8QYU
Beta-cardiac myosin S1 fragment in the pre-powerstroke state complexed to Omecamtiv mecarbil
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003774 | molecular_function | cytoskeletal motor activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0016459 | cellular_component | myosin complex |
| A | 0051015 | molecular_function | actin filament binding |
| B | 0003774 | molecular_function | cytoskeletal motor activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0016459 | cellular_component | myosin complex |
| B | 0051015 | molecular_function | actin filament binding |
| G | 0005509 | molecular_function | calcium ion binding |
| G | 0016459 | cellular_component | myosin complex |
| G | 0016460 | cellular_component | myosin II complex |
| H | 0005509 | molecular_function | calcium ion binding |
| H | 0016459 | cellular_component | myosin complex |
| H | 0016460 | cellular_component | myosin II complex |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | MOD_RES: N,N,N-trimethylalanine => ECO:0000269|PubMed:3979397 |
| Chain | Residue | Details |
| G | ALA2 | |
| H | ALA2 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P16409 |
| Chain | Residue | Details |
| G | THR92 | |
| G | THR133 | |
| H | THR92 | |
| H | THR133 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P09542 |
| Chain | Residue | Details |
| G | THR131 | |
| H | THR131 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P16409 |
| Chain | Residue | Details |
| G | TYR134 | |
| H | TYR134 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P09542 |
| Chain | Residue | Details |
| G | SER183 | |
| H | SER183 |
