Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003723 | molecular_function | RNA binding |
| A | 0004519 | molecular_function | endonuclease activity |
| A | 0004521 | molecular_function | RNA endonuclease activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006364 | biological_process | rRNA processing |
| A | 0016180 | biological_process | snRNA processing |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0003723 | molecular_function | RNA binding |
| B | 0004519 | molecular_function | endonuclease activity |
| B | 0004521 | molecular_function | RNA endonuclease activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006364 | biological_process | rRNA processing |
| B | 0016180 | biological_process | snRNA processing |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0003723 | molecular_function | RNA binding |
| C | 0004519 | molecular_function | endonuclease activity |
| C | 0004521 | molecular_function | RNA endonuclease activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0006364 | biological_process | rRNA processing |
| C | 0016180 | biological_process | snRNA processing |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0003723 | molecular_function | RNA binding |
| D | 0004519 | molecular_function | endonuclease activity |
| D | 0004521 | molecular_function | RNA endonuclease activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0006364 | biological_process | rRNA processing |
| D | 0016180 | biological_process | snRNA processing |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 432 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 433 |
| Chain | Residue |
| A | PRO172 |
| A | ASP173 |
| A | SER269 |
| A | GLU270 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 434 |
| Chain | Residue |
| A | HIS238 |
| A | HIS240 |
| A | ARG241 |
| B | ARG368 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 435 |
| Chain | Residue |
| A | TYR189 |
| A | ARG227 |
| A | GLY340 |
| A | TYR341 |
| A | GLN378 |
| A | GLY379 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 436 |
| Chain | Residue |
| A | HIS61 |
| A | PHE223 |
| A | VAL225 |
| A | GLU226 |
| A | ARG227 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 437 |
| Chain | Residue |
| A | LYS298 |
| A | ASN301 |
| A | HIS323 |
| A | LYS326 |
| A | HIS327 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 438 |
| Chain | Residue |
| A | ARG73 |
| C | ARG424 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 439 |
| Chain | Residue |
| A | GLY318 |
| A | GLY319 |
| A | HOH459 |
| site_id | AC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 440 |
| site_id | BC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 A 441 |
| site_id | BC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 442 |
| Chain | Residue |
| A | PRO243 |
| A | ARG244 |
| B | ARG302 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 443 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 444 |
| Chain | Residue |
| A | ARG24 |
| A | LEU129 |
| A | GLY130 |
| site_id | BC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 445 |
| Chain | Residue |
| A | ASP250 |
| A | SER251 |
| A | PRO252 |
| A | ALA311 |
| A | GLY312 |
| A | GLY319 |
| A | ARG320 |
| A | HOH489 |
| site_id | BC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 446 |
| Chain | Residue |
| A | ARG25 |
| A | PHE47 |
| A | ASP48 |
| site_id | BC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 447 |
| Chain | Residue |
| A | LYS99 |
| A | PRO252 |
| A | ARG256 |
| site_id | BC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 448 |
| Chain | Residue |
| A | ARG2 |
| A | GLY426 |
| A | GLY428 |
| site_id | BC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 449 |
| Chain | Residue |
| A | PRO366 |
| A | ARG368 |
| site_id | CC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 450 |
| Chain | Residue |
| A | THR222 |
| A | PHE223 |
| A | ALA224 |
| A | SER313 |
| A | GLY314 |
| site_id | CC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 451 |
| Chain | Residue |
| A | ARG84 |
| A | LEU88 |
| A | SO4432 |
| A | HOH483 |
