Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004807 | molecular_function | triose-phosphate isomerase activity |
| A | 0006096 | biological_process | glycolytic process |
| B | 0004807 | molecular_function | triose-phosphate isomerase activity |
| B | 0006096 | biological_process | glycolytic process |
| C | 0004807 | molecular_function | triose-phosphate isomerase activity |
| C | 0006096 | biological_process | glycolytic process |
| D | 0004807 | molecular_function | triose-phosphate isomerase activity |
| D | 0006096 | biological_process | glycolytic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1266 |
| Chain | Residue |
| A | ALA186 |
| A | HOH2166 |
| A | ILE187 |
| A | GLY188 |
| A | SER228 |
| A | GLY249 |
| A | GLY250 |
| A | HOH2140 |
| A | HOH2164 |
| A | HOH2165 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1266 |
| Chain | Residue |
| B | ALA186 |
| B | ILE187 |
| B | GLY188 |
| B | SER228 |
| B | GLY249 |
| B | GLY250 |
| B | HOH2126 |
| B | HOH2147 |
| B | HOH2148 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1266 |
| Chain | Residue |
| C | GLY188 |
| C | GLY227 |
| C | SER228 |
| C | GLY249 |
| C | GLY250 |
| C | HOH2098 |
| C | HOH2099 |
| C | HOH2100 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1266 |
| Chain | Residue |
| D | GLY188 |
| D | GLY227 |
| D | SER228 |
| D | GLY249 |
| D | GLY250 |
| D | HOH2103 |
| D | HOH2104 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT A 1267 |
| Chain | Residue |
| A | LYS254 |
| A | PRO255 |
| A | GLU256 |
| A | HOH2167 |
| B | ARG232 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 1268 |
| Chain | Residue |
| A | LYS170 |
| A | LYS171 |
| A | HOH2168 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 1267 |
| Chain | Residue |
| A | ARG232 |
| B | LYS254 |
| B | PRO255 |
| B | GLU256 |
| site_id | AC8 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT C 1267 |
| Chain | Residue |
| C | ARG114 |
| C | ASN121 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT A 1269 |
| Chain | Residue |
| A | LYS167 |
| A | LYS212 |
| A | HOH2169 |
| C | HOH2087 |
| site_id | BC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT B 1268 |
| Chain | Residue |
| B | LYS170 |
| B | LYS171 |
| site_id | BC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT C 1268 |
| Chain | Residue |
| C | ILE53 |
| C | ASN54 |
| C | HIS55 |
| C | LYS262 |
| C | GLU265 |
| C | HOH2012 |
| site_id | BC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT D 1267 |
| Chain | Residue |
| B | LYS167 |
| D | ARG149 |
| D | GLN197 |
| D | HOH2122 |
| site_id | BC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE ACT B 1269 |
| Chain | Residue |
| B | ARG114 |
| B | ASN121 |
| B | HOH2081 |
| B | HOH2149 |
| D | VAL156 |
| site_id | BC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT D 1268 |
| Chain | Residue |
| D | ILE53 |
| D | ASN54 |
| D | HIS55 |
| D | LYS262 |
| D | GLU265 |
| D | HOH2021 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE ACT A 1270 |
| Chain | Residue |
| A | SER52 |
| A | ILE53 |
| A | ASN54 |
| A | HIS55 |
| A | LYS262 |
| A | GLU265 |
| site_id | BC7 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 1270 |
| Chain | Residue |
| B | LYS167 |
| B | LYS212 |
| B | HOH2150 |
| B | HOH2151 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ACT B 1271 |
| Chain | Residue |
| B | SER64 |
| B | TRP65 |
| B | TYR66 |
| C | LYS33 |
| site_id | BC9 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE ACT D 1269 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT D 1270 |
| Chain | Residue |
| D | ASN230 |
| D | ARG232 |
| D | ASN233 |
| site_id | CC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE ACT A 1271 |
| Chain | Residue |
| A | LYS33 |
| A | SER64 |
| A | TRP65 |
| site_id | CC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE ACT A 1272 |
Functional Information from PROSITE/UniProt
| site_id | PS00171 |
| Number of Residues | 11 |
| Details | TIM_1 Triosephosphate isomerase active site. AYEPVWAIGTG |
| Chain | Residue | Details |
| A | ALA180-GLY190 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Electrophile |
| Chain | Residue | Details |
| A | TYR117 | |
| B | TYR117 | |
| C | TYR117 | |
| D | TYR117 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | ACT_SITE: Proton acceptor |
| Chain | Residue | Details |
| A | THR189 | |
| B | THR189 | |
| C | THR189 | |
| D | THR189 | |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | ASN31 | |
| A | LYS33 | |
| B | ASN31 | |
| B | LYS33 | |
| C | ASN31 | |
| C | LYS33 | |
| D | ASN31 | |
| D | LYS33 | |
