Summary
Title: | P38 Alpha Kinase complexed with a Pyrazolo-Pyrimidine based inhibitor |
Citation: | Das, J.,Moquin, R.V.,Pitt, S.,Zhang, R.,Shen, D.R.,McIntyre, K.W.,Gillooly, K.,Doweyko, A.M.,Sack, J.S.,Zhang, H.,Kiefer, S.E.,Kish, K.,McKinnon, M.,Barrish, J.C.,Dodd, J.H.,Schieven, G.L.,Leftheris, K. Pyrazolo-pyrimidines: a novel heterocyclic scaffold for potent and selective p38 alpha inhibitors. Bioorg.Med.Chem.Lett., 18:2652-2657, 2008 PubMed: 18359226DOI: 10.1016/j.bmcl.2008.03.019 |
Experimental method: | X-RAY DIFFRACTION (2.15 Å) |
Deposition date: | 2008-03-04 |
Release date: | 2008-04-08 |
Obsoletion date: | 2010-03-02 |
Timeline
Downloads
File format | File name (file size) | ||
PDBx/mmCIF | 3cg2.cif.gz Display(76.96 KB) 3cg2.cif | ||
PDBML | all | 3cg2.xml.gz Display(101.31 KB) 3cg2.xml | |
PDB | pdb3cg2.ent.gz Display(61.04 KB) pdb3cg2.ent | ||
Structure factors | r3cg2sf.ent.gz Display(130.63 KB) r3cg2sf.ent |