6TB4

Structure of SAGA bound to TBP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000124	cellular_component	SAGA complex
A	0003712	molecular_function	transcription coregulator activity
A	0003713	molecular_function	transcription coactivator activity
A	0005634	cellular_component	nucleus
A	0006325	biological_process	chromatin organization
A	0006357	biological_process	regulation of transcription by RNA polymerase II
A	0006366	biological_process	transcription by RNA polymerase II
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0046695	cellular_component	SLIK (SAGA-like) complex
A	0070461	cellular_component	SAGA-type complex
C	0000124	cellular_component	SAGA complex
C	0006357	biological_process	regulation of transcription by RNA polymerase II
C	0031048	biological_process	regulatory ncRNA-mediated heterochromatin formation
C	1904802	biological_process	RITS complex assembly
D	0000124	cellular_component	SAGA complex
D	0003712	molecular_function	transcription coregulator activity
D	0006366	biological_process	transcription by RNA polymerase II
D	0043229	cellular_component	intracellular organelle
D	0046982	molecular_function	protein heterodimerization activity
E	0000124	cellular_component	SAGA complex
E	0005198	molecular_function	structural molecule activity
E	0006357	biological_process	regulation of transcription by RNA polymerase II
E	0046695	cellular_component	SLIK (SAGA-like) complex
E	0046982	molecular_function	protein heterodimerization activity
F	0000124	cellular_component	SAGA complex
F	0003712	molecular_function	transcription coregulator activity
F	0006357	biological_process	regulation of transcription by RNA polymerase II
G	0005634	cellular_component	nucleus
G	0005669	cellular_component	transcription factor TFIID complex
G	0006367	biological_process	transcription initiation at RNA polymerase II promoter
G	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
G	0031326	biological_process	regulation of cellular biosynthetic process
G	0080090	biological_process	regulation of primary metabolic process
H	0000124	cellular_component	SAGA complex
H	0003682	molecular_function	chromatin binding
H	0003713	molecular_function	transcription coactivator activity
H	0005634	cellular_component	nucleus
H	0005669	cellular_component	transcription factor TFIID complex
H	0005829	cellular_component	cytosol
H	0006325	biological_process	chromatin organization
H	0006357	biological_process	regulation of transcription by RNA polymerase II
H	0006366	biological_process	transcription by RNA polymerase II
H	0006367	biological_process	transcription initiation at RNA polymerase II promoter
H	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
H	0042802	molecular_function	identical protein binding
H	0045944	biological_process	positive regulation of transcription by RNA polymerase II
H	0046695	cellular_component	SLIK (SAGA-like) complex
H	0046982	molecular_function	protein heterodimerization activity
H	0051123	biological_process	RNA polymerase II preinitiation complex assembly
H	0060090	molecular_function	molecular adaptor activity
H	0061629	molecular_function	RNA polymerase II-specific DNA-binding transcription factor binding
H	2000144	biological_process	positive regulation of DNA-templated transcription initiation
I	0000124	cellular_component	SAGA complex
I	0003682	molecular_function	chromatin binding
I	0003713	molecular_function	transcription coactivator activity
I	0005634	cellular_component	nucleus
I	0005669	cellular_component	transcription factor TFIID complex
I	0006325	biological_process	chromatin organization
I	0006352	biological_process	DNA-templated transcription initiation
I	0006357	biological_process	regulation of transcription by RNA polymerase II
I	0006366	biological_process	transcription by RNA polymerase II
I	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
I	0042802	molecular_function	identical protein binding
I	0045944	biological_process	positive regulation of transcription by RNA polymerase II
I	0046695	cellular_component	SLIK (SAGA-like) complex
I	0046982	molecular_function	protein heterodimerization activity
I	0051123	biological_process	RNA polymerase II preinitiation complex assembly
I	0060090	molecular_function	molecular adaptor activity
J	0000124	cellular_component	SAGA complex
J	0003682	molecular_function	chromatin binding
J	0005634	cellular_component	nucleus
J	0005669	cellular_component	transcription factor TFIID complex
J	0006325	biological_process	chromatin organization
J	0006352	biological_process	DNA-templated transcription initiation
J	0006357	biological_process	regulation of transcription by RNA polymerase II
J	0006366	biological_process	transcription by RNA polymerase II
J	0006367	biological_process	transcription initiation at RNA polymerase II promoter
J	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity
J	0042802	molecular_function	identical protein binding
J	0043229	cellular_component	intracellular organelle
J	0045944	biological_process	positive regulation of transcription by RNA polymerase II
J	0046695	cellular_component	SLIK (SAGA-like) complex
J	0051123	biological_process	RNA polymerase II preinitiation complex assembly
J	0060090	molecular_function	molecular adaptor activity
J	1990841	molecular_function	promoter-specific chromatin binding
K	0000124	cellular_component	SAGA complex
K	0003677	molecular_function	DNA binding
K	0005634	cellular_component	nucleus
K	0005669	cellular_component	transcription factor TFIID complex
K	0006352	biological_process	DNA-templated transcription initiation
K	0017025	molecular_function	TBP-class protein binding
K	0046982	molecular_function	protein heterodimerization activity
K	0051123	biological_process	RNA polymerase II preinitiation complex assembly
L	0000124	cellular_component	SAGA complex
L	0005634	cellular_component	nucleus
L	0006281	biological_process	DNA repair
L	0006355	biological_process	regulation of DNA-templated transcription
L	0035267	cellular_component	NuA4 histone acetyltransferase complex
M	0000120	cellular_component	RNA polymerase I transcription regulator complex
M	0000979	molecular_function	RNA polymerase II core promoter sequence-specific DNA binding
M	0001006	molecular_function	RNA polymerase III type 3 promoter sequence-specific DNA binding
M	0003677	molecular_function	DNA binding
M	0005634	cellular_component	nucleus
M	0005669	cellular_component	transcription factor TFIID complex
M	0006352	biological_process	DNA-templated transcription initiation
M	0006361	biological_process	transcription initiation at RNA polymerase I promoter
M	0006367	biological_process	transcription initiation at RNA polymerase II promoter
M	0016251	molecular_function	RNA polymerase II general transcription initiation factor activity

Functional Information from PROSITE/UniProt

site_id	PS00351
Number of Residues	50
Details	TFIID Transcription factor TFIID repeat signature. YnPkrFaaVImRirePKttaLIFaSGKMvvtGAKseddsklAsrkyariI

Chain	Residue	Details
M	TYR94-ILE143
M	TYR185-LEU234

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site_id	PS00018
Number of Residues	13
Details	EF_HAND_1 EF-hand calcium-binding domain. DSDSSNILTseDY

Chain	Residue	Details
L	ASP2069-TYR2081

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site_id	PS00633
Number of Residues	58
Details	BROMODOMAIN_1 Bromodomain signature. StaFlnrvSkreap..NYYqiIkkpMdlntVmkklksfq..Ykskqefvddlml.IwkNCltY

Chain	Residue	Details
E	SER464-TYR521

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site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. LFTGssDkTARMWDI

Chain	Residue	Details
G	LEU552-ILE566
G	LEU594-ILE608
G	LEU637-VAL651

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