3U3Z
Structure of human microcephalin (MCPH1) tandem BRCT domains in complex with an H2A.X peptide phosphorylated at Ser139 and Tyr142
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 9 |
Details | BINDING SITE FOR RESIDUE GOL A 1 |
Chain | Residue |
A | HOH78 |
A | HOH200 |
A | PRO727 |
A | SER765 |
A | ALA767 |
A | PRO799 |
A | TYR800 |
A | SER801 |
A | GLY802 |
site_id | AC2 |
Number of Residues | 3 |
Details | BINDING SITE FOR RESIDUE GOL A 2 |
Chain | Residue |
A | LEU714 |
A | TRP715 |
A | GLU718 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine; by ATM, ATR and PRKDC => ECO:0000269|PubMed:10477747, ECO:0000269|PubMed:10734083, ECO:0000269|PubMed:10959836, ECO:0000269|PubMed:11673449, ECO:0000269|PubMed:12419185, ECO:0000269|PubMed:12607005, ECO:0000269|PubMed:12660252, ECO:0000269|PubMed:12697768, ECO:0000269|PubMed:14627815, ECO:0000269|PubMed:15059890, ECO:0000269|PubMed:15489221, ECO:0000269|PubMed:15613478, ECO:0000269|PubMed:17709392, ECO:0000269|PubMed:22154951, ECO:0000269|PubMed:9488723, ECO:0007744|PubMed:17525332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692 |
Chain | Residue | Details |
B | SEP1 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | MOD_RES: Phosphotyrosine; by WSTF => ECO:0000269|PubMed:19092802, ECO:0000269|PubMed:19234442 |
Chain | Residue | Details |
B | PTR4 |