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6W4P

CaMKII alpha-30 Cryo-EM reconstruction - Class B

Functional Information from GO Data
ChainGOidnamespacecontents
A0000082biological_processG1/S transition of mitotic cell cycle
A0002931biological_processresponse to ischemia
A0004672molecular_functionprotein kinase activity
A0004674molecular_functionprotein serine/threonine kinase activity
A0004683molecular_functioncalmodulin-dependent protein kinase activity
A0005515molecular_functionprotein binding
A0005516molecular_functioncalmodulin binding
A0005524molecular_functionATP binding
A0005634cellular_componentnucleus
A0005654cellular_componentnucleoplasm
A0005737cellular_componentcytoplasm
A0005739cellular_componentmitochondrion
A0005829cellular_componentcytosol
A0005954cellular_componentcalcium- and calmodulin-dependent protein kinase complex
A0006468biological_processprotein phosphorylation
A0006816biological_processcalcium ion transport
A0010666biological_processpositive regulation of cardiac muscle cell apoptotic process
A0014069cellular_componentpostsynaptic density
A0016301molecular_functionkinase activity
A0018105biological_processpeptidyl-serine phosphorylation
A0030425cellular_componentdendrite
A0030666cellular_componentendocytic vesicle membrane
A0035254molecular_functionglutamate receptor binding
A0035458biological_processcellular response to interferon-beta
A0038166biological_processangiotensin-activated signaling pathway
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0042995cellular_componentcell projection
A0043005cellular_componentneuron projection
A0043197cellular_componentdendritic spine
A0043226cellular_componentorganelle
A0045202cellular_componentsynapse
A0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
A0046777biological_processprotein autophosphorylation
A0046872molecular_functionmetal ion binding
A0046928biological_processregulation of neurotransmitter secretion
A0048168biological_processregulation of neuronal synaptic plasticity
A0051092biological_processpositive regulation of NF-kappaB transcription factor activity
A0051346biological_processnegative regulation of hydrolase activity
A0051928biological_processpositive regulation of calcium ion transport
A0060996biological_processdendritic spine development
A0071346biological_processcellular response to type II interferon
A0106310molecular_functionprotein serine kinase activity
A1902108biological_processregulation of mitochondrial membrane permeability involved in apoptotic process
A1990443biological_processpeptidyl-threonine autophosphorylation
A2000124biological_processregulation of endocannabinoid signaling pathway
A2001222biological_processregulation of neuron migration
B0000082biological_processG1/S transition of mitotic cell cycle
B0002931biological_processresponse to ischemia
B0004672molecular_functionprotein kinase activity
B0004674molecular_functionprotein serine/threonine kinase activity
B0004683molecular_functioncalmodulin-dependent protein kinase activity
B0005515molecular_functionprotein binding
B0005516molecular_functioncalmodulin binding
B0005524molecular_functionATP binding
B0005634cellular_componentnucleus
B0005654cellular_componentnucleoplasm
B0005737cellular_componentcytoplasm
B0005739cellular_componentmitochondrion
B0005829cellular_componentcytosol
B0005954cellular_componentcalcium- and calmodulin-dependent protein kinase complex
B0006468biological_processprotein phosphorylation
B0006816biological_processcalcium ion transport
B0010666biological_processpositive regulation of cardiac muscle cell apoptotic process
B0014069cellular_componentpostsynaptic density
B0016301molecular_functionkinase activity
B0018105biological_processpeptidyl-serine phosphorylation
B0030425cellular_componentdendrite
B0030666cellular_componentendocytic vesicle membrane
B0035254molecular_functionglutamate receptor binding
B0035458biological_processcellular response to interferon-beta
B0038166biological_processangiotensin-activated signaling pathway
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0042995cellular_componentcell projection
B0043005cellular_componentneuron projection
B0043197cellular_componentdendritic spine
B0043226cellular_componentorganelle
B0045202cellular_componentsynapse
B0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
B0046777biological_processprotein autophosphorylation
B0046872molecular_functionmetal ion binding
B0046928biological_processregulation of neurotransmitter secretion
B0048168biological_processregulation of neuronal synaptic plasticity
