6O84
Cryo-EM structure of OTOP3 from xenopus tropicalis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0015252 | molecular_function | proton channel activity |
| A | 0016020 | cellular_component | membrane |
| A | 0034220 | biological_process | monoatomic ion transmembrane transport |
| A | 0042802 | molecular_function | identical protein binding |
| A | 1902600 | biological_process | proton transmembrane transport |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006811 | biological_process | monoatomic ion transport |
| B | 0015252 | molecular_function | proton channel activity |
| B | 0016020 | cellular_component | membrane |
| B | 0034220 | biological_process | monoatomic ion transmembrane transport |
| B | 0042802 | molecular_function | identical protein binding |
| B | 1902600 | biological_process | proton transmembrane transport |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 234 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:30973323 |
| Chain | Residue | Details |
| A | MET1-ARG112 | |
| A | LEU675-ALA681 | |
| B | MET1-ARG112 | |
| B | LEU675-ALA681 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 40 |
| Details | TRANSMEM: Helical; Name=1 => ECO:0000269|PubMed:30973323, ECO:0007744|PDB:6O84 |
| Chain | Residue | Details |
| A | LEU113-VAL133 | |
| B | LEU113-VAL133 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 212 |
| Details | TOPO_DOM: Extracellular => ECO:0000305 |
| Chain | Residue | Details |
| A | ALA134-ARG143 | |
| B | UNK379-UNK392 | |
| B | ALA530-LEU540 | |
| B | GLY633-ILE651 | |
| A | GLY205-LEU216 | |
| A | ASP272-PRO317 | |
| A | UNK379-UNK392 | |
| A | ALA530-LEU540 | |
| A | GLY633-ILE651 | |
| B | ALA134-ARG143 | |
| B | GLY205-LEU216 | |
| B | ASP272-PRO317 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 44 |
| Details | TRANSMEM: Helical; Name=2 => ECO:0000269|PubMed:30973323, ECO:0007744|PDB:6O84 |
| Chain | Residue | Details |
| A | ASP144-PHE166 | |
| B | ASP144-PHE166 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 372 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000305 |
| Chain | Residue | Details |
| A | ILE167-ALA182 | |
| B | GLU564-GLU614 | |
| A | LYS241-HIS248 | |
| A | LYS335-UNK358 | |
| A | UNK416-LYS507 | |
| A | GLU564-GLU614 | |
| B | ILE167-ALA182 | |
| B | LYS241-HIS248 | |
| B | LYS335-UNK358 | |
| B | UNK416-LYS507 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 42 |
| Details | TRANSMEM: Helical; Name=3 => ECO:0000269|PubMed:30973323, ECO:0007744|PDB:6O84 |
| Chain | Residue | Details |
| A | MET183-ILE204 | |
| B | MET183-ILE204 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 46 |
| Details | TRANSMEM: Helical; Name=4 => ECO:0000269|PubMed:30973323, ECO:0007744|PDB:6O84 |
| Chain | Residue | Details |
| A | MET217-CYS240 | |
| B | MET217-CYS240 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 44 |
| Details | TRANSMEM: Helical; Name=5 => ECO:0000269|PubMed:30973323, ECO:0007744|PDB:6O84 |
| Chain | Residue | Details |
| A | SER249-ILE271 | |
| B | SER249-ILE271 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 32 |
| Details | TRANSMEM: Helical; Name=6 => ECO:0000269|PubMed:30973323, ECO:0007744|PDB:6O84 |
| Chain | Residue | Details |
| A | PHE318-TRP334 | |
| B | PHE318-TRP334 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 38 |
| Details | TRANSMEM: Helical; Name=7 => ECO:0000269|PubMed:30973323, ECO:0007744|PDB:6O84 |
| Chain | Residue | Details |
| A | UNK359-UNK378 | |
| B | UNK359-UNK378 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 44 |
| Details | TRANSMEM: Helical; Name=8 => ECO:0000269|PubMed:30973323, ECO:0007744|PDB:6O84 |
| Chain | Residue | Details |
| A | UNK393-UNK415 | |
| B | UNK393-UNK415 |
| site_id | SWS_FT_FI12 |
| Number of Residues | 42 |
| Details | TRANSMEM: Helical; Name=9 => ECO:0000269|PubMed:30973323, ECO:0007744|PDB:6O84 |
| Chain | Residue | Details |
| A | LEU508-ILE529 | |
| B | LEU508-ILE529 |
| site_id | SWS_FT_FI13 |
| Number of Residues | 44 |
| Details | TRANSMEM: Helical; Name=10 => ECO:0000269|PubMed:30973323, ECO:0007744|PDB:6O84 |
| Chain | Residue | Details |
| A | SER541-ILE563 | |
| B | SER541-ILE563 |
| site_id | SWS_FT_FI14 |
| Number of Residues | 34 |
| Details | TRANSMEM: Helical; Name=11 => ECO:0000269|PubMed:30973323, ECO:0007744|PDB:6O84 |
| Chain | Residue | Details |
| A | MET615-PHE632 | |
| B | MET615-PHE632 |
| site_id | SWS_FT_FI15 |
| Number of Residues | 44 |
| Details | TRANSMEM: Helical; Name=12 => ECO:0000269|PubMed:30973323, ECO:0007744|PDB:6O84 |
| Chain | Residue | Details |
| A | TRP652-LEU674 | |
| B | TRP652-LEU674 |
