Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

8D4E

Asymmetric unit of AP-1, Arf1, Nef lattice on MHC-I lipopeptide incorporated wide(r) membrane tubes

This is a non-PDB format compatible entry.
Functional Information from GO Data
ChainGOidnamespacecontents
B0000139cellular_componentGolgi membrane
B0001822biological_processkidney development
B0005515molecular_functionprotein binding
B0005765cellular_componentlysosomal membrane
B0005769cellular_componentearly endosome
B0005794cellular_componentGolgi apparatus
B0005829cellular_componentcytosol
B0006886biological_processintracellular protein transport
B0007368biological_processdetermination of left/right symmetry
B0007507biological_processheart development
B0015031biological_processprotein transport
B0016020cellular_componentmembrane
B0016192biological_processvesicle-mediated transport
B0019901molecular_functionprotein kinase binding
B0030117cellular_componentmembrane coat
B0030121cellular_componentAP-1 adaptor complex
B0030131cellular_componentclathrin adaptor complex
B0030276molecular_functionclathrin binding
B0030659cellular_componentcytoplasmic vesicle membrane
B0030665cellular_componentclathrin-coated vesicle membrane
B0031410cellular_componentcytoplasmic vesicle
B0032588cellular_componenttrans-Golgi network membrane
B0043231cellular_componentintracellular membrane-bounded organelle
B0060155biological_processplatelet dense granule organization
B0110010biological_processbasolateral protein secretion
B1903232biological_processmelanosome assembly
C0000139cellular_componentGolgi membrane
C0000287molecular_functionmagnesium ion binding
C0002090biological_processregulation of receptor internalization
C0003723molecular_functionRNA binding
C0003924molecular_functionGTPase activity
C0005515molecular_functionprotein binding
C0005525molecular_functionGTP binding
C0005794cellular_componentGolgi apparatus
C0005829cellular_componentcytosol
C0005886cellular_componentplasma membrane
C0005925cellular_componentfocal adhesion
C0006878biological_processintracellular copper ion homeostasis
C0006886biological_processintracellular protein transport
C0012505cellular_componentendomembrane system
C0014069cellular_componentpostsynaptic density
C0015031biological_processprotein transport
C0016020cellular_componentmembrane
C0016192biological_processvesicle-mediated transport
C0016787molecular_functionhydrolase activity
C0019904molecular_functionprotein domain specific binding
C0030017cellular_componentsarcomere
C0031252cellular_componentcell leading edge
C0032991cellular_componentprotein-containing complex
C0034315biological_processregulation of Arp2/3 complex-mediated actin nucleation
C0043005cellular_componentneuron projection
C0045202cellular_componentsynapse
C0060292biological_processlong-term synaptic depression
C0070062cellular_componentextracellular exosome
C0097061biological_processdendritic spine organization
C0098586biological_processcellular response to virus
C1990386biological_processmitotic cleavage furrow ingression
G0006886biological_processintracellular protein transport
G0016192biological_processvesicle-mediated transport
G0030117cellular_componentmembrane coat
H0000139cellular_componentGolgi membrane
H0000287molecular_functionmagnesium ion binding
H0002090biological_processregulation of receptor internalization
H0003723molecular_functionRNA binding
H0003924molecular_functionGTPase activity
H0005515molecular_functionprotein binding
H0005525molecular_functionGTP binding
H0005794cellular_componentGolgi apparatus
H0005829cellular_componentcytosol
H0005886cellular_componentplasma membrane
H0005925cellular_componentfocal adhesion
H0006878biological_processintracellular copper ion homeostasis
H0006886biological_processintracellular protein transport
H0012505cellular_componentendomembrane system
H0014069cellular_componentpostsynaptic density
H0015031biological_processprotein transport
H0016020cellular_componentmembrane
H0016192biological_processvesicle-mediated transport
H0016787molecular_functionhydrolase activity
H0019904molecular_functionprotein domain specific binding
H0030017cellular_componentsarcomere
H0031252cellular_componentcell leading edge
H0032991cellular_componentprotein-containing complex
H0034315biological_processregulation of Arp2/3 complex-mediated actin nucleation
H0043005cellular_componentneuron projection
H0045202cellular_componentsynapse
H0060292biological_processlong-term synaptic depression
H0070062cellular_componentextracellular exosome
H0097061biological_processdendritic spine organization
H0098586biological_processcellular response to virus
H1990386biological_processmitotic cleavage furrow ingression
L0005102molecular_functionsignaling receptor binding
L0005515molecular_functionprotein binding
L0005525molecular_functionGTP binding
L0005576cellular_componentextracellular region
L0006915biological_processapoptotic process
L0016020cellular_componentmembrane
L0017124molecular_functionSH3 domain binding
L0019049biological_processvirus-mediated perturbation of host defense response
L0019058biological_processviral life cycle
L0019901molecular_functionprotein kinase binding
L0020002cellular_componenthost cell plasma membrane
L0031996molecular_functionthioesterase binding
L0033668biological_processsymbiont-mediated suppression of host apoptosis
L0039505biological_processsymbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class II
L0039521biological_processsuppression by virus of host autophagy
L0042288molecular_functionMHC class I protein binding
L0042609molecular_functionCD4 receptor binding
L0044177cellular_componenthost cell Golgi apparatus
L0044178cellular_componenthost cell Golgi membrane
L0044423cellular_componentvirion component
L0045225biological_processnegative regulation of CD4 production