B0051092biological_processpositive regulation of NF-kappaB transcription factor activity
B0051346biological_processnegative regulation of hydrolase activity
B0051928biological_processpositive regulation of calcium ion transport
B0060996biological_processdendritic spine development
B0071346biological_processcellular response to type II interferon
B0106310molecular_functionprotein serine kinase activity
B1902108biological_processregulation of mitochondrial membrane permeability involved in apoptotic process
B1990443biological_processpeptidyl-threonine autophosphorylation
B2000124biological_processregulation of endocannabinoid signaling pathway
B2001222biological_processregulation of neuron migration
C0000082biological_processG1/S transition of mitotic cell cycle
C0002931biological_processresponse to ischemia
C0004672molecular_functionprotein kinase activity
C0004674molecular_functionprotein serine/threonine kinase activity
C0004683molecular_functioncalmodulin-dependent protein kinase activity
C0005515molecular_functionprotein binding
C0005516molecular_functioncalmodulin binding
C0005524molecular_functionATP binding
C0005634cellular_componentnucleus
C0005654cellular_componentnucleoplasm
C0005737cellular_componentcytoplasm
C0005739cellular_componentmitochondrion
C0005829cellular_componentcytosol
C0005954cellular_componentcalcium- and calmodulin-dependent protein kinase complex
C0006468biological_processprotein phosphorylation
C0006816biological_processcalcium ion transport
C0010666biological_processpositive regulation of cardiac muscle cell apoptotic process
C0014069cellular_componentpostsynaptic density
C0016301molecular_functionkinase activity
C0018105biological_processpeptidyl-serine phosphorylation
C0030425cellular_componentdendrite
C0030666cellular_componentendocytic vesicle membrane
C0035254molecular_functionglutamate receptor binding
C0035458biological_processcellular response to interferon-beta
C0038166biological_processangiotensin-activated signaling pathway
C0042802molecular_functionidentical protein binding
C0042803molecular_functionprotein homodimerization activity
C0042995cellular_componentcell projection
C0043005cellular_componentneuron projection
C0043197cellular_componentdendritic spine
C0043226cellular_componentorganelle
C0045202cellular_componentsynapse
C0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
C0046777biological_processprotein autophosphorylation
C0046872molecular_functionmetal ion binding
C0046928biological_processregulation of neurotransmitter secretion
C0048168biological_processregulation of neuronal synaptic plasticity
C0051092biological_processpositive regulation of NF-kappaB transcription factor activity
C0051346biological_processnegative regulation of hydrolase activity
C0051928biological_processpositive regulation of calcium ion transport
C0060996biological_processdendritic spine development
C0071346biological_processcellular response to type II interferon
C0106310molecular_functionprotein serine kinase activity
C1902108biological_processregulation of mitochondrial membrane permeability involved in apoptotic process
C1990443biological_processpeptidyl-threonine autophosphorylation
C2000124biological_processregulation of endocannabinoid signaling pathway
C2001222biological_processregulation of neuron migration
D0000082biological_processG1/S transition of mitotic cell cycle
D0002931biological_processresponse to ischemia
D0004672molecular_functionprotein kinase activity
D0004674molecular_functionprotein serine/threonine kinase activity
D0004683molecular_functioncalmodulin-dependent protein kinase activity
D0005515molecular_functionprotein binding
D0005516molecular_functioncalmodulin binding
D0005524molecular_functionATP binding
D0005634cellular_componentnucleus
D0005654cellular_componentnucleoplasm
D0005737cellular_componentcytoplasm
D0005739cellular_componentmitochondrion
D0005829cellular_componentcytosol
D0005954cellular_componentcalcium- and calmodulin-dependent protein kinase complex
D0006468biological_processprotein phosphorylation
D0006816biological_processcalcium ion transport
D0010666biological_processpositive regulation of cardiac muscle cell apoptotic process
D0014069cellular_componentpostsynaptic density
D0016301molecular_functionkinase activity
D0018105biological_processpeptidyl-serine phosphorylation
D0030425cellular_componentdendrite
D0030666cellular_componentendocytic vesicle membrane
D0035254molecular_functionglutamate receptor binding
D0035458biological_processcellular response to interferon-beta
