5ZHP
M3 muscarinic acetylcholine receptor in complex with a selective antagonist
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003796 | molecular_function | lysozyme activity |
| A | 0004930 | molecular_function | G protein-coupled receptor activity |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| A | 0009253 | biological_process | peptidoglycan catabolic process |
| A | 0016020 | cellular_component | membrane |
| A | 0016907 | molecular_function | G protein-coupled acetylcholine receptor activity |
| A | 0016998 | biological_process | cell wall macromolecule catabolic process |
| B | 0003796 | molecular_function | lysozyme activity |
| B | 0004930 | molecular_function | G protein-coupled receptor activity |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0007186 | biological_process | G protein-coupled receptor signaling pathway |
| B | 0009253 | biological_process | peptidoglycan catabolic process |
| B | 0016020 | cellular_component | membrane |
| B | 0016907 | molecular_function | G protein-coupled acetylcholine receptor activity |
| B | 0016998 | biological_process | cell wall macromolecule catabolic process |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 46 |
| Details | TRANSMEM: Helical; Name=1 |
| Chain | Residue | Details |
| A | VAL67-VAL90 | |
| B | VAL67-VAL90 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 62 |
| Details | TOPO_DOM: Cytoplasmic => ECO:0000269|PubMed:22358844 |
| Chain | Residue | Details |
| A | ALA91-ASN103 | |
| A | ASP164-ARG183 | |
| B | ASP164-ARG183 | |
| B | ALA91-ASN103 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 50 |
| Details | TRANSMEM: Helical; Name=2 |
| Chain | Residue | Details |
| A | TYR104-ILE129 | |
| B | TYR104-ILE129 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 88 |
| Details | TOPO_DOM: Extracellular => ECO:0000269|PubMed:22358844 |
| Chain | Residue | Details |
| A | MET130-ASP141 | |
| A | TRP206-PRO228 | |
| A | THR514-TRP525 | |
| B | MET130-ASP141 | |
| B | TRP206-PRO228 | |
| B | THR514-TRP525 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 42 |
| Details | TRANSMEM: Helical; Name=3 |
| Chain | Residue | Details |
| A | LEU142-PHE163 | |
| B | LEU142-PHE163 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 42 |
| Details | TRANSMEM: Helical; Name=4 |
| Chain | Residue | Details |
| A | ALA184-PHE205 | |
| B | ALA184-PHE205 |
| site_id | SWS_FT_FI7 |
| Number of Residues | 44 |
| Details | TRANSMEM: Helical; Name=5 |
| Chain | Residue | Details |
| A | THR229-TRP251 | |
| B | THR229-TRP251 |
| site_id | SWS_FT_FI8 |
| Number of Residues | 44 |
| Details | TRANSMEM: Helical; Name=6 |
| Chain | Residue | Details |
| A | THR491-ASN513 | |
| B | THR491-ASN513 |
| site_id | SWS_FT_FI9 |
| Number of Residues | 38 |
| Details | TRANSMEM: Helical; Name=7 |
| Chain | Residue | Details |
| A | ASN526-LEU545 | |
| B | ASN526-LEU545 |
| site_id | SWS_FT_FI10 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:8266098 |
| Chain | Residue | Details |
| A | PHE1061 | |
| B | PHE1061 |
| site_id | SWS_FT_FI11 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000303|PubMed:7831309 |
| Chain | Residue | Details |
| A | SER1074 | |
| A | ASN1089 | |
| B | SER1074 | |
| B | ASN1089 |