L0046776biological_processsymbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I
L0050848biological_processregulation of calcium-mediated signaling
L0051117molecular_functionATPase binding
L0070206biological_processprotein trimerization
L0075528biological_processperturbation by virus of host immune response
M0005515molecular_functionprotein binding
M0005765cellular_componentlysosomal membrane
M0005769cellular_componentearly endosome
M0005794cellular_componentGolgi apparatus
M0005802cellular_componenttrans-Golgi network
M0005829cellular_componentcytosol
M0006886biological_processintracellular protein transport
M0015031biological_processprotein transport
M0016020cellular_componentmembrane
M0016192biological_processvesicle-mediated transport
M0030121cellular_componentAP-1 adaptor complex
M0030131cellular_componentclathrin adaptor complex
M0030136cellular_componentclathrin-coated vesicle
M0030665cellular_componentclathrin-coated vesicle membrane
M0031410cellular_componentcytoplasmic vesicle
M0032438biological_processmelanosome organization
M0032588cellular_componenttrans-Golgi network membrane
M0035615molecular_functionclathrin adaptor activity
M0035646biological_processendosome to melanosome transport
M0043231cellular_componentintracellular membrane-bounded organelle
M0045202cellular_componentsynapse
M0051649biological_processestablishment of localization in cell
M0060155biological_processplatelet dense granule organization
M1903232biological_processmelanosome assembly
N0005102molecular_functionsignaling receptor binding
N0005515molecular_functionprotein binding
N0005525molecular_functionGTP binding
N0005576cellular_componentextracellular region
N0006915biological_processapoptotic process
N0016020cellular_componentmembrane
N0017124molecular_functionSH3 domain binding
N0019049biological_processvirus-mediated perturbation of host defense response
N0019058biological_processviral life cycle
N0019901molecular_functionprotein kinase binding
N0020002cellular_componenthost cell plasma membrane
N0031996molecular_functionthioesterase binding
N0033668biological_processsymbiont-mediated suppression of host apoptosis
N0039505biological_processsymbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class II
N0039521biological_processsuppression by virus of host autophagy
N0042288molecular_functionMHC class I protein binding
N0042609molecular_functionCD4 receptor binding
N0044177cellular_componenthost cell Golgi apparatus
N0044178cellular_componenthost cell Golgi membrane
N0044423cellular_componentvirion component
N0045225biological_processnegative regulation of CD4 production
N0046776biological_processsymbiont-mediated suppression of host antigen processing and presentation of peptide antigen via MHC class I
N0050848biological_processregulation of calcium-mediated signaling
N0051117molecular_functionATPase binding
N0070206biological_processprotein trimerization
N0075528biological_processperturbation by virus of host immune response
S0000139cellular_componentGolgi membrane
S0005515molecular_functionprotein binding
S0005765cellular_componentlysosomal membrane
S0005769cellular_componentearly endosome
S0005794cellular_componentGolgi apparatus
S0005829cellular_componentcytosol
S0005905cellular_componentclathrin-coated pit
S0006605biological_processprotein targeting
S0006886biological_processintracellular protein transport
S0015031biological_processprotein transport
S0016192biological_processvesicle-mediated transport
S0030117cellular_componentmembrane coat
S0030121cellular_componentAP-1 adaptor complex
S0030659cellular_componentcytoplasmic vesicle membrane
S0031410cellular_componentcytoplasmic vesicle
S0032588cellular_componenttrans-Golgi network membrane
S0035615molecular_functionclathrin adaptor activity
S0043231cellular_componentintracellular membrane-bounded organelle
S0060155biological_processplatelet dense granule organization
S1903232biological_processmelanosome assembly
Y0006955biological_processimmune response
Y0019882biological_processantigen processing and presentation
Z0000139cellular_componentGolgi membrane
Z0000287molecular_functionmagnesium ion binding
Z0002090biological_processregulation of receptor internalization
Z0003723molecular_functionRNA binding
Z0003924molecular_functionGTPase activity
Z0005515molecular_functionprotein binding
Z0005525molecular_functionGTP binding
Z0005794cellular_componentGolgi apparatus
Z0005829cellular_componentcytosol
Z0005886cellular_componentplasma membrane
Z0005925cellular_componentfocal adhesion
Z0006878biological_processintracellular copper ion homeostasis
Z0006886biological_processintracellular protein transport
Z0012505cellular_componentendomembrane system
Z0014069cellular_componentpostsynaptic density
Z0015031biological_processprotein transport
Z0016020cellular_componentmembrane
Z0016192biological_processvesicle-mediated transport
Z0016787molecular_functionhydrolase activity
Z0019904molecular_functionprotein domain specific binding
Z0030017cellular_componentsarcomere
Z0031252cellular_componentcell leading edge
Z0032991cellular_componentprotein-containing complex
Z0034315biological_processregulation of Arp2/3 complex-mediated actin nucleation
Z0043005cellular_componentneuron projection
Z0045202cellular_componentsynapse
Z0060292biological_processlong-term synaptic depression
Z0070062cellular_componentextracellular exosome
Z0097061biological_processdendritic spine organization
Z0098586biological_processcellular response to virus
Z1990386biological_processmitotic cleavage furrow ingression
Functional Information from PROSITE/UniProt
site_idPS00990
Number of Residues21
DetailsCLAT_ADAPTOR_M_1 Clathrin adaptor complexes medium chain signature 1. VSWRse.GikYrkNeVFLDVIE
ChainResidueDetails
MVAL157-GLU177

