| Structure factors | r4nzesf.ent.gz Display(386.38 KB) r4nzesf.ent | ||
