Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

1C2O

ELECTROPHORUS ELECTRICUS ACETYLCHOLINESTERASE

Functional Information from GO Data
ChainGOidnamespacecontents
A0001919biological_processregulation of receptor recycling
A0002076biological_processosteoblast development
A0003990molecular_functionacetylcholinesterase activity
A0004104molecular_functioncholinesterase activity
A0005515molecular_functionprotein binding
A0005518molecular_functioncollagen binding
A0005576cellular_componentextracellular region
A0005604cellular_componentbasement membrane
A0005615cellular_componentextracellular space
A0005635cellular_componentnuclear envelope
A0005788cellular_componentendoplasmic reticulum lumen
A0005794cellular_componentGolgi apparatus
A0005886cellular_componentplasma membrane
A0006581biological_processacetylcholine catabolic process
A0007155biological_processcell adhesion
A0007416biological_processsynapse assembly
A0008291biological_processacetylcholine metabolic process
A0009986cellular_componentcell surface
A0016020cellular_componentmembrane
A0016787molecular_functionhydrolase activity
A0017171molecular_functionserine hydrolase activity
A0019695biological_processcholine metabolic process
A0030424cellular_componentaxon
A0030425cellular_componentdendrite
A0031594cellular_componentneuromuscular junction
A0031623biological_processreceptor internalization
A0032868biological_processresponse to insulin
A0033265molecular_functioncholine binding
A0042166molecular_functionacetylcholine binding
A0042734cellular_componentpresynaptic membrane
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0043025cellular_componentneuronal cell body
A0043083cellular_componentsynaptic cleft
A0043236molecular_functionlaminin binding
A0043621molecular_functionobsolete protein self-association
A0045202cellular_componentsynapse
A0045211cellular_componentpostsynaptic membrane
A0048471cellular_componentperinuclear region of cytoplasm
A0050772biological_processpositive regulation of axonogenesis
A0050775biological_processpositive regulation of dendrite morphogenesis
A0052689molecular_functioncarboxylic ester hydrolase activity
A0060041biological_processretina development in camera-type eye
A0095500biological_processacetylcholine receptor signaling pathway
A0098552cellular_componentside of membrane
A0120162biological_processpositive regulation of cold-induced thermogenesis
B0001919biological_processregulation of receptor recycling
B0002076biological_processosteoblast development
B0003990molecular_functionacetylcholinesterase activity
B0004104molecular_functioncholinesterase activity
B0005515molecular_functionprotein binding
B0005518molecular_functioncollagen binding
B0005576cellular_componentextracellular region
B0005604cellular_componentbasement membrane
B0005615cellular_componentextracellular space
B0005635cellular_componentnuclear envelope
B0005788cellular_componentendoplasmic reticulum lumen
B0005794cellular_componentGolgi apparatus
B0005886cellular_componentplasma membrane
B0006581biological_processacetylcholine catabolic process
B0007155biological_processcell adhesion
B0007416biological_processsynapse assembly
B0008291biological_processacetylcholine metabolic process
B0009986cellular_componentcell surface
B0016020cellular_componentmembrane
B0016787molecular_functionhydrolase activity
B0017171molecular_functionserine hydrolase activity
B0019695biological_processcholine metabolic process
B0030424cellular_componentaxon
B0030425cellular_componentdendrite
B0031594cellular_componentneuromuscular junction
B0031623biological_processreceptor internalization
B0032868biological_processresponse to insulin
B0033265molecular_functioncholine binding
B0042166molecular_functionacetylcholine binding
B0042734cellular_componentpresynaptic membrane
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0043025cellular_componentneuronal cell body
B0043083cellular_componentsynaptic cleft
B0043236molecular_functionlaminin binding
B0043621molecular_functionobsolete protein self-association
B0045202cellular_componentsynapse
B0045211cellular_componentpostsynaptic membrane
B0048471cellular_componentperinuclear region of cytoplasm
B0050772biological_processpositive regulation of axonogenesis
B0050775biological_processpositive regulation of dendrite morphogenesis
B0052689molecular_functioncarboxylic ester hydrolase activity
B0060041biological_processretina development in camera-type eye
B0095500biological_processacetylcholine receptor signaling pathway
B0098552cellular_componentside of membrane
B0120162biological_processpositive regulation of cold-induced thermogenesis
C0001919biological_processregulation of receptor recycling
C0002076biological_processosteoblast development
C0003990molecular_functionacetylcholinesterase activity
C0004104molecular_functioncholinesterase activity
C0005515molecular_functionprotein binding
C0005518molecular_functioncollagen binding
C0005576cellular_componentextracellular region
C0005604cellular_componentbasement membrane
C0005615cellular_componentextracellular space
C0005635cellular_componentnuclear envelope
C0005788cellular_componentendoplasmic reticulum lumen
C0005794cellular_componentGolgi apparatus
C0005886cellular_componentplasma membrane
C0006581biological_processacetylcholine catabolic process
C0007155biological_processcell adhesion
C0007416biological_processsynapse assembly
C0008291biological_processacetylcholine metabolic process
C0009986cellular_componentcell surface
C0016020cellular_componentmembrane
C0016787molecular_functionhydrolase activity
C0017171molecular_functionserine hydrolase activity
C0019695biological_processcholine metabolic process
C0030424cellular_componentaxon
C0030425cellular_componentdendrite
C0031594cellular_componentneuromuscular junction
C0031623biological_processreceptor internalization
C0032868biological_processresponse to insulin
C0033265molecular_functioncholine binding
C0042166molecular_functionacetylcholine binding
C0042734cellular_componentpresynaptic membrane
C0042802molecular_functionidentical protein binding
C0042803molecular_functionprotein homodimerization activity
C0043025cellular_componentneuronal cell body
C0043083cellular_componentsynaptic cleft
C0043236molecular_functionlaminin binding
C0043621molecular_functionobsolete protein self-association
C0045202cellular_componentsynapse
C0045211cellular_componentpostsynaptic membrane
C0048471cellular_componentperinuclear region of cytoplasm
C0050772biological_processpositive regulation of axonogenesis
C0050775biological_processpositive regulation of dendrite morphogenesis
C0052689molecular_functioncarboxylic ester hydrolase activity
C0060041biological_processretina development in camera-type eye
C0095500biological_processacetylcholine receptor signaling pathway
C0098552cellular_componentside of membrane
C0120162biological_processpositive regulation of cold-induced thermogenesis
D0001919biological_processregulation of receptor recycling
D0002076biological_processosteoblast development
D0003990molecular_functionacetylcholinesterase activity
D0004104molecular_functioncholinesterase activity
D0005515molecular_functionprotein binding
D0005518molecular_functioncollagen binding
D0005576cellular_componentextracellular region
D0005604cellular_componentbasement membrane
D0005615cellular_componentextracellular space
D0005635cellular_componentnuclear envelope
D0005788cellular_componentendoplasmic reticulum lumen
D0005794cellular_componentGolgi apparatus
D0005886cellular_componentplasma membrane
D0006581biological_processacetylcholine catabolic process
D0007155biological_processcell adhesion
D0007416biological_processsynapse assembly
D0008291biological_processacetylcholine metabolic process
D0009986cellular_componentcell surface
D0016020cellular_componentmembrane
D0016787molecular_functionhydrolase activity
D0017171molecular_functionserine hydrolase activity
D0019695biological_processcholine metabolic process
D0030424cellular_componentaxon
D0030425cellular_componentdendrite
D0031594cellular_componentneuromuscular junction
D0031623biological_processreceptor internalization
D0032868biological_processresponse to insulin
D0033265molecular_functioncholine binding
D0042166molecular_functionacetylcholine binding
D0042734cellular_componentpresynaptic membrane
D0042802molecular_functionidentical protein binding
D0042803molecular_functionprotein homodimerization activity
D0043025cellular_componentneuronal cell body
D0043083cellular_componentsynaptic cleft
D0043236molecular_functionlaminin binding
D0043621molecular_functionobsolete protein self-association
D0045202cellular_componentsynapse
D0045211cellular_componentpostsynaptic membrane
D0048471cellular_componentperinuclear region of cytoplasm
D0050772biological_processpositive regulation of axonogenesis
D0050775biological_processpositive regulation of dendrite morphogenesis
D0052689molecular_functioncarboxylic ester hydrolase activity
D0060041biological_processretina development in camera-type eye
D0095500biological_processacetylcholine receptor signaling pathway
D0098552cellular_componentside of membrane
D0120162biological_processpositive regulation of cold-induced thermogenesis
Functional Information from PROSITE/UniProt
site_idPS00122
Number of Residues16
DetailsCARBOXYLESTERASE_B_1 Carboxylesterases type-B serine active site. FGGdpmsVtLfGeSAG
ChainResidueDetails
APHE190-GLY205

site_idPS00941
Number of Residues11
DetailsCARBOXYLESTERASE_B_2 Carboxylesterases type-B signature 2. EDCLYLNVWtP
ChainResidueDetails
AGLU94-PRO104

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues4
DetailsACT_SITE: Acyl-ester intermediate
ChainResidueDetails
ASER203
BSER203
CSER203
DSER203

site_idSWS_FT_FI2
Number of Residues8
DetailsACT_SITE: Charge relay system
ChainResidueDetails
AGLU334
AHIS447
BGLU334
BHIS447
CGLU334
CHIS447
DGLU334
DHIS447

site_idSWS_FT_FI3
Number of Residues4
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN265
BASN265
CASN265
DASN265

site_idSWS_FT_FI4
Number of Residues8
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine
ChainResidueDetails
AASN350
AASN464
BASN350
BASN464
CASN350
CASN464
DASN350
DASN464

218853

PDB entries from 2024-04-24

PDB statisticsPDBj update infoContact PDBjnumon