D0038166biological_processangiotensin-activated signaling pathway
D0042802molecular_functionidentical protein binding
D0042803molecular_functionprotein homodimerization activity
D0042995cellular_componentcell projection
D0043005cellular_componentneuron projection
D0043197cellular_componentdendritic spine
D0043226cellular_componentorganelle
D0045202cellular_componentsynapse
D0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
D0046777biological_processprotein autophosphorylation
D0046872molecular_functionmetal ion binding
D0046928biological_processregulation of neurotransmitter secretion
D0048168biological_processregulation of neuronal synaptic plasticity
D0051092biological_processpositive regulation of NF-kappaB transcription factor activity
D0051346biological_processnegative regulation of hydrolase activity
D0051928biological_processpositive regulation of calcium ion transport
D0060996biological_processdendritic spine development
D0071346biological_processcellular response to type II interferon
D0106310molecular_functionprotein serine kinase activity
D1902108biological_processregulation of mitochondrial membrane permeability involved in apoptotic process
D1990443biological_processpeptidyl-threonine autophosphorylation
D2000124biological_processregulation of endocannabinoid signaling pathway
D2001222biological_processregulation of neuron migration
E0000082biological_processG1/S transition of mitotic cell cycle
E0002931biological_processresponse to ischemia
E0004672molecular_functionprotein kinase activity
E0004674molecular_functionprotein serine/threonine kinase activity
E0004683molecular_functioncalmodulin-dependent protein kinase activity
E0005515molecular_functionprotein binding
E0005516molecular_functioncalmodulin binding
E0005524molecular_functionATP binding
E0005634cellular_componentnucleus
E0005654cellular_componentnucleoplasm
E0005737cellular_componentcytoplasm
E0005739cellular_componentmitochondrion
E0005829cellular_componentcytosol
E0005954cellular_componentcalcium- and calmodulin-dependent protein kinase complex
E0006468biological_processprotein phosphorylation
E0006816biological_processcalcium ion transport
E0010666biological_processpositive regulation of cardiac muscle cell apoptotic process
E0014069cellular_componentpostsynaptic density
E0016301molecular_functionkinase activity
E0018105biological_processpeptidyl-serine phosphorylation
E0030425cellular_componentdendrite
E0030666cellular_componentendocytic vesicle membrane
E0035254molecular_functionglutamate receptor binding
E0035458biological_processcellular response to interferon-beta
E0038166biological_processangiotensin-activated signaling pathway
E0042802molecular_functionidentical protein binding
E0042803molecular_functionprotein homodimerization activity
E0042995cellular_componentcell projection
E0043005cellular_componentneuron projection
E0043197cellular_componentdendritic spine
E0043226cellular_componentorganelle
E0045202cellular_componentsynapse
E0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
E0046777biological_processprotein autophosphorylation
E0046872molecular_functionmetal ion binding
E0046928biological_processregulation of neurotransmitter secretion
E0048168biological_processregulation of neuronal synaptic plasticity
E0051092biological_processpositive regulation of NF-kappaB transcription factor activity
E0051346biological_processnegative regulation of hydrolase activity
E0051928biological_processpositive regulation of calcium ion transport
E0060996biological_processdendritic spine development
E0071346biological_processcellular response to type II interferon
E0106310molecular_functionprotein serine kinase activity
E1902108biological_processregulation of mitochondrial membrane permeability involved in apoptotic process
E1990443biological_processpeptidyl-threonine autophosphorylation
E2000124biological_processregulation of endocannabinoid signaling pathway
E2001222biological_processregulation of neuron migration
F0000082biological_processG1/S transition of mitotic cell cycle
F0002931biological_processresponse to ischemia
F0004672molecular_functionprotein kinase activity
F0004674molecular_functionprotein serine/threonine kinase activity
F0004683molecular_functioncalmodulin-dependent protein kinase activity
F0005515molecular_functionprotein binding
F0005516molecular_functioncalmodulin binding
F0005524molecular_functionATP binding
F0005634cellular_componentnucleus
F0005654cellular_componentnucleoplasm
F0005737cellular_componentcytoplasm
F0005739cellular_componentmitochondrion
