Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3PUZ

Crystal Structure of a pre-translocation state MBP-Maltose transporter complex bound to AMP-PNP

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005886	cellular_component	plasma membrane
A	0008643	biological_process	carbohydrate transport
A	0015423	molecular_function	ABC-type maltose transporter activity
A	0015768	biological_process	maltose transport
A	0016020	cellular_component	membrane
A	0016887	molecular_function	ATP hydrolysis activity
A	0022857	molecular_function	transmembrane transporter activity
A	0032991	cellular_component	protein-containing complex
A	0034763	biological_process	negative regulation of transmembrane transport
A	0042956	biological_process	maltodextrin transmembrane transport
A	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
A	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
A	0055085	biological_process	transmembrane transport
A	0071702	biological_process	organic substance transport
A	0140297	molecular_function	DNA-binding transcription factor binding
A	0140359	molecular_function	ABC-type transporter activity
A	1902344	biological_process	negative regulation of maltose transport
A	1904981	biological_process	maltose transmembrane transport
A	1990060	cellular_component	maltose transport complex
A	1990154	cellular_component	enzyme IIA-maltose transporter complex
B	0000166	molecular_function	nucleotide binding
B	0005515	molecular_function	protein binding
B	0005524	molecular_function	ATP binding
B	0005886	cellular_component	plasma membrane
B	0008643	biological_process	carbohydrate transport
B	0015423	molecular_function	ABC-type maltose transporter activity
B	0015768	biological_process	maltose transport
B	0016020	cellular_component	membrane
B	0016887	molecular_function	ATP hydrolysis activity
B	0022857	molecular_function	transmembrane transporter activity
B	0032991	cellular_component	protein-containing complex
B	0034763	biological_process	negative regulation of transmembrane transport
B	0042956	biological_process	maltodextrin transmembrane transport
B	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
B	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
B	0055085	biological_process	transmembrane transport
B	0071702	biological_process	organic substance transport
B	0140297	molecular_function	DNA-binding transcription factor binding
B	0140359	molecular_function	ABC-type transporter activity
B	1902344	biological_process	negative regulation of maltose transport
B	1904981	biological_process	maltose transmembrane transport
B	1990060	cellular_component	maltose transport complex
B	1990154	cellular_component	enzyme IIA-maltose transporter complex
E	0005515	molecular_function	protein binding
E	0006974	biological_process	DNA damage response
E	0008643	biological_process	carbohydrate transport
E	0015144	molecular_function	carbohydrate transmembrane transporter activity
E	0015768	biological_process	maltose transport
E	0016020	cellular_component	membrane
E	0030288	cellular_component	outer membrane-bounded periplasmic space
E	0034219	biological_process	carbohydrate transmembrane transport
E	0034289	biological_process	detection of maltose stimulus
E	0042597	cellular_component	periplasmic space
E	0042956	biological_process	maltodextrin transmembrane transport
E	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
E	0055052	cellular_component	ATP-binding cassette (ABC) transporter complex, substrate-binding subunit-containing
E	0055085	biological_process	transmembrane transport
E	0060326	biological_process	cell chemotaxis
E	0071702	biological_process	organic substance transport
E	1901982	molecular_function	maltose binding
E	1990060	cellular_component	maltose transport complex
F	0005515	molecular_function	protein binding
F	0005886	cellular_component	plasma membrane
F	0006974	biological_process	DNA damage response
F	0015423	molecular_function	ABC-type maltose transporter activity
F	0015768	biological_process	maltose transport
F	0016020	cellular_component	membrane
F	0034763	biological_process	negative regulation of transmembrane transport
F	0042956	biological_process	maltodextrin transmembrane transport
F	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
F	0055085	biological_process	transmembrane transport
F	0071702	biological_process	organic substance transport
F	1902344	biological_process	negative regulation of maltose transport
F	1904981	biological_process	maltose transmembrane transport
F	1990060	cellular_component	maltose transport complex
F	1990154	cellular_component	enzyme IIA-maltose transporter complex
G	0005515	molecular_function	protein binding
G	0005886	cellular_component	plasma membrane
G	0015423	molecular_function	ABC-type maltose transporter activity
G	0015768	biological_process	maltose transport
G	0016020	cellular_component	membrane
G	0034763	biological_process	negative regulation of transmembrane transport
G	0042956	biological_process	maltodextrin transmembrane transport
G	0043190	cellular_component	ATP-binding cassette (ABC) transporter complex
G	0055085	biological_process	transmembrane transport
G	0071702	biological_process	organic substance transport
G	1902344	biological_process	negative regulation of maltose transport
G	1904981	biological_process	maltose transmembrane transport
G	1990060	cellular_component	maltose transport complex
G	1990154	cellular_component	enzyme IIA-maltose transporter complex

Functional Information from PROSITE/UniProt

site_id	PS01037
Number of Residues	18
Details	SBP_BACTERIAL_1 Bacterial extracellular solute-binding proteins, family 1 signature. PIAvEalSLIYNkdlLpN

Chain	Residue	Details
E	PRO107-ASN124

site_id	PS00211
Number of Residues	15
Details	ABC_TRANSPORTER_1 ABC transporters family signature. LSGGQRQRVAIGRTL

Chain	Residue	Details
A	LEU134-LEU148

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	84
Details	TOPO_DOM: Cytoplasmic => ECO:0000305

Chain	Residue	Details
G	MET1-LEU18
G	SER103-LYS123
G	LEU172-ARG204
G	ALA281-GLY296
F	LEU506-ASP514

site_id	SWS_FT_FI2
Number of Residues	120
Details	TRANSMEM: Helical => ECO:0000305

Chain	Residue	Details
G	LEU19-LEU39
G	LEU82-LEU102
G	GLY124-PHE144
G	ILE151-ALA171
G	LEU205-ALA225
G	TRP260-LEU280
F	LEU426-PRO452
F	PHE484-ASN505

site_id	SWS_FT_FI3
Number of Residues	79
Details	TOPO_DOM: Periplasmic => ECO:0000305

Chain	Residue	Details
G	ARG40-VAL81
G	ASP145-TYR150
G	ALA226-LEU259
F	ASP453-ASP483

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)