8FV8

E coli. CTP synthase in complex with dF-dCTP + ADP

This is a non-PDB format compatible entry.

Functional Information from GO Data

Chain	GOid	namespace	contents
AAA	0000287	molecular_function	magnesium ion binding
AAA	0003883	molecular_function	CTP synthase activity
AAA	0004359	molecular_function	glutaminase activity
AAA	0005524	molecular_function	ATP binding
AAA	0005737	cellular_component	cytoplasm
AAA	0005829	cellular_component	cytosol
AAA	0006221	biological_process	pyrimidine nucleotide biosynthetic process
AAA	0006241	biological_process	CTP biosynthetic process
AAA	0006541	biological_process	glutamine metabolic process
AAA	0016874	molecular_function	ligase activity
AAA	0019856	biological_process	pyrimidine nucleobase biosynthetic process
AAA	0032991	cellular_component	protein-containing complex
AAA	0042802	molecular_function	identical protein binding
AAA	0044210	biological_process	'de novo' CTP biosynthetic process
AAA	0046872	molecular_function	metal ion binding
AAA	0051289	biological_process	protein homotetramerization
AAA	0097268	cellular_component	cytoophidium
BBB	0000287	molecular_function	magnesium ion binding
BBB	0003883	molecular_function	CTP synthase activity
BBB	0004359	molecular_function	glutaminase activity
BBB	0005524	molecular_function	ATP binding
BBB	0005737	cellular_component	cytoplasm
BBB	0005829	cellular_component	cytosol
BBB	0006221	biological_process	pyrimidine nucleotide biosynthetic process
BBB	0006241	biological_process	CTP biosynthetic process
BBB	0006541	biological_process	glutamine metabolic process
BBB	0016874	molecular_function	ligase activity
BBB	0019856	biological_process	pyrimidine nucleobase biosynthetic process
BBB	0032991	cellular_component	protein-containing complex
BBB	0042802	molecular_function	identical protein binding
BBB	0044210	biological_process	'de novo' CTP biosynthetic process
BBB	0046872	molecular_function	metal ion binding
BBB	0051289	biological_process	protein homotetramerization
BBB	0097268	cellular_component	cytoophidium

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile; for glutamine hydrolysis => ECO:0000305|PubMed:11336655, ECO:0000305|PubMed:15157079

Chain	Residue	Details
AAA	CYS379
BBB	CYS379

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: ACT_SITE => ECO:0000305|PubMed:15157079

Chain	Residue	Details
AAA	HIS515
AAA	GLU517
BBB	HIS515
BBB	GLU517

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site_id	SWS_FT_FI3
Number of Residues	6
Details	BINDING: BINDING => ECO:0000305|PubMed:16216072

Chain	Residue	Details
AAA	SER14
AAA	LYS187
AAA	LYS223
BBB	SER14
BBB	LYS187
BBB	LYS223

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site_id	SWS_FT_FI4
Number of Residues	6
Details	BINDING: BINDING => ECO:0000305|PubMed:16216072, ECO:0007744|PDB:2AD5

Chain	Residue	Details
AAA	SER15
AAA	ASP147
AAA	LYS239
BBB	SER15
BBB	ASP147
BBB	LYS239

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site_id	SWS_FT_FI5
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:16216072, ECO:0007744|PDB:2AD5

Chain	Residue	Details
AAA	ASP72
AAA	GLU140
BBB	ASP72
BBB	GLU140

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site_id	SWS_FT_FI6
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_01227

Chain	Residue	Details
AAA	GLY352
AAA	LEU380
AAA	GLU403
AAA	ARG470
BBB	GLY352
BBB	LEU380
BBB	GLU403
BBB	ARG470

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