F0005829cellular_componentcytosol
F0005954cellular_componentcalcium- and calmodulin-dependent protein kinase complex
F0006468biological_processprotein phosphorylation
F0006816biological_processcalcium ion transport
F0010666biological_processpositive regulation of cardiac muscle cell apoptotic process
F0014069cellular_componentpostsynaptic density
F0016301molecular_functionkinase activity
F0018105biological_processpeptidyl-serine phosphorylation
F0030425cellular_componentdendrite
F0030666cellular_componentendocytic vesicle membrane
F0035254molecular_functionglutamate receptor binding
F0035458biological_processcellular response to interferon-beta
F0038166biological_processangiotensin-activated signaling pathway
F0042802molecular_functionidentical protein binding
F0042803molecular_functionprotein homodimerization activity
F0042995cellular_componentcell projection
F0043005cellular_componentneuron projection
F0043197cellular_componentdendritic spine
F0043226cellular_componentorganelle
F0045202cellular_componentsynapse
F0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
F0046777biological_processprotein autophosphorylation
F0046872molecular_functionmetal ion binding
F0046928biological_processregulation of neurotransmitter secretion
F0048168biological_processregulation of neuronal synaptic plasticity
F0051092biological_processpositive regulation of NF-kappaB transcription factor activity
F0051346biological_processnegative regulation of hydrolase activity
F0051928biological_processpositive regulation of calcium ion transport
F0060996biological_processdendritic spine development
F0071346biological_processcellular response to type II interferon
F0106310molecular_functionprotein serine kinase activity
F1902108biological_processregulation of mitochondrial membrane permeability involved in apoptotic process
F1990443biological_processpeptidyl-threonine autophosphorylation
F2000124biological_processregulation of endocannabinoid signaling pathway
F2001222biological_processregulation of neuron migration
G0000082biological_processG1/S transition of mitotic cell cycle
G0002931biological_processresponse to ischemia
G0004672molecular_functionprotein kinase activity
G0004674molecular_functionprotein serine/threonine kinase activity
G0004683molecular_functioncalmodulin-dependent protein kinase activity
G0005515molecular_functionprotein binding
G0005516molecular_functioncalmodulin binding
G0005524molecular_functionATP binding
G0005634cellular_componentnucleus
G0005654cellular_componentnucleoplasm
G0005737cellular_componentcytoplasm
G0005739cellular_componentmitochondrion
G0005829cellular_componentcytosol
G0005954cellular_componentcalcium- and calmodulin-dependent protein kinase complex
G0006468biological_processprotein phosphorylation
G0006816biological_processcalcium ion transport
G0010666biological_processpositive regulation of cardiac muscle cell apoptotic process
G0014069cellular_componentpostsynaptic density
G0016301molecular_functionkinase activity
G0018105biological_processpeptidyl-serine phosphorylation
G0030425cellular_componentdendrite
G0030666cellular_componentendocytic vesicle membrane
G0035254molecular_functionglutamate receptor binding
G0035458biological_processcellular response to interferon-beta
G0038166biological_processangiotensin-activated signaling pathway
G0042802molecular_functionidentical protein binding
G0042803molecular_functionprotein homodimerization activity
G0042995cellular_componentcell projection
G0043005cellular_componentneuron projection
G0043197cellular_componentdendritic spine
G0043226cellular_componentorganelle
G0045202cellular_componentsynapse
G0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
G0046777biological_processprotein autophosphorylation
G0046872molecular_functionmetal ion binding
G0046928biological_processregulation of neurotransmitter secretion
G0048168biological_processregulation of neuronal synaptic plasticity
G0051092biological_processpositive regulation of NF-kappaB transcription factor activity
G0051346biological_processnegative regulation of hydrolase activity
G0051928biological_processpositive regulation of calcium ion transport
G0060996biological_processdendritic spine development
G0071346biological_processcellular response to type II interferon
G0106310molecular_functionprotein serine kinase activity
G1902108biological_processregulation of mitochondrial membrane permeability involved in apoptotic process
G1990443biological_processpeptidyl-threonine autophosphorylation
G2000124biological_processregulation of endocannabinoid signaling pathway
