4GUD
Crystal Structure of Amidotransferase HisH from Vibrio cholerae
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000105 | biological_process | histidine biosynthetic process |
| A | 0000107 | molecular_function | imidazoleglycerol-phosphate synthase activity |
| A | 0004359 | molecular_function | glutaminase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006541 | biological_process | glutamine metabolic process |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0016763 | molecular_function | pentosyltransferase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016829 | molecular_function | lyase activity |
| B | 0000105 | biological_process | histidine biosynthetic process |
| B | 0000107 | molecular_function | imidazoleglycerol-phosphate synthase activity |
| B | 0004359 | molecular_function | glutaminase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006541 | biological_process | glutamine metabolic process |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0016763 | molecular_function | pentosyltransferase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0016829 | molecular_function | lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE GOL A 301 |
| Chain | Residue |
| A | TRP125 |
| A | ARG188 |
| A | HOH426 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG A 302 |
| Chain | Residue |
| A | TRP125 |
| B | SER151 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE 1PE B 301 |
| Chain | Residue |
| B | EDO302 |
| A | SER151 |
| B | TRP125 |
| B | TYR147 |
| B | ARG188 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE EDO B 302 |
| Chain | Residue |
| B | 1PE301 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Nucleophile => ECO:0000250 |
| Chain | Residue | Details |
| A | CYS79 | |
| B | CYS79 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: ACT_SITE => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS185 | |
| A | GLU187 | |
| B | HIS185 | |
| B | GLU187 |
