4H8R

Imipenem complex of GES-5 carbapenemase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008800	molecular_function	beta-lactamase activity
A	0017001	biological_process	antibiotic catabolic process
A	0030655	biological_process	beta-lactam antibiotic catabolic process
A	0046677	biological_process	response to antibiotic
B	0008800	molecular_function	beta-lactamase activity
B	0017001	biological_process	antibiotic catabolic process
B	0030655	biological_process	beta-lactam antibiotic catabolic process
B	0046677	biological_process	response to antibiotic

Functional Information from PDB Data

site_id	AC1
Number of Residues	14
Details	BINDING SITE FOR RESIDUE IM2 A 501

Chain	Residue
A	CYS63
A	THR232
A	ARG238
A	HOH601
A	HOH625
A	HOH786
A	SER64
A	SER125
A	ASN127
A	GLU161
A	SER165
A	LYS229
A	THR230
A	GLY231

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site_id	AC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 502

Chain	Residue
A	ARG204

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site_id	AC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 504

Chain	Residue
A	MET56

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD A 505

Chain	Residue
A	ARG105
B	GLN210

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site_id	AC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 506

Chain	Residue
A	LYS222

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site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD A 507

Chain	Residue
A	NA509

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site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA A 509

Chain	Residue
A	PRO93
A	ASP94
A	IOD507

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site_id	AC8
Number of Residues	13
Details	BINDING SITE FOR RESIDUE IM2 B 501

Chain	Residue
B	CYS63
B	SER64
B	SER125
B	ASN127
B	GLU161
B	SER165
B	LYS229
B	THR230
B	GLY231
B	THR232
B	ARG238
B	HOH601
B	HOH640

---

site_id	AC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 503

Chain	Residue
B	ARG204

---

site_id	BC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 504

Chain	Residue
A	GLN210
B	ARG105

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site_id	BC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD B 505

Chain	Residue
B	LYS149
B	GLN280
B	HOH753

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site_id	BC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE IOD B 506

Chain	Residue
B	GLY92
B	ASP94
B	ARG135

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site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 507

Chain	Residue
B	LYS187

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site_id	BC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE IOD B 508

Chain	Residue
B	THR177

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site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE IOD B 509

Chain	Residue
B	ALA57
B	GLN58

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site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE NA B 510

Chain	Residue
B	LYS160
B	GLU163

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site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE NA B 513

Chain	Residue
B	THR113

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