site_idPS00991
Number of Residues15
DetailsCLAT_ADAPTOR_M_2 Clathrin adaptor complexes medium chain signature 2. IsFIPPdGeFeLmsY
ChainResidueDetails
MILE253-TYR267

site_idPS00989
Number of Residues11
DetailsCLAT_ADAPTOR_S Clathrin adaptor complexes small chain signature. LVYKryasLYF
ChainResidueDetails
SLEU57-PHE67

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N-acetylserine => ECO:0000250|UniProtKB:Q9BXS5
ChainResidueDetails
MSER2
YGLY349
YSER350
YSER352

site_idSWS_FT_FI2
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0007744|PubMed:17242355, ECO:0007744|PubMed:21183079
ChainResidueDetails
MTHR152
MTHR154
ZASN126

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:Q32Q06
ChainResidueDetails
MTHR223
YSER359
ZALA160

site_idSWS_FT_FI4
Number of Residues3
DetailsMOD_RES: N-acetylglycine; alternate => ECO:0007744|PubMed:19413330, ECO:0007744|PubMed:22223895
ChainResidueDetails
CGLY2
HGLY2
ZGLY2

site_idSWS_FT_FI5
Number of Residues3
DetailsLIPID: N-myristoyl glycine; alternate => ECO:0000269|PubMed:20213681, ECO:0000269|PubMed:23535599, ECO:0000269|PubMed:25255805, ECO:0000269|PubMed:25807930
ChainResidueDetails
CGLY2
HGLY2
ZGLY2

219869

PDB entries from 2024-05-15

PDB statisticsPDBj update infoContact PDBjnumon