8BSU
Crystal structure of the kainate receptor GluK3-H523A ligand binding domain in complex with kainate and the positive allosteric modulator BPAM344 at 2.9A resolution
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
A | 0016020 | cellular_component | membrane |
B | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
B | 0016020 | cellular_component | membrane |
C | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
C | 0016020 | cellular_component | membrane |
D | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
D | 0016020 | cellular_component | membrane |
E | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
E | 0016020 | cellular_component | membrane |
F | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
F | 0016020 | cellular_component | membrane |
G | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
G | 0016020 | cellular_component | membrane |
H | 0015276 | molecular_function | ligand-gated monoatomic ion channel activity |
H | 0016020 | cellular_component | membrane |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 24 |
Details | BINDING: BINDING => ECO:0000269|PubMed:21907808 |
Chain | Residue | Details |
A | THR92 | |
A | ARG97 | |
A | GLU191 | |
B | THR92 | |
B | ARG97 | |
B | GLU191 | |
C | THR92 | |
C | ARG97 | |
C | GLU191 | |
D | THR92 | |
D | ARG97 | |
D | GLU191 | |
E | THR92 | |
E | ARG97 | |
E | GLU191 | |
F | THR92 | |
F | ARG97 | |
F | GLU191 | |
G | THR92 | |
G | ARG97 | |
G | GLU191 | |
H | THR92 | |
H | ARG97 | |
H | GLU191 |
site_id | SWS_FT_FI2 |
Number of Residues | 8 |
Details | BINDING: |
Chain | Residue | Details |
A | GLY142 | |
B | GLY142 | |
C | GLY142 | |
D | GLY142 | |
E | GLY142 | |
F | GLY142 | |
G | GLY142 | |
H | GLY142 |
site_id | SWS_FT_FI3 |
Number of Residues | 16 |
Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
Chain | Residue | Details |
A | ASN5 | |
A | ASN204 | |
B | ASN5 | |
B | ASN204 | |
C | ASN5 | |
C | ASN204 | |
D | ASN5 | |
D | ASN204 | |
E | ASN5 | |
E | ASN204 | |
F | ASN5 | |
F | ASN204 | |
G | ASN5 | |
G | ASN204 | |
H | ASN5 | |
H | ASN204 |