1LED

STRUCTURES OF THE LECTIN IV OF GRIFFONIA SIMPLICIFOLIA AND ITS COMPLEX WITH THE LEWIS B HUMAN BLOOD GROUP DETERMINANT AT 2.0 ANGSTROMS RESOLUTION

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0030246	molecular_function	carbohydrate binding
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	CA
Number of Residues	6
Details

Chain	Residue
A	ASP131
A	TRP133
A	ASN135
A	ASP140
A	HOH329
A	HOH333

---

site_id	CHO
Number of Residues	12
Details

Chain	Residue
A	ARG48
A	TRP138
A	GLY222
A	TYR223
A	SER49
A	ASP89
A	TYR105
A	GLY107
A	PHE108
A	HIS114
A	TRP133
A	ASN135

---

site_id	MN
Number of Residues	6
Details

Chain	Residue
A	GLU129
A	ASP131
A	ASP140
A	HIS145
A	HOH305
A	HOH332

---

Functional Information from PROSITE/UniProt

site_id	PS00307
Number of Residues	7
Details	LECTIN_LEGUME_BETA Legume lectins beta-chain signature. VAVEFDT

Chain	Residue	Details
A	VAL126-THR132

---

site_id	PS00308
Number of Residues	10
Details	LECTIN_LEGUME_ALPHA Legume lectins alpha-chain signature. LPQKVRIGFS

Chain	Residue	Details
A	LEU209-SER218

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	BINDING: BINDING => ECO:0000269|PubMed:8478943

Chain	Residue	Details
A	GLU129
A	ASP131
A	TRP133
A	ASN135
A	ASP140
A	HIS145

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:8478943

Chain	Residue	Details
A	PCA1

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine; in alpha chain

Chain	Residue	Details
A	ASN5

---

site_id	SWS_FT_FI4
Number of Residues	1
Details	CARBOHYD: N-linked (GlcNAc...) asparagine

Chain	Residue	Details
A	ASN18

---