| D | GLU270 |
| site_id | CC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 452 |
| Chain | Residue |
| A | PRO304 |
| A | ARG333 |
| site_id | CC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 A 453 |
| Chain | Residue |
| A | HIS293 |
| A | HOH464 |
| site_id | CC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE FLC A 454 |
| Chain | Residue |
| A | GLY279 |
| A | LYS280 |
| A | ASN281 |
| A | ARG284 |
| A | HOH504 |
| B | HIS293 |
| site_id | CC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 455 |
| Chain | Residue |
| A | ASP63 |
| A | HIS64 |
| A | ASP162 |
| A | HIS400 |
| A | ZN456 |
| site_id | CC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN A 456 |
| Chain | Residue |
| A | HIS59 |
| A | HIS61 |
| A | HIS141 |
| A | ASP162 |
| A | ZN455 |
| site_id | CC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 432 |
| site_id | CC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 433 |
| Chain | Residue |
| B | ARG84 |
| B | ARG263 |
| B | HOH460 |
| site_id | DC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 434 |
| site_id | DC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 435 |
| site_id | DC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 436 |
| site_id | DC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 437 |
| Chain | Residue |
| B | TYR341 |
| B | GLY379 |
| B | HIS380 |
| B | TYR189 |
| B | ARG227 |
| B | GLY340 |
| site_id | DC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 438 |
| Chain | Residue |
| A | ARG244 |
| B | LYS298 |
| B | ASN301 |
| B | HIS323 |
| B | LYS326 |
| B | HIS327 |
| B | LEU361 |
| site_id | DC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 439 |
| site_id | DC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 B 440 |
| Chain | Residue |
| B | THR222 |
| B | PHE223 |
| B | ALA224 |
| B | SER313 |
| B | GLY314 |
| B | HOH493 |
| site_id | DC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 441 |
| Chain | Residue |
| B | ARG77 |
| D | ARG244 |
| site_id | DC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 442 |
| Chain | Residue |
| B | GLY318 |
| B | GLY319 |
| B | SO4443 |
| B | FLC455 |
| site_id | EC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 443 |
| Chain | Residue |
| B | HIS323 |
| B | SO4442 |
| site_id | EC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 444 |
| Chain | Residue |
| A | LYS280 |
| B | ARG359 |
| B | GLY362 |
| site_id | EC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 B 445 |
| site_id | EC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 446 |
| Chain | Residue |
| B | ARG2 |
| B | GLY426 |
| B | GLY428 |
| site_id | EC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 447 |
| Chain | Residue |
| B | ARG284 |
| B | VAL290 |
| site_id | EC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 448 |
| Chain | Residue |
| B | LYS99 |
| B | PRO252 |
| B | ARG256 |
| site_id | EC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 449 |
| Chain | Residue |
| B | LYS217 |
| B | ASN301 |
| B | ARG302 |
| B | ALA303 |
| B | PRO304 |
| site_id | EC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 450 |
| Chain | Residue |
| B | ARG24 |
| B | LEU129 |
| B | GLY130 |
| site_id | EC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 B 451 |
| Chain | Residue |
| B | ARG25 |
| B | PHE47 |
| B | ASP48 |
| site_id | FC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 452 |
| Chain | Residue |
| B | GLU292 |
| B | HIS293 |
| B | THR294 |
| B | ARG320 |
| B | FLC455 |
| site_id | FC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 B 453 |
| Chain | Residue |
| B | PRO172 |
| B | ASP173 |
| B | SER269 |
| B | GLU270 |
| site_id | FC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 B 454 |
| Chain | Residue |
| B | PRO243 |
| B | ARG244 |
| site_id | FC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FLC B 455 |
| Chain | Residue |
| B | GLY312 |
| B | GLY319 |
| B | ARG320 |
| B | SO4442 |
| B | SO4452 |
| site_id | FC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE FLC B 456 |
| Chain | Residue |
| A | LEU407 |
| A | LYS411 |
