6SB1
Crystal structure of murine perforin-2 P2 domain crystal form 1
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 701 |
| Chain | Residue |
| A | GLU384 |
| A | CYS385 |
| A | THR386 |
| A | GLU398 |
| A | PHE407 |
| A | ARG458 |
| A | HOH812 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 702 |
| Chain | Residue |
| A | HOH813 |
| A | HOH829 |
| A | GLN399 |
| A | LEU402 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 701 |
| Chain | Residue |
| B | GLU384 |
| B | CYS385 |
| B | THR386 |
| B | GLU398 |
| B | ARG458 |
| B | HOH824 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 6 |
| Details | SITE: Cleavage; by LGMN => ECO:0000269|PubMed:37347855 |
| Chain | Residue | Details |
| A | ASN359 | |
| B | ASN352 | |
| B | ASN357 | |
| B | ASN359 | |
| A | ASN352 | |
| A | ASN357 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by trypsin => ECO:0000305|PubMed:26402460, ECO:0000305|PubMed:37347855 |
| Chain | Residue | Details |
| A | LYS628 | |
| B | LYS628 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN375 | |
| B | ASN375 |
