7WGE
Human NLRP1 complexed with thioredoxin
Functional Information from GO Data
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00136 |
| Chain | Residue | Details |
| A | GLY334 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | SITE: (Microbial infection) Cleavage; by human rhinovirus 14 (HRV-14) Protease 3C => ECO:0000269|PubMed:33093214, ECO:0000269|PubMed:33410748 |
| Chain | Residue | Details |
| A | GLN130 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | SITE: (Microbial infection) Cleavage; by coronavirus SARS-CoV-2 proteinase nsp5 => ECO:0000269|PubMed:35594856 |
| Chain | Residue | Details |
| A | GLN333 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | MOD_RES: Phosphoserine; by MAPK11 and MAPK14 => ECO:0000269|PubMed:35857590 |
| Chain | Residue | Details |
| A | SER99 | |
| A | SER101 | |
| A | SER170 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by MAPK14 => ECO:0000269|PubMed:35857590 |
| Chain | Residue | Details |
| A | SER107 | |
| A | SER163 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by MAPK11, MAPK14 and MAP3K20 => ECO:0000269|PubMed:35857590 |
| Chain | Residue | Details |
| A | THR112 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphoserine; by MAP3K20 => ECO:0000269|PubMed:35857590 |
| Chain | Residue | Details |
| A | SER113 | |
| A | SER132 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 2 |
| Details | MOD_RES: Phosphothreonine; by MAP3K20 => ECO:0000269|PubMed:35857590 |
| Chain | Residue | Details |
| A | THR114 | |
| A | THR129 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by MAPK11 and MAPk14 => ECO:0000269|PubMed:35857590 |
| Chain | Residue | Details |
| A | SER168 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by MAPK11 => ECO:0000269|PubMed:35857590 |
| Chain | Residue | Details |
| A | SER173 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by MAPK11 => ECO:0000269|PubMed:35857590 |
| Chain | Residue | Details |
| A | THR178 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine; by MAPK11 and MAP3K20 => ECO:0000269|PubMed:35857590 |
| Chain | Residue | Details |
| A | SER179 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by MAPK11 and MAP3K20 => ECO:0000269|PubMed:35857590 |
| Chain | Residue | Details |
| A | THR180 |
