7LOV

Crystal structure of Clostridium difficile Toxin B (TcdB) glucosyltransferase in complex with UDP and noeuromycin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016757	molecular_function	glycosyltransferase activity
B	0016757	molecular_function	glycosyltransferase activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:16054646, ECO:0000269|PubMed:28433497, ECO:0000269|PubMed:31308519, ECO:0007744|PDB:2BVL, ECO:0007744|PDB:2BVM, ECO:0007744|PDB:5UQM, ECO:0007744|PDB:5UQN, ECO:0007744|PDB:6OQ7

Chain	Residue	Details
A	VAL101
A	SER269
A	SER518
B	VAL101
B	SER269
B	SER518

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site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269|PubMed:16054646, ECO:0000269|PubMed:28433497, ECO:0007744|PDB:2BVL, ECO:0007744|PDB:2BVM, ECO:0007744|PDB:5UQM, ECO:0007744|PDB:5UQN

Chain	Residue	Details
A	ASN139
B	ASN139

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site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000305|PubMed:31308519, ECO:0007744|PDB:6OQ5

Chain	Residue	Details
A	ASP286
B	ASP286

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site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:16054646, ECO:0000269|PubMed:28433497, ECO:0000305|PubMed:31308519, ECO:0007744|PDB:2BVL, ECO:0007744|PDB:5UQM, ECO:0007744|PDB:5UQN, ECO:0007744|PDB:5UQT, ECO:0007744|PDB:6OQ7

Chain	Residue	Details
A	ASP288
A	GLU515
B	ASP288
B	GLU515

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site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P16154

Chain	Residue	Details
A	GLU545
B	GLU545

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site_id	SWS_FT_FI6
Number of Residues	2
Details	SITE: Cleavage; by autolysis => ECO:0000269|PubMed:15632438

Chain	Residue	Details
A	LEU543
B	LEU543

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