G2001222biological_processregulation of neuron migration
H0000082biological_processG1/S transition of mitotic cell cycle
H0002931biological_processresponse to ischemia
H0004672molecular_functionprotein kinase activity
H0004674molecular_functionprotein serine/threonine kinase activity
H0004683molecular_functioncalmodulin-dependent protein kinase activity
H0005515molecular_functionprotein binding
H0005516molecular_functioncalmodulin binding
H0005524molecular_functionATP binding
H0005634cellular_componentnucleus
H0005654cellular_componentnucleoplasm
H0005737cellular_componentcytoplasm
H0005739cellular_componentmitochondrion
H0005829cellular_componentcytosol
H0005954cellular_componentcalcium- and calmodulin-dependent protein kinase complex
H0006468biological_processprotein phosphorylation
H0006816biological_processcalcium ion transport
H0010666biological_processpositive regulation of cardiac muscle cell apoptotic process
H0014069cellular_componentpostsynaptic density
H0016301molecular_functionkinase activity
H0018105biological_processpeptidyl-serine phosphorylation
H0030425cellular_componentdendrite
H0030666cellular_componentendocytic vesicle membrane
H0035254molecular_functionglutamate receptor binding
H0035458biological_processcellular response to interferon-beta
H0038166biological_processangiotensin-activated signaling pathway
H0042802molecular_functionidentical protein binding
H0042803molecular_functionprotein homodimerization activity
H0042995cellular_componentcell projection
H0043005cellular_componentneuron projection
H0043197cellular_componentdendritic spine
H0043226cellular_componentorganelle
H0045202cellular_componentsynapse
H0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
H0046777biological_processprotein autophosphorylation
H0046872molecular_functionmetal ion binding
H0046928biological_processregulation of neurotransmitter secretion
H0048168biological_processregulation of neuronal synaptic plasticity
H0051092biological_processpositive regulation of NF-kappaB transcription factor activity
H0051346biological_processnegative regulation of hydrolase activity
H0051928biological_processpositive regulation of calcium ion transport
H0060996biological_processdendritic spine development
H0071346biological_processcellular response to type II interferon
H0106310molecular_functionprotein serine kinase activity
H1902108biological_processregulation of mitochondrial membrane permeability involved in apoptotic process
H1990443biological_processpeptidyl-threonine autophosphorylation
H2000124biological_processregulation of endocannabinoid signaling pathway
H2001222biological_processregulation of neuron migration
I0000082biological_processG1/S transition of mitotic cell cycle
I0002931biological_processresponse to ischemia
I0004672molecular_functionprotein kinase activity
I0004674molecular_functionprotein serine/threonine kinase activity
I0004683molecular_functioncalmodulin-dependent protein kinase activity
I0005515molecular_functionprotein binding
I0005516molecular_functioncalmodulin binding
I0005524molecular_functionATP binding
I0005634cellular_componentnucleus
I0005654cellular_componentnucleoplasm
I0005737cellular_componentcytoplasm
I0005739cellular_componentmitochondrion
I0005829cellular_componentcytosol
I0005954cellular_componentcalcium- and calmodulin-dependent protein kinase complex
I0006468biological_processprotein phosphorylation
I0006816biological_processcalcium ion transport
I0010666biological_processpositive regulation of cardiac muscle cell apoptotic process
I0014069cellular_componentpostsynaptic density
I0016301molecular_functionkinase activity
I0018105biological_processpeptidyl-serine phosphorylation
I0030425cellular_componentdendrite
I0030666cellular_componentendocytic vesicle membrane
I0035254molecular_functionglutamate receptor binding
I0035458biological_processcellular response to interferon-beta
I0038166biological_processangiotensin-activated signaling pathway
I0042802molecular_functionidentical protein binding
I0042803molecular_functionprotein homodimerization activity
I0042995cellular_componentcell projection
I0043005cellular_componentneuron projection
I0043197cellular_componentdendritic spine
I0043226cellular_componentorganelle
I0045202cellular_componentsynapse
I0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
I0046777biological_processprotein autophosphorylation
I0046872molecular_functionmetal ion binding
I0046928biological_processregulation of neurotransmitter secretion
I0048168biological_processregulation of neuronal synaptic plasticity
