4P0W

Human farnesyl diphosphate synthase in complex with Arenarone and zoledronate

Experimental procedure

Experimental method	SINGLE WAVELENGTH
Source type	SYNCHROTRON
Source details	APS BEAMLINE 21-ID-F
Synchrotron site	APS
Beamline	21-ID-F
Temperature [K]	298
Detector technology	CCD
Collection date	2013-12-13
Detector	MARMOSAIC 225 mm CCD
Wavelength(s)	0.97872
Spacegroup name	P 41 21 2
Unit cell lengths	111.239, 111.239, 67.292
Unit cell angles	90.00, 90.00, 90.00

Refinement procedure

Resolution	57.580 - 2.406
R-factor	0.2077
Rwork	0.204
R-free	0.28940
RMSD bond length	0.017
RMSD bond angle	1.791
Refinement software	REFMAC (5.8.0069)

Data quality characteristics

	Overall
Low resolution limit [Å]	57.580
High resolution limit [Å]	2.400
Number of reflections	16815
<I/σ(I)>	30.79
Completeness [%]	99.7
Redundancy	26

Crystallization Conditions

crystal ID	method	pH	temperature	details
1	VAPOR DIFFUSION, HANGING DROP	5	293	1.2M sodium potassium phosphate, 25% glycerol