5B74

Crystal structure of conjoined Pyrococcus furiosus L-asparaginase with peptide

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	binding site for residue FLC A 201

Chain	Residue
A	GLY10
B	HOH502
A	THR11
A	ASP51
A	SER52
A	THR53
A	GLY82
A	THR83
A	ASP84
A	SER109

---

site_id	AC2
Number of Residues	3
Details	binding site for residue CL A 202

Chain	Residue
A	VAL71
A	TYR74
A	ILE102

---

site_id	AC3
Number of Residues	1
Details	binding site for residue CL B 401

Chain	Residue
B	ASP214

---

Functional Information from PROSITE/UniProt

site_id	PS00917
Number of Residues	11
Details	ASN_GLN_ASE_2 Asparaginase / glutaminase active site signature 2. GiIvtHGTDTL

Chain	Residue	Details
A	GLY76-LEU86

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Charge relay system => ECO:0000305|PubMed:25478837

Chain	Residue	Details
B	TYR273

---

site_id	SWS_FT_FI2
Number of Residues	3
Details	ACT_SITE: Charge relay system => ECO:0000305|PubMed:25478837

Chain	Residue	Details
A	THR83
A	ASP84
A	LYS154

---

site_id	SWS_FT_FI3
Number of Residues	5
Details	BINDING: BINDING => ECO:0000269|PubMed:25478837, ECO:0007744|PDB:4NJE, ECO:0007744|PDB:5B5U

Chain	Residue	Details
A	ASP51
A	SER52
A	THR83
A	ASP84
A	THR11

---