6M8A

Crystal structure of the core catalytic domain of human inositol phosphate multikinase in complex with luteolin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016301	molecular_function	kinase activity
A	0032958	biological_process	inositol phosphate biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue LU2 A 501

Chain	Residue
A	ILE65
A	ASP385
A	GLN67
A	LYS75
A	PRO111
A	GLU131
A	ASP132
A	VAL133
A	ILE142
A	ILE384

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	BINDING: BINDING => ECO:0000269|PubMed:28882892, ECO:0007744|PDB:5W2H, ECO:0007744|PDB:5W2I

Chain	Residue	Details
A	ARG82
A	GLU131
A	ASP144
A	LYS146
A	GLN196
A	ASP385
A	HIS388
A	LYS75

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site_id	SWS_FT_FI2
Number of Residues	1
Details	BINDING: BINDING => ECO:0000269|PubMed:28882892, ECO:0007744|PDB:5W2H

Chain	Residue	Details
A	LYS160

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