7KEU

Cryo-EM structure of the Caspase-1-CARD:ASC-CARD octamer

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006954	biological_process	inflammatory response
A	0042981	biological_process	regulation of apoptotic process
A	0045087	biological_process	innate immune response
B	0006954	biological_process	inflammatory response
B	0042981	biological_process	regulation of apoptotic process
B	0045087	biological_process	innate immune response
C	0006954	biological_process	inflammatory response
C	0042981	biological_process	regulation of apoptotic process
C	0045087	biological_process	innate immune response
D	0006954	biological_process	inflammatory response
D	0042981	biological_process	regulation of apoptotic process
D	0045087	biological_process	innate immune response
E	0042981	biological_process	regulation of apoptotic process
F	0042981	biological_process	regulation of apoptotic process
G	0042981	biological_process	regulation of apoptotic process
H	0042981	biological_process	regulation of apoptotic process

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25847972

Chain	Residue	Details
A	LYS174
B	LYS174
C	LYS174
D	LYS174

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Catalytic Information from CSA

site_id	MCSA1
Number of Residues
Details	M-CSA 718

Chain

Residue

Details

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site_id	MCSA2
Number of Residues
Details	M-CSA 718

Chain

Residue

Details

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site_id	MCSA3
Number of Residues
Details	M-CSA 718

Chain

Residue

Details

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site_id	MCSA4
Number of Residues
Details	M-CSA 718

Chain

Residue

Details

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