I0051092biological_processpositive regulation of NF-kappaB transcription factor activity
I0051346biological_processnegative regulation of hydrolase activity
I0051928biological_processpositive regulation of calcium ion transport
I0060996biological_processdendritic spine development
I0071346biological_processcellular response to type II interferon
I0106310molecular_functionprotein serine kinase activity
I1902108biological_processregulation of mitochondrial membrane permeability involved in apoptotic process
I1990443biological_processpeptidyl-threonine autophosphorylation
I2000124biological_processregulation of endocannabinoid signaling pathway
I2001222biological_processregulation of neuron migration
J0000082biological_processG1/S transition of mitotic cell cycle
J0002931biological_processresponse to ischemia
J0004672molecular_functionprotein kinase activity
J0004674molecular_functionprotein serine/threonine kinase activity
J0004683molecular_functioncalmodulin-dependent protein kinase activity
J0005515molecular_functionprotein binding
J0005516molecular_functioncalmodulin binding
J0005524molecular_functionATP binding
J0005634cellular_componentnucleus
J0005654cellular_componentnucleoplasm
J0005737cellular_componentcytoplasm
J0005739cellular_componentmitochondrion
J0005829cellular_componentcytosol
J0005954cellular_componentcalcium- and calmodulin-dependent protein kinase complex
J0006468biological_processprotein phosphorylation
J0006816biological_processcalcium ion transport
J0010666biological_processpositive regulation of cardiac muscle cell apoptotic process
J0014069cellular_componentpostsynaptic density
J0016301molecular_functionkinase activity
J0018105biological_processpeptidyl-serine phosphorylation
J0030425cellular_componentdendrite
J0030666cellular_componentendocytic vesicle membrane
J0035254molecular_functionglutamate receptor binding
J0035458biological_processcellular response to interferon-beta
J0038166biological_processangiotensin-activated signaling pathway
J0042802molecular_functionidentical protein binding
J0042803molecular_functionprotein homodimerization activity
J0042995cellular_componentcell projection
J0043005cellular_componentneuron projection
J0043197cellular_componentdendritic spine
J0043226cellular_componentorganelle
J0045202cellular_componentsynapse
J0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
J0046777biological_processprotein autophosphorylation
J0046872molecular_functionmetal ion binding
J0046928biological_processregulation of neurotransmitter secretion
J0048168biological_processregulation of neuronal synaptic plasticity
J0051092biological_processpositive regulation of NF-kappaB transcription factor activity
J0051346biological_processnegative regulation of hydrolase activity
J0051928biological_processpositive regulation of calcium ion transport
J0060996biological_processdendritic spine development
J0071346biological_processcellular response to type II interferon
J0106310molecular_functionprotein serine kinase activity
J1902108biological_processregulation of mitochondrial membrane permeability involved in apoptotic process
J1990443biological_processpeptidyl-threonine autophosphorylation
J2000124biological_processregulation of endocannabinoid signaling pathway
J2001222biological_processregulation of neuron migration
K0000082biological_processG1/S transition of mitotic cell cycle
K0002931biological_processresponse to ischemia
K0004672molecular_functionprotein kinase activity
K0004674molecular_functionprotein serine/threonine kinase activity
K0004683molecular_functioncalmodulin-dependent protein kinase activity
K0005515molecular_functionprotein binding
K0005516molecular_functioncalmodulin binding
K0005524molecular_functionATP binding
K0005634cellular_componentnucleus
K0005654cellular_componentnucleoplasm
K0005737cellular_componentcytoplasm
K0005739cellular_componentmitochondrion
K0005829cellular_componentcytosol
K0005954cellular_componentcalcium- and calmodulin-dependent protein kinase complex
K0006468biological_processprotein phosphorylation
K0006816biological_processcalcium ion transport
K0010666biological_processpositive regulation of cardiac muscle cell apoptotic process
K0014069cellular_componentpostsynaptic density
K0016301molecular_functionkinase activity
K0018105biological_processpeptidyl-serine phosphorylation
K0030425cellular_componentdendrite
K0030666cellular_componentendocytic vesicle membrane
K0035254molecular_functionglutamate receptor binding
K0035458biological_processcellular response to interferon-beta
