5MHF

Murine endoplasmic reticulum alpha-glucosidase I with N-9'-methoxynonyl-1-deoxynojirimycin.

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004573	molecular_function	Glc3Man9GlcNAc2 oligosaccharide glucosidase activity
A	0005783	cellular_component	endoplasmic reticulum
A	0005789	cellular_component	endoplasmic reticulum membrane
A	0005975	biological_process	carbohydrate metabolic process
A	0006487	biological_process	protein N-linked glycosylation
A	0009311	biological_process	oligosaccharide metabolic process
A	0016020	cellular_component	membrane
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0004573	molecular_function	Glc3Man9GlcNAc2 oligosaccharide glucosidase activity
B	0005783	cellular_component	endoplasmic reticulum
B	0005789	cellular_component	endoplasmic reticulum membrane
B	0005975	biological_process	carbohydrate metabolic process
B	0006487	biological_process	protein N-linked glycosylation
B	0009311	biological_process	oligosaccharide metabolic process
B	0016020	cellular_component	membrane
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0004573	molecular_function	Glc3Man9GlcNAc2 oligosaccharide glucosidase activity
C	0005783	cellular_component	endoplasmic reticulum
C	0005789	cellular_component	endoplasmic reticulum membrane
C	0005975	biological_process	carbohydrate metabolic process
C	0006487	biological_process	protein N-linked glycosylation
C	0009311	biological_process	oligosaccharide metabolic process
C	0016020	cellular_component	membrane
C	0016787	molecular_function	hydrolase activity
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0004573	molecular_function	Glc3Man9GlcNAc2 oligosaccharide glucosidase activity
D	0005783	cellular_component	endoplasmic reticulum
D	0005789	cellular_component	endoplasmic reticulum membrane
D	0005975	biological_process	carbohydrate metabolic process
D	0006487	biological_process	protein N-linked glycosylation
D	0009311	biological_process	oligosaccharide metabolic process
D	0016020	cellular_component	membrane
D	0016787	molecular_function	hydrolase activity
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3076
Details	TOPO_DOM: Lumenal => ECO:0000255

Chain	Residue	Details
A	ARG65-TYR834
B	ARG65-TYR834
C	ARG65-TYR834
D	ARG65-TYR834

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site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000305|PubMed:32227946

Chain	Residue	Details
A	ASP580
B	ASP580
C	ASP580
D	ASP580

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site_id	SWS_FT_FI3
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000305|PubMed:32227946

Chain	Residue	Details
A	GLU804
B	GLU804
C	GLU804
D	GLU804

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site_id	SWS_FT_FI4
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000250|UniProtKB:Q13724

Chain	Residue	Details
A	ASN654
B	ASN654
C	ASN654
D	ASN654

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