8SGH

Cryo-EM structure of Karyopherin-beta2 bound to HNRNPH2 PY-NLS

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003723	molecular_function	RNA binding
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005929	cellular_component	cilium
A	0006606	biological_process	protein import into nucleus
A	0006886	biological_process	intracellular protein transport
A	0008139	molecular_function	nuclear localization sequence binding
A	0015031	biological_process	protein transport
A	0031267	molecular_function	small GTPase binding
A	0061608	molecular_function	nuclear import signal receptor activity
A	0070062	cellular_component	extracellular exosome
B	0003676	molecular_function	nucleic acid binding
B	0003723	molecular_function	RNA binding

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	SITE: Important for interaction with cargo nuclear localization signals => ECO:0000269|PubMed:24753571

Chain	Residue	Details
A	TRP468
A	TRP738

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