7RPX

Archaeal DNA ligase and heterotrimeric PCNA in complex with end-joined DNA

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003677	molecular_function	DNA binding
A	0006260	biological_process	DNA replication
A	0006272	biological_process	leading strand elongation
A	0006275	biological_process	regulation of DNA replication
A	0030337	molecular_function	DNA polymerase processivity factor activity
B	0003677	molecular_function	DNA binding
B	0006260	biological_process	DNA replication
B	0006272	biological_process	leading strand elongation
B	0006275	biological_process	regulation of DNA replication
B	0030337	molecular_function	DNA polymerase processivity factor activity
C	0003677	molecular_function	DNA binding
C	0006260	biological_process	DNA replication
C	0006272	biological_process	leading strand elongation
C	0006275	biological_process	regulation of DNA replication
C	0030337	molecular_function	DNA polymerase processivity factor activity
E	0003677	molecular_function	DNA binding
E	0003909	molecular_function	DNA ligase activity
E	0003910	molecular_function	DNA ligase (ATP) activity
E	0005524	molecular_function	ATP binding
E	0006260	biological_process	DNA replication
E	0006266	biological_process	DNA ligation
E	0006273	biological_process	lagging strand elongation
E	0006281	biological_process	DNA repair
E	0006310	biological_process	DNA recombination
E	0016874	molecular_function	ligase activity
E	0046872	molecular_function	metal ion binding
E	0051301	biological_process	cell division
E	0071897	biological_process	DNA biosynthetic process

Functional Information from PROSITE/UniProt

site_id	PS00333
Number of Residues	27
Details	DNA_LIGASE_A2 ATP-dependent DNA ligase signature 2. EGVMVKaigkdai.YQaga...RgwlwiKLK

Chain	Residue	Details
E	GLU409-LYS435

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site_id	PS00697
Number of Residues	9
Details	DNA_LIGASE_A1 ATP-dependent DNA ligase AMP-binding site. DYKYDGERA

Chain	Residue	Details
E	ASP258-ALA266

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site_id	PS01251
Number of Residues	24
Details	PCNA_1 Proliferating cell nuclear antigen signature 1. SVeLvALDrAHIsLIsVnLpremF

Chain	Residue	Details
B	GLY33-PHE56
C	SER33-PHE56

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: N6-AMP-lysine intermediate

Chain	Residue	Details
E	LYS260

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site_id	SWS_FT_FI2
Number of Residues	5
Details	BINDING:

Chain	Residue	Details
E	ASP258
E	ARG265
E	ARG280
E	ARG427
E	LYS433

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00407

Chain	Residue	Details
E	GLU310
E	PHE350

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