7DYG
Histone lysine demethylase 4D (KDM4D) in complex with the inhibitor 2-(1H-pyrazol-3-yl)isonicotinic acid
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000250|UniProtKB:B2RXH2 |
| Chain | Residue | Details |
| A | TYR136 | |
| A | LYS245 | |
| A | ASN202 | |
| A | LYS210 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00538, ECO:0000305|PubMed:26741168 |
| Chain | Residue | Details |
| A | HIS192 | |
| A | GLU194 | |
| A | HIS280 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0007744|PDB:5F5A, ECO:0007744|PDB:5F5C |
| Chain | Residue | Details |
| A | HIS244 | |
| A | CYS310 | |
| A | CYS312 | |
| A | CYS238 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | MOD_RES: PolyADP-ribosyl glutamic acid => ECO:0000269|PubMed:23102699 |
| Chain | Residue | Details |
| A | GLU26 | |
| A | GLU27 |