K0038166biological_processangiotensin-activated signaling pathway
K0042802molecular_functionidentical protein binding
K0042803molecular_functionprotein homodimerization activity
K0042995cellular_componentcell projection
K0043005cellular_componentneuron projection
K0043197cellular_componentdendritic spine
K0043226cellular_componentorganelle
K0045202cellular_componentsynapse
K0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
K0046777biological_processprotein autophosphorylation
K0046872molecular_functionmetal ion binding
K0046928biological_processregulation of neurotransmitter secretion
K0048168biological_processregulation of neuronal synaptic plasticity
K0051092biological_processpositive regulation of NF-kappaB transcription factor activity
K0051346biological_processnegative regulation of hydrolase activity
K0051928biological_processpositive regulation of calcium ion transport
K0060996biological_processdendritic spine development
K0071346biological_processcellular response to type II interferon
K0106310molecular_functionprotein serine kinase activity
K1902108biological_processregulation of mitochondrial membrane permeability involved in apoptotic process
K1990443biological_processpeptidyl-threonine autophosphorylation
K2000124biological_processregulation of endocannabinoid signaling pathway
K2001222biological_processregulation of neuron migration
L0000082biological_processG1/S transition of mitotic cell cycle
L0002931biological_processresponse to ischemia
L0004672molecular_functionprotein kinase activity
L0004674molecular_functionprotein serine/threonine kinase activity
L0004683molecular_functioncalmodulin-dependent protein kinase activity
L0005515molecular_functionprotein binding
L0005516molecular_functioncalmodulin binding
L0005524molecular_functionATP binding
L0005634cellular_componentnucleus
L0005654cellular_componentnucleoplasm
L0005737cellular_componentcytoplasm
L0005739cellular_componentmitochondrion
L0005829cellular_componentcytosol
L0005954cellular_componentcalcium- and calmodulin-dependent protein kinase complex
L0006468biological_processprotein phosphorylation
L0006816biological_processcalcium ion transport
L0010666biological_processpositive regulation of cardiac muscle cell apoptotic process
L0014069cellular_componentpostsynaptic density
L0016301molecular_functionkinase activity
L0018105biological_processpeptidyl-serine phosphorylation
L0030425cellular_componentdendrite
L0030666cellular_componentendocytic vesicle membrane
L0035254molecular_functionglutamate receptor binding
L0035458biological_processcellular response to interferon-beta
L0038166biological_processangiotensin-activated signaling pathway
L0042802molecular_functionidentical protein binding
L0042803molecular_functionprotein homodimerization activity
L0042995cellular_componentcell projection
L0043005cellular_componentneuron projection
L0043197cellular_componentdendritic spine
L0043226cellular_componentorganelle
L0045202cellular_componentsynapse
L0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
L0046777biological_processprotein autophosphorylation
L0046872molecular_functionmetal ion binding
L0046928biological_processregulation of neurotransmitter secretion
L0048168biological_processregulation of neuronal synaptic plasticity
L0051092biological_processpositive regulation of NF-kappaB transcription factor activity
L0051346biological_processnegative regulation of hydrolase activity
L0051928biological_processpositive regulation of calcium ion transport
L0060996biological_processdendritic spine development
L0071346biological_processcellular response to type II interferon
L0106310molecular_functionprotein serine kinase activity
L1902108biological_processregulation of mitochondrial membrane permeability involved in apoptotic process
L1990443biological_processpeptidyl-threonine autophosphorylation
L2000124biological_processregulation of endocannabinoid signaling pathway
L2001222biological_processregulation of neuron migration
M0000082biological_processG1/S transition of mitotic cell cycle
M0002931biological_processresponse to ischemia
M0004672molecular_functionprotein kinase activity
M0004674molecular_functionprotein serine/threonine kinase activity
M0004683molecular_functioncalmodulin-dependent protein kinase activity
M0005515molecular_functionprotein binding
M0005516molecular_functioncalmodulin binding
M0005524molecular_functionATP binding
M0005634cellular_componentnucleus
M0005654cellular_componentnucleoplasm
M0005737cellular_componentcytoplasm