| B | LEU407 |
| B | LYS411 |
| B | ALA414 |
| site_id | FC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 457 |
| Chain | Residue |
| B | ASP63 |
| B | HIS64 |
| B | ASP162 |
| B | HIS400 |
| B | ZN458 |
| site_id | FC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN B 458 |
| Chain | Residue |
| B | HIS59 |
| B | HIS61 |
| B | HIS141 |
| B | ASP162 |
| B | ZN457 |
| site_id | FC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 432 |
| site_id | FC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 433 |
| Chain | Residue |
| C | ARG25 |
| C | PHE47 |
| C | ASP48 |
| site_id | GC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 C 434 |
| site_id | GC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 435 |
| Chain | Residue |
| C | PHE223 |
| C | ALA224 |
| C | SER313 |
| C | GLY314 |
| C | MET315 |
| site_id | GC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 C 436 |
| site_id | GC4 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 438 |
| site_id | GC5 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 439 |
| Chain | Residue |
| C | LYS99 |
| C | PRO252 |
| C | MET253 |
| C | ARG256 |
| site_id | GC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 C 440 |
| Chain | Residue |
| C | LYS298 |
| C | ASN301 |
| C | HIS323 |
| C | HIS327 |
| site_id | GC7 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 441 |
| Chain | Residue |
| C | ARG24 |
| C | LEU129 |
| C | GLY130 |
| site_id | GC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 442 |
| Chain | Residue |
| C | ARG84 |
| C | LEU88 |
| C | ARG263 |
| site_id | GC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 C 443 |
| Chain | Residue |
| C | TYR189 |
| C | ARG227 |
| C | TYR341 |
| C | GLY379 |
| C | HIS380 |
| site_id | HC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 444 |
| Chain | Residue |
| C | ARG2 |
| C | GLY426 |
| C | GLY428 |
| site_id | HC2 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 C 445 |
| site_id | HC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 C 446 |
| Chain | Residue |
| C | PRO172 |
| C | ASP173 |
| C | GLU270 |
| site_id | HC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 447 |
| Chain | Residue |
| C | ASP63 |
| C | HIS64 |
| C | ASP162 |
| C | HIS400 |
| site_id | HC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN C 448 |
| Chain | Residue |
| C | HIS59 |
| C | HIS61 |
| C | HIS141 |
| C | ASP162 |
| C | HIS380 |
| site_id | HC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 432 |
| Chain | Residue |
| D | TYR189 |
| D | ARG227 |
| D | GLY340 |
| D | GLY379 |
| site_id | HC7 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE SO4 D 433 |
| site_id | HC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 D 434 |
| Chain | Residue |
| D | ARG24 |
| D | ARG128 |
| D | GLY130 |
| site_id | HC9 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 435 |
| site_id | IC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 436 |
| Chain | Residue |
| D | PRO172 |
| D | ASP173 |
| D | SER269 |
| D | GLU270 |
| site_id | IC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 D 437 |
| Chain | Residue |
| D | ARG2 |
| D | LYS50 |
| D | GLY426 |
| D | GLY428 |
| site_id | IC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 438 |
| Chain | Residue |
| D | ASP63 |
| D | HIS64 |
| D | ASP162 |
| D | HIS400 |
| D | ZN439 |
| site_id | IC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ZN D 439 |
| Chain | Residue |
| D | HIS59 |
| D | HIS61 |
| D | HIS141 |
| D | ASP162 |
| D | ZN438 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 28 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | HIS59 | |
| A | HIS61 | |
| B | ASP162 | |
| B | HIS400 | |
| C | HIS59 | |
| C | HIS61 | |
| C | ASP63 | |
| C | HIS64 | |
| C | HIS141 | |
| C | ASP162 | |
| C | HIS400 | |
| D | HIS59 | |
| D | HIS61 | |
| D | ASP63 | |
| D | HIS64 | |
| D | HIS141 | |
| D | ASP162 | |
| D | HIS400 | |
| A | ASP63 | |
| A | HIS64 | |
| A | HIS141 | |
| A | ASP162 | |
| A | HIS400 | |
| B | HIS59 | |
| B | HIS61 | |
| B | ASP63 | |
| B | HIS64 | |
| B | HIS141 | |
