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1Z7C

Crystal Structure of Human Placental Lactogen

Functional Information from GO Data
ChainGOidnamespacecontents
A0005131molecular_functiongrowth hormone receptor binding
A0005179molecular_functionhormone activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005783cellular_componentendoplasmic reticulum
A0008083molecular_functiongrowth factor activity
A0031667biological_processresponse to nutrient levels
A0031904cellular_componentendosome lumen
A0031982cellular_componentvesicle
A0042531biological_processpositive regulation of tyrosine phosphorylation of STAT protein
A0045927biological_processpositive regulation of growth
A0046427biological_processpositive regulation of receptor signaling pathway via JAK-STAT
A0046872molecular_functionmetal ion binding
A0048513biological_processanimal organ development
A0060396biological_processgrowth hormone receptor signaling pathway
Functional Information from PROSITE/UniProt
site_idPS00266
Number of Residues34
DetailsSOMATOTROPIN_1 Somatotropin, prolactin and related hormones signature 1. CfSdsIpTPsnmeeTqqksnleLlrisllLieSW
ChainResidueDetails
ACYS53-TRP86

site_idPS00338
Number of Residues18
DetailsSOMATOTROPIN_2 Somatotropin, prolactin and related hormones signature 2. CFRkDMdKVEtFlrMvqC
ChainResidueDetails
ACYS165-CYS182

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsBINDING:
ChainResidueDetails
AHIS18
AGLU174

219515

PDB entries from 2024-05-08

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