M0005739cellular_componentmitochondrion
M0005829cellular_componentcytosol
M0005954cellular_componentcalcium- and calmodulin-dependent protein kinase complex
M0006468biological_processprotein phosphorylation
M0006816biological_processcalcium ion transport
M0010666biological_processpositive regulation of cardiac muscle cell apoptotic process
M0014069cellular_componentpostsynaptic density
M0016301molecular_functionkinase activity
M0018105biological_processpeptidyl-serine phosphorylation
M0030425cellular_componentdendrite
M0030666cellular_componentendocytic vesicle membrane
M0035254molecular_functionglutamate receptor binding
M0035458biological_processcellular response to interferon-beta
M0038166biological_processangiotensin-activated signaling pathway
M0042802molecular_functionidentical protein binding
M0042803molecular_functionprotein homodimerization activity
M0042995cellular_componentcell projection
M0043005cellular_componentneuron projection
M0043197cellular_componentdendritic spine
M0043226cellular_componentorganelle
M0045202cellular_componentsynapse
M0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
M0046777biological_processprotein autophosphorylation
M0046872molecular_functionmetal ion binding
M0046928biological_processregulation of neurotransmitter secretion
M0048168biological_processregulation of neuronal synaptic plasticity
M0051092biological_processpositive regulation of NF-kappaB transcription factor activity
M0051346biological_processnegative regulation of hydrolase activity
M0051928biological_processpositive regulation of calcium ion transport
M0060996biological_processdendritic spine development
M0071346biological_processcellular response to type II interferon
M0106310molecular_functionprotein serine kinase activity
M1902108biological_processregulation of mitochondrial membrane permeability involved in apoptotic process
M1990443biological_processpeptidyl-threonine autophosphorylation
M2000124biological_processregulation of endocannabinoid signaling pathway
M2001222biological_processregulation of neuron migration
Functional Information from PROSITE/UniProt
site_idPS00107
Number of Residues24
DetailsPROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGKGAFSVVRrCvkvlagqe..........YAAK
ChainResidueDetails
ALEU-309-LYS-286

site_idPS00108
Number of Residues13
DetailsPROTEIN_KINASE_ST Serine/Threonine protein kinases active-site signature. VvHrDLKpeNLLL
ChainResidueDetails
AVAL-197-LEU-185

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Proton acceptor => ECO:0000255|PROSITE-ProRule:PRU00159, ECO:0000255|PROSITE-ProRule:PRU10027
ChainResidueDetails
HASN127
BASP-208
CASP-203
DASP-205
EASP-207
FASP-208
GASP-193
IASP-208
JASP-203
KASP-205
LASP-207
MASP-208

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00159
ChainResidueDetails
GLEU-309
GLYS-286
ILEU-324
ILYS-301
JLEU-319
JLYS-296
KLEU-321
KLYS-298
LLEU-323
LLYS-300
MLEU-324
MLYS-301
BLEU-324
BLYS-301
CLEU-319
CLYS-296
DLEU-321
DLYS-298
ELEU-323
ELYS-300
FLEU-324
FLYS-301
HLEU13
HMET34

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Phosphotyrosine => ECO:0000250|UniProtKB:P11798
ChainResidueDetails
CTYR-325
DTYR-327
ETYR-329
FTYR-330
GTYR-315
ITYR-330
JTYR-325
KTYR-327
LTYR-329
MTYR-330
HTYR7
BTYR-330

site_idSWS_FT_FI4
Number of Residues1
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P11275
ChainResidueDetails
BSER-86
CSER-81
DSER-83
ESER-85
FSER-86
GSER-71
ISER-86
JSER-81
KSER-83
LSER-85
MSER-86
HSER249

site_idSWS_FT_FI5
Number of Residues1
DetailsMOD_RES: Phosphothreonine; by autocatalysis => ECO:0000250|UniProtKB:P11275
ChainResidueDetails
BTHR-57
CTHR-52
DTHR-54
ETHR-56
FTHR-57
GTHR-42
ITHR-57
JTHR-52
KTHR-54
LTHR-56
MTHR-57
HTHR278

site_idSWS_FT_FI6
Number of Residues4
DetailsMOD_RES: Phosphoserine => ECO:0000250|UniProtKB:P11798
ChainResidueDetails
DSER-10
DSER-9
DSER-7
DSER62
ESER-12
ESER-11
ESER-9
ESER60
FSER-13
FSER-12
FSER-10
FSER58
GSER2
GSER3
GSER5
GSER76
ISER-13
ISER-12
ISER-10
ISER60
JSER-8
JSER-7
JSER-5
JSER66
KSER-10
KSER-9
KSER-7
KSER62
LSER-12
LSER-11
LSER-9
LSER60
MSER-13
MSER-12
MSER-10
MSER58
HSER325
HSER396
BSER-13
BSER-12
BSER-10
BSER60
CSER-8
CSER-7
CSER-5
CSER66
HSER322
HSER323

site_idSWS_FT_FI7
Number of Residues2
DetailsMOD_RES: Phosphothreonine => ECO:0000250|UniProtKB:P11798
ChainResidueDetails
BTHR-7
BTHR-6
CTHR-2
CTHR-1
DTHR-4
DTHR-3
ETHR-6
ETHR-5
FTHR-7
FTHR-6
GTHR8
GTHR9
ITHR-7
ITHR-6
JTHR-2
JTHR-1
KTHR-4
KTHR-3
LTHR-6
LTHR-5
MTHR-7
MTHR-6
HTHR328
HTHR329

219869

PDB entries from 2024-05-15

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