5YXY

Crystal structure of the HyhL-HypA complex (form I)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008901	molecular_function	ferredoxin hydrogenase activity
A	0016151	molecular_function	nickel cation binding
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
B	0008901	molecular_function	ferredoxin hydrogenase activity
B	0016151	molecular_function	nickel cation binding
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
C	0008901	molecular_function	ferredoxin hydrogenase activity
C	0016151	molecular_function	nickel cation binding
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
D	0008270	molecular_function	zinc ion binding
D	0016151	molecular_function	nickel cation binding
D	0036211	biological_process	protein modification process
D	0046872	molecular_function	metal ion binding
D	0051604	biological_process	protein maturation
E	0008270	molecular_function	zinc ion binding
E	0016151	molecular_function	nickel cation binding
E	0036211	biological_process	protein modification process
E	0046872	molecular_function	metal ion binding
E	0051604	biological_process	protein maturation
F	0008270	molecular_function	zinc ion binding
F	0016151	molecular_function	nickel cation binding
F	0036211	biological_process	protein modification process
F	0046872	molecular_function	metal ion binding
F	0051604	biological_process	protein maturation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN D 701

Chain	Residue
D	CYS73
D	CYS76
D	CYS110
D	CYS113

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site_id	AC2
Number of Residues	4
Details	binding site for residue ZN E 701

Chain	Residue
E	CYS73
E	CYS76
E	CYS110
E	CYS113

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site_id	AC3
Number of Residues	4
Details	binding site for residue ZN F 701

Chain	Residue
F	CYS76
F	CYS110
F	CYS113
F	CYS73

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Functional Information from PROSITE/UniProt

site_id	PS01249
Number of Residues	43
Details	HYPA Hydrogenases expression/synthesis hypA family signature. GelqdVaediVkfAMeqlfagTiaeg.AeIeFveeeavfkCrnC

Chain	Residue	Details
D	GLY34-CYS76

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site_id	PS00508
Number of Residues	10
Details	NI_HGENASE_L_2 Nickel-dependent hydrogenases large subunit signature 2. YDPCISCsv.H

Chain	Residue	Details
A	TYR415-HIS424

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	BINDING: BINDING => ECO:0000269|PubMed:26056269, ECO:0007744|PDB:5AUN, ECO:0007744|PDB:5AUO

Chain	Residue	Details
E	MET1
E	HIS2
E	HIS98
F	MET1
F	HIS2
F	HIS98
D	MET1
D	HIS2
D	HIS98

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00213, ECO:0000269|PubMed:19769985, ECO:0000269|PubMed:26056269, ECO:0007744|PDB:3A43, ECO:0007744|PDB:3A44, ECO:0007744|PDB:5AUN, ECO:0007744|PDB:5AUO, ECO:0007744|PDB:5AUP

Chain	Residue	Details
D	CYS113
E	CYS73
E	CYS76
E	CYS110
E	CYS113
F	CYS73
F	CYS76
F	CYS110
F	CYS113
D	CYS73
D	CYS76
D	CYS110

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