5B1H
Crystal structure of cystathionine beta-synthase from Lactobacillus plantarum
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004122 | molecular_function | cystathionine beta-synthase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006535 | biological_process | cysteine biosynthetic process from serine |
A | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
A | 0016829 | molecular_function | lyase activity |
A | 0019344 | biological_process | cysteine biosynthetic process |
B | 0004122 | molecular_function | cystathionine beta-synthase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0006535 | biological_process | cysteine biosynthetic process from serine |
B | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
B | 0016829 | molecular_function | lyase activity |
B | 0019344 | biological_process | cysteine biosynthetic process |
C | 0004122 | molecular_function | cystathionine beta-synthase activity |
C | 0005737 | cellular_component | cytoplasm |
C | 0006535 | biological_process | cysteine biosynthetic process from serine |
C | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
C | 0016829 | molecular_function | lyase activity |
C | 0019344 | biological_process | cysteine biosynthetic process |
D | 0004122 | molecular_function | cystathionine beta-synthase activity |
D | 0005737 | cellular_component | cytoplasm |
D | 0006535 | biological_process | cysteine biosynthetic process from serine |
D | 0016765 | molecular_function | transferase activity, transferring alkyl or aryl (other than methyl) groups |
D | 0016829 | molecular_function | lyase activity |
D | 0019344 | biological_process | cysteine biosynthetic process |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 3 |
Details | binding site for residue SO4 A 401 |
Chain | Residue |
A | ARG250 |
A | HIS251 |
A | ARG254 |
site_id | AC2 |
Number of Residues | 6 |
Details | binding site for residue SO4 A 402 |
Chain | Residue |
A | SER135 |
A | ASN136 |
A | SO4403 |
A | HOH529 |
D | LYS62 |
D | ASN136 |
site_id | AC3 |
Number of Residues | 7 |
Details | binding site for residue SO4 A 403 |
Chain | Residue |
A | LYS62 |
A | ASN136 |
A | SO4402 |
A | HOH525 |
A | HOH530 |
D | SER135 |
D | ASN136 |
site_id | AC4 |
Number of Residues | 8 |
Details | binding site for residue SO4 A 404 |
Chain | Residue |
A | THR69 |
A | ALA70 |
A | GLY71 |
A | ASN72 |
A | THR73 |
A | GLN142 |
A | HOH544 |
A | HOH548 |
site_id | AC5 |
Number of Residues | 2 |
Details | binding site for residue GOL A 405 |
Chain | Residue |
A | MET1 |
C | MET1 |
site_id | AC6 |
Number of Residues | 10 |
Details | binding site for residue GOL A 406 |
Chain | Residue |
A | HIS5 |
A | GLN7 |
A | GLN82 |
A | ALA83 |
B | HIS25 |
B | ASN281 |
C | PRO19 |
C | ASP255 |
C | HIS256 |
C | HOH505 |
site_id | AC7 |
Number of Residues | 5 |
Details | binding site for residue GOL A 407 |
Chain | Residue |
A | LEU54 |
A | HIS84 |
A | HOH531 |
B | ASN24 |
B | THR276 |
site_id | AC8 |
Number of Residues | 4 |
Details | binding site for residue GOL A 408 |
Chain | Residue |
A | THR169 |
A | ALA280 |
A | ASN281 |
A | SER282 |
site_id | AC9 |
Number of Residues | 3 |
Details | binding site for residue SO4 B 401 |
Chain | Residue |
B | ARG250 |
B | HIS251 |
B | ARG254 |
site_id | AD1 |
Number of Residues | 7 |
Details | binding site for residue SO4 B 402 |
Chain | Residue |
B | THR69 |
B | ALA70 |
B | GLY71 |
B | ASN72 |
B | THR73 |
B | GLN142 |
B | HOH554 |
site_id | AD2 |
Number of Residues | 6 |
Details | binding site for residue GOL B 403 |
Chain | Residue |
A | HIS85 |
B | ILE20 |
B | GLU21 |
B | VAL22 |
B | HIS25 |
B | HOH514 |
site_id | AD3 |
Number of Residues | 2 |
Details | binding site for residue GOL B 404 |
Chain | Residue |
B | ARG56 |
B | ARG58 |
site_id | AD4 |
Number of Residues | 4 |
Details | binding site for residue GOL B 405 |
Chain | Residue |
B | HIS85 |
B | ARG254 |
B | HOH561 |
C | ALA132 |
site_id | AD5 |
Number of Residues | 4 |
Details | binding site for residue GOL B 406 |
Chain | Residue |
B | THR169 |
B | PRO279 |
B | ALA280 |
B | SER282 |
site_id | AD6 |
Number of Residues | 3 |
Details | binding site for residue SO4 C 401 |
Chain | Residue |
C | ARG250 |
C | HIS251 |
C | ARG254 |
site_id | AD7 |
Number of Residues | 8 |
Details | binding site for residue SO4 C 402 |
Chain | Residue |
C | THR69 |
C | ALA70 |
C | GLY71 |
C | ASN72 |
C | THR73 |
C | GLN142 |
C | HOH535 |
C | HOH541 |
site_id | AD8 |
Number of Residues | 7 |
Details | binding site for residue SO4 C 403 |
Chain | Residue |
B | SER135 |
B | ASN136 |
C | LYS62 |
C | ASN136 |
C | SO4404 |
C | HOH526 |
C | HOH539 |
site_id | AD9 |
Number of Residues | 6 |
Details | binding site for residue SO4 C 404 |
Chain | Residue |
B | LYS62 |
B | ASN136 |
C | SER135 |
C | ASN136 |
C | SO4403 |
C | HOH536 |
site_id | AE1 |
Number of Residues | 4 |
Details | binding site for residue GOL C 405 |
Chain | Residue |
C | HIS154 |
C | THR155 |
C | GLU159 |
C | HOH530 |
site_id | AE2 |
Number of Residues | 6 |
Details | binding site for residue GOL C 406 |
Chain | Residue |
C | LEU54 |
C | ALA61 |
C | HIS84 |
C | HOH556 |
D | ASN24 |
D | THR276 |
site_id | AE3 |
Number of Residues | 4 |
Details | binding site for residue GOL C 407 |
Chain | Residue |
C | THR169 |
C | ALA280 |
C | ASN281 |
C | SER282 |
site_id | AE4 |
Number of Residues | 7 |
Details | binding site for residue SO4 D 401 |
Chain | Residue |
D | THR69 |
D | ALA70 |
D | GLY71 |
D | ASN72 |
D | THR73 |
D | GLN142 |
D | HOH514 |
site_id | AE5 |
Number of Residues | 3 |
Details | binding site for residue SO4 D 402 |
Chain | Residue |
D | ARG250 |
D | HIS251 |
D | ARG254 |
site_id | AE6 |
Number of Residues | 6 |
Details | binding site for residue GOL D 403 |
Chain | Residue |
C | HIS85 |
D | ILE20 |
D | GLU21 |
D | VAL22 |
D | HIS25 |
D | HOH512 |
site_id | AE7 |
Number of Residues | 5 |
Details | binding site for residue GOL D 404 |
Chain | Residue |
A | PRO165 |
A | HIS283 |
D | LEU2 |
D | GLN4 |
D | GLU8 |
site_id | AE8 |
Number of Residues | 6 |
Details | binding site for residue GOL D 405 |
Chain | Residue |
D | THR169 |
D | PRO279 |
D | ALA280 |
D | SER282 |
D | HOH518 |
D | HOH548 |
Functional Information from PROSITE/UniProt
site_id | PS00901 |
Number of Residues | 19 |
Details | CYS_SYNTHASE Cysteine synthase/cystathionine beta-synthase P-phosphate attachment site. KlEmfn.PGgSIKdRlGayL |
Chain | Residue | Details |
A | LYS31-LEU49 |