3R5C
Pseudomonas aeruginosa DapD (PA3666) in complex with CoA and succinate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008666 | molecular_function | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity |
| A | 0009085 | biological_process | lysine biosynthetic process |
| A | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| A | 0016746 | molecular_function | acyltransferase activity |
| A | 0019877 | biological_process | diaminopimelate biosynthetic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008666 | molecular_function | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity |
| B | 0009085 | biological_process | lysine biosynthetic process |
| B | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| B | 0016746 | molecular_function | acyltransferase activity |
| B | 0019877 | biological_process | diaminopimelate biosynthetic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000287 | molecular_function | magnesium ion binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008666 | molecular_function | 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase activity |
| C | 0009085 | biological_process | lysine biosynthetic process |
| C | 0009089 | biological_process | lysine biosynthetic process via diaminopimelate |
| C | 0016746 | molecular_function | acyltransferase activity |
| C | 0019877 | biological_process | diaminopimelate biosynthetic process |
| C | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE COA A 351 |
| Chain | Residue |
| A | THR285 |
| C | ARG317 |
| C | ARG318 |
| C | ASN319 |
| C | SER320 |
| A | GLY287 |
| A | LYS289 |
| A | LYS304 |
| A | SIN352 |
| C | GLY263 |
| C | ALA264 |
| C | GLU279 |
| C | ALA280 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SIN A 352 |
| Chain | Residue |
| A | ARG223 |
| A | SER225 |
| A | SER241 |
| A | THR242 |
| A | COA351 |
| C | GLU221 |
| C | GLY237 |
| C | GLY238 |
| C | ALA264 |
| C | HOH357 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SIN A 345 |
| Chain | Residue |
| A | GLU221 |
| A | GLY237 |
| A | GLY238 |
| A | ALA264 |
| B | ARG223 |
| B | SER225 |
| B | SER241 |
| B | THR242 |
| site_id | AC4 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE COA B 351 |
| Chain | Residue |
| A | GLY263 |
| A | ALA264 |
| A | GLU279 |
| A | ALA280 |
| A | ARG317 |
| A | ARG318 |
| A | ASN319 |
| A | SER320 |
| B | MET243 |
| B | GLY287 |
| B | LYS289 |
| B | LYS304 |
| site_id | AC5 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE COA C 351 |
| Chain | Residue |
| B | GLY263 |
| B | ALA264 |
| B | ILE277 |
| B | GLU279 |
| B | ALA280 |
| B | ARG317 |
| B | ARG318 |
| B | ASN319 |
| B | SER320 |
| B | HOH380 |
| C | GLN59 |
| C | GLN63 |
| C | MET243 |
| C | THR285 |
| C | GLY287 |
| C | LYS289 |
| C | LYS304 |
| C | SIN352 |
| site_id | AC6 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SIN C 352 |
| Chain | Residue |
| B | GLU221 |
| B | GLY238 |
| C | ARG223 |
| C | SER225 |
| C | SER241 |
| C | THR242 |
| C | COA351 |
| C | HOH375 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Acyl-anhydride intermediate => ECO:0000255|HAMAP-Rule:MF_02122 |
| Chain | Residue | Details |
| A | GLU221 | |
| B | GLU221 | |
| C | GLU221 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_02122 |
| Chain | Residue | Details |
| A | GLU205 | |
| B | GLU205 | |
| C | GLU205 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:22359568 |
| Chain | Residue | Details |
| A | ARG223 | |
| B | GLY238 | |
| B | SER241 | |
| B | ALA264 | |
| B | GLU279 | |
| B | GLY287 | |
| B | LYS304 | |
| B | ARG317 | |
| C | ARG223 | |
| C | GLY238 | |
| C | SER241 | |
| C | ALA264 | |
| C | GLU279 | |
| C | GLY287 | |
| C | LYS304 | |
| C | ARG317 | |
| A | GLY238 | |
| A | SER241 | |
| A | ALA264 | |
| A | GLU279 | |
| A | GLY287 | |
| A | LYS304 | |
| A | ARG317 | |
| B | ARG223 |
