Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| A | 0006508 | biological_process | proteolysis |
| B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 101 |
| Chain | Residue |
| B | ASP135 |
| B | GLY178 |
| B | PRO179 |
| site_id | AC2 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE 478 B 401 |
| Chain | Residue |
| A | GLY49 |
| A | ILE50 |
| A | VAL82 |
| B | ASP125 |
| B | GLY127 |
| B | ALA128 |
| B | ASN130 |
| B | ILE132 |
| B | GLY148 |
| B | GLY149 |
| B | ILE150 |
| B | PRO181 |
| B | VAL182 |
| B | HOH501 |
| A | ASP25 |
| A | GLY27 |
| A | ALA28 |
| A | ASP29 |
| A | ASN30 |
| A | GLY48 |
| site_id | AC3 |
| Number of Residues | 17 |
| Details | BINDING SITE FOR RESIDUE 478 B 402 |
| Chain | Residue |
| A | TRP6 |
| A | GLY40 |
| A | ARG41 |
| B | TRP142 |
| B | PRO144 |
| B | LYS145 |
| B | LYS155 |
| B | VAL156 |
| B | ARG157 |
| B | VAL177 |
| B | PRO179 |
| B | GLN192 |
| B | ILE193 |
| B | GLY194 |
| B | CL404 |
| B | HOH508 |
| B | HOH545 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 403 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 404 |
Functional Information from PROSITE/UniProt
| site_id | PS00141 |
| Number of Residues | 12 |
| Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADNTIF |
| Chain | Residue | Details |
| A | ALA22-PHE33 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP25 | |
| B | ASP125 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Cleavage; by viral protease => ECO:0000250 |
| Chain | Residue | Details |
| A | PHE99 | |
| B | PHE199 | |
