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7D35

Human LC8 bound to ebola virus VP35(67-76)

Functional Information from GO Data
ChainGOidnamespacecontents
A0000776cellular_componentkinetochore
A0004857molecular_functionenzyme inhibitor activity
A0005515molecular_functionprotein binding
A0005634cellular_componentnucleus
A0005694cellular_componentchromosome
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005813cellular_componentcentrosome
A0005829cellular_componentcytosol
A0005856cellular_componentcytoskeleton
A0005868cellular_componentcytoplasmic dynein complex
A0005874cellular_componentmicrotubule
A0005875cellular_componentmicrotubule associated complex
A0005886cellular_componentplasma membrane
A0005929cellular_componentcilium
A0006915biological_processapoptotic process
A0006974biological_processDNA damage response
A0007017biological_processmicrotubule-based process
A0007286biological_processspermatid development
A0008180cellular_componentCOP9 signalosome
A0015630cellular_componentmicrotubule cytoskeleton
A0016020cellular_componentmembrane
A0019899molecular_functionenzyme binding
A0021762biological_processsubstantia nigra development
A0030141cellular_componentsecretory granule
A0030235molecular_functionnitric-oxide synthase regulator activity
A0030286cellular_componentdynein complex
A0035721biological_processintraciliary retrograde transport
A0035774biological_processpositive regulation of insulin secretion involved in cellular response to glucose stimulus
A0035861cellular_componentsite of double-strand break
A0036487molecular_functionnitric-oxide synthase inhibitor activity
A0042326biological_processnegative regulation of phosphorylation
A0042802molecular_functionidentical protein binding
A0044458biological_processmotile cilium assembly
A0044877molecular_functionprotein-containing complex binding
A0045019biological_processnegative regulation of nitric oxide biosynthetic process
A0045505molecular_functiondynein intermediate chain binding
A0060703molecular_functiondeoxyribonuclease inhibitor activity
A0070821cellular_componenttertiary granule membrane
A0072686cellular_componentmitotic spindle
A0097110molecular_functionscaffold protein binding
A0097542cellular_componentciliary tip
A0101003cellular_componentficolin-1-rich granule membrane
A0110027biological_processnegative regulation of DNA strand resection involved in replication fork processing
A1904115cellular_componentaxon cytoplasm
Functional Information from PROSITE/UniProt
site_idPS01239
Number of Residues15
DetailsDYNEIN_LIGHT_1 Dynein light chain type 1 signature. HcIvGRnFGSyVTHE
ChainResidueDetails
AHIS55-GLU69

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: N6-acetyllysine => ECO:0007744|PubMed:19608861
ChainResidueDetails
ALYS36

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000269|PubMed:15193260
ChainResidueDetails
ASER88

site_idSWS_FT_FI3
Number of Residues2
DetailsCROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733
ChainResidueDetails
ALYS43

219869

PDB entries from 2024-05-15

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