8BEF

Cryo-EM structure of the Arabidopsis thaliana I+III2 supercomplex (CI membrane core)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005739	cellular_component	mitochondrion
A	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
A	0016020	cellular_component	membrane
A	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
A	0030964	cellular_component	NADH dehydrogenase complex
A	0031966	cellular_component	mitochondrial membrane
A	0055085	biological_process	transmembrane transport
A	0070469	cellular_component	respirasome
H	0003954	molecular_function	NADH dehydrogenase activity
H	0005739	cellular_component	mitochondrion
H	0005743	cellular_component	mitochondrial inner membrane
H	0005747	cellular_component	mitochondrial respiratory chain complex I
H	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
H	0009060	biological_process	aerobic respiration
H	0016020	cellular_component	membrane
H	0055085	biological_process	transmembrane transport
H	0070469	cellular_component	respirasome
J	0005739	cellular_component	mitochondrion
J	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
J	0016020	cellular_component	membrane
J	0031966	cellular_component	mitochondrial membrane
J	0055085	biological_process	transmembrane transport
J	0070469	cellular_component	respirasome
K	0005739	cellular_component	mitochondrion
K	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
K	0016020	cellular_component	membrane
K	0016651	molecular_function	oxidoreductase activity, acting on NAD(P)H
K	0030964	cellular_component	NADH dehydrogenase complex
K	0031966	cellular_component	mitochondrial membrane
K	0042773	biological_process	ATP synthesis coupled electron transport
K	0055085	biological_process	transmembrane transport
K	0070469	cellular_component	respirasome
L	0003954	molecular_function	NADH dehydrogenase activity
L	0005739	cellular_component	mitochondrion
L	0005743	cellular_component	mitochondrial inner membrane
L	0005747	cellular_component	mitochondrial respiratory chain complex I
L	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
L	0009536	cellular_component	plastid
L	0015990	biological_process	electron transport coupled proton transport
L	0042773	biological_process	ATP synthesis coupled electron transport
L	0070469	cellular_component	respirasome
M	0003954	molecular_function	NADH dehydrogenase activity
M	0005739	cellular_component	mitochondrion
M	0005743	cellular_component	mitochondrial inner membrane
M	0005747	cellular_component	mitochondrial respiratory chain complex I
M	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
M	0009060	biological_process	aerobic respiration
M	0009536	cellular_component	plastid
M	0015990	biological_process	electron transport coupled proton transport
M	0042773	biological_process	ATP synthesis coupled electron transport
M	0048039	molecular_function	ubiquinone binding
M	0070469	cellular_component	respirasome
N	0005739	cellular_component	mitochondrion
N	0005743	cellular_component	mitochondrial inner membrane
N	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
N	0009536	cellular_component	plastid
N	0042773	biological_process	ATP synthesis coupled electron transport
N	0055085	biological_process	transmembrane transport
N	0070469	cellular_component	respirasome
O	0005515	molecular_function	protein binding
O	0005739	cellular_component	mitochondrion
O	0005747	cellular_component	mitochondrial respiratory chain complex I
O	0005829	cellular_component	cytosol
O	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
O	0008137	molecular_function	NADH dehydrogenase (ubiquinone) activity
O	0051536	molecular_function	iron-sulfur cluster binding
O	0051537	molecular_function	2 iron, 2 sulfur cluster binding
O	0055085	biological_process	transmembrane transport
O	0140647	biological_process	P450-containing electron transport chain
X	0005739	cellular_component	mitochondrion
X	0005747	cellular_component	mitochondrial respiratory chain complex I
X	0005758	cellular_component	mitochondrial intermembrane space
X	0006120	biological_process	mitochondrial electron transport, NADH to ubiquinone
X	0009536	cellular_component	plastid
X	0070469	cellular_component	respirasome
Y	0005739	cellular_component	mitochondrion
Y	0005741	cellular_component	mitochondrial outer membrane
Y	0005743	cellular_component	mitochondrial inner membrane
Y	0005747	cellular_component	mitochondrial respiratory chain complex I
Y	0005829	cellular_component	cytosol
Y	0006811	biological_process	monoatomic ion transport
Y	0009507	cellular_component	chloroplast
Y	0009527	cellular_component	plastid outer membrane
Y	0009707	cellular_component	chloroplast outer membrane
Y	0015288	molecular_function	porin activity
Y	0042721	cellular_component	TIM22 mitochondrial import inner membrane insertion complex
Y	0042803	molecular_function	protein homodimerization activity
Y	0045039	biological_process	protein insertion into mitochondrial inner membrane
Y	0046930	cellular_component	pore complex
Y	0055085	biological_process	transmembrane transport
Z	0005576	cellular_component	extracellular region
Z	0005739	cellular_component	mitochondrion
Z	0005743	cellular_component	mitochondrial inner membrane
Z	0005747	cellular_component	mitochondrial respiratory chain complex I
Z	0009793	biological_process	embryo development ending in seed dormancy
Z	0009853	biological_process	photorespiration
Z	0031966	cellular_component	mitochondrial membrane
Z	0045271	cellular_component	respiratory chain complex I
Z	0070469	cellular_component	respirasome
a	0005739	cellular_component	mitochondrion
a	0005743	cellular_component	mitochondrial inner membrane
a	0005747	cellular_component	mitochondrial respiratory chain complex I
a	0070469	cellular_component	respirasome
b	0005739	cellular_component	mitochondrion
b	0005829	cellular_component	cytosol
d	0000325	cellular_component	plant-type vacuole
d	0005739	cellular_component	mitochondrion
d	0005747	cellular_component	mitochondrial respiratory chain complex I
d	0005829	cellular_component	cytosol
e	0005739	cellular_component	mitochondrion
e	0005743	cellular_component	mitochondrial inner membrane
e	0005747	cellular_component	mitochondrial respiratory chain complex I
e	0005758	cellular_component	mitochondrial intermembrane space
e	0005829	cellular_component	cytosol
e	0070469	cellular_component	respirasome
f	0005739	cellular_component	mitochondrion
f	0005747	cellular_component	mitochondrial respiratory chain complex I
f	0005829	cellular_component	cytosol
f	0009853	biological_process	photorespiration
f	0031966	cellular_component	mitochondrial membrane
f	0045271	cellular_component	respiratory chain complex I
i	0005739	cellular_component	mitochondrion
i	0005747	cellular_component	mitochondrial respiratory chain complex I
i	0009853	biological_process	photorespiration
i	0031966	cellular_component	mitochondrial membrane
i	0045271	cellular_component	respiratory chain complex I
v	0000325	cellular_component	plant-type vacuole
v	0005507	molecular_function	copper ion binding
v	0005730	cellular_component	nucleolus
v	0005739	cellular_component	mitochondrion
v	0005747	cellular_component	mitochondrial respiratory chain complex I
v	0005777	cellular_component	peroxisome
v	0009853	biological_process	photorespiration
v	0031966	cellular_component	mitochondrial membrane
v	0045271	cellular_component	respiratory chain complex I
x	0000325	cellular_component	plant-type vacuole
x	0005515	molecular_function	protein binding
x	0005739	cellular_component	mitochondrion
x	0005747	cellular_component	mitochondrial respiratory chain complex I
x	0005829	cellular_component	cytosol
x	0009651	biological_process	response to salt stress
x	0009737	biological_process	response to abscisic acid
x	0009853	biological_process	photorespiration
x	0010228	biological_process	vegetative to reproductive phase transition of meristem
x	0016020	cellular_component	membrane
x	0031966	cellular_component	mitochondrial membrane
x	0045271	cellular_component	respiratory chain complex I
x	0046872	molecular_function	metal ion binding
y	0004089	molecular_function	carbonate dehydratase activity
y	0005515	molecular_function	protein binding
y	0005634	cellular_component	nucleus
y	0005737	cellular_component	cytoplasm
y	0005739	cellular_component	mitochondrion
y	0005747	cellular_component	mitochondrial respiratory chain complex I
y	0009853	biological_process	photorespiration
y	0009901	biological_process	anther dehiscence
y	0016020	cellular_component	membrane
y	0016829	molecular_function	lyase activity
y	0031966	cellular_component	mitochondrial membrane
y	0042802	molecular_function	identical protein binding
y	0045271	cellular_component	respiratory chain complex I
y	0046872	molecular_function	metal ion binding
y	0070207	biological_process	protein homotrimerization
y	2000377	biological_process	regulation of reactive oxygen species metabolic process
z	0004089	molecular_function	carbonate dehydratase activity
z	0005634	cellular_component	nucleus
z	0005739	cellular_component	mitochondrion
z	0005747	cellular_component	mitochondrial respiratory chain complex I
z	0009853	biological_process	photorespiration
z	0016020	cellular_component	membrane
z	0016829	molecular_function	lyase activity
z	0031966	cellular_component	mitochondrial membrane
z	0045271	cellular_component	respiratory chain complex I
z	0046872	molecular_function	metal ion binding
z	0070207	biological_process	protein homotrimerization

Functional Information from PROSITE/UniProt

site_id	PS00667
Number of Residues	16
Details	COMPLEX1_ND1_1 Respiratory-chain NADH dehydrogenase subunit 1 signature 1. GLLQpLaDGLKLIlKE

Chain	Residue	Details
H	GLY47-GLU62

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site_id	PS00668
Number of Residues	14
Details	COMPLEX1_ND1_2 Respiratory-chain NADH dehydrogenase subunit 1 signature 2. PFDLPEAEaeLVa.G

Chain	Residue	Details
H	PRO202-GLY215

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	280
Details	TRANSMEM: Helical => ECO:0000255

Chain	Residue	Details
L	SER40-ARG60
L	PHE76-VAL96
L	PHE113-PHE133
L	ALA217-GLY237
L	LEU136-THR156
L	LEU3-LEU23
L	THR250-ALA270
L	LEU283-LEU303
L	LEU319-MET339
L	ASN340-SER360
L	PHE375-LEU395
L	ASN417-LEU437
L	ILE461-ALA481
L	GLY619-PHE639

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylmethionine => ECO:0007744|PubMed:22223895

Chain	Residue	Details
Y	MET1

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