4P2Q
| Crystal structure of the 5cc7 TCR in complex with 5c2/I-Ek | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5c2 peptide, 5cc7 T-cell receptor alpha chain, ... | Authors: | Birnbaum, M.E, Ozkan, E, Garcia, K.C. | Deposit date: | 2014-03-04 | Release date: | 2014-05-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Deconstructing the Peptide-MHC Specificity of T Cell Recognition. Cell, 157, 2014
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4P2R
| Crystal structure of the 5cc7 TCR in complex with 5c1/I-Ek | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 5c1 peptide, 5cc7 T-cell receptor alpha chain, ... | Authors: | Birnbaum, M.E, Ozkan, E, Garcia, K.C. | Deposit date: | 2014-03-04 | Release date: | 2014-05-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (3.295 Å) | Cite: | Deconstructing the Peptide-MHC Specificity of T Cell Recognition. Cell, 157, 2014
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4P2O
| Crystal structure of the 2B4 TCR in complex with 2A/I-Ek | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2A peptide, 2B4 T-cell receptor alpha chain, ... | Authors: | Birnbaum, M.E, Ozkan, E, Garcia, K.C. | Deposit date: | 2014-03-04 | Release date: | 2014-05-21 | Last modified: | 2023-12-27 | Method: | X-RAY DIFFRACTION (2.603 Å) | Cite: | Deconstructing the Peptide-MHC Specificity of T Cell Recognition. Cell, 157, 2014
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4NHU
| The M33 TCR p3M33l/H-2 Ld Complex | Descriptor: | 2C m33 alpha VmCh chimera, 2C m33 beta VmCh chimera, H-2 class I histocompatibility antigen, ... | Authors: | Birnbaum, M.E, Adams, J.J, Garcia, K.C. | Deposit date: | 2013-11-05 | Release date: | 2015-05-06 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Interrogating TCR Signal Strength and Cross-Reactivity by Yeast Display of pMHC To be Published
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4N0C
| 42F3 TCR pCPE3/H-2Ld complex | Descriptor: | 42F3 VmCh alpha, 42F3 VmCh beta, H-2 class I histocompatibility antigen, ... | Authors: | Birnbaum, M.E, Adams, J.J, Garcia, K.C. | Deposit date: | 2013-10-01 | Release date: | 2015-08-19 | Last modified: | 2018-09-26 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity. Nat. Immunol., 17, 2016
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4MXQ
| 42F3 TCR pCPC5/H-2Ld Complex | Descriptor: | 42F3 alpha VmVh chimera, 42F3 beta VmVh chimera, H-2 class I histocompatibility antigen, ... | Authors: | Birnbaum, M.E, Adams, J.J, Garcia, K.C. | Deposit date: | 2013-09-26 | Release date: | 2015-08-19 | Last modified: | 2018-09-26 | Method: | X-RAY DIFFRACTION (2.596 Å) | Cite: | Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity. Nat. Immunol., 17, 2016
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4MVB
| 42F3 pCPB7/H-2Ld Complex | Descriptor: | 42F3 alpha VmCh, 42F3 beta VmCh, H-2 class I histocompatibility antigen, ... | Authors: | Birnbaum, M.E, Adams, J.J, Garcia, K.C. | Deposit date: | 2013-09-23 | Release date: | 2015-08-19 | Last modified: | 2018-09-26 | Method: | X-RAY DIFFRACTION (3.088 Å) | Cite: | Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity. Nat. Immunol., 17, 2016
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4N5E
| 42F3 TCR pCPA12/H-2Ld complex | Descriptor: | 42F3 alpha VmCh, 42F3 beta VmCh, H-2 class I histocompatibility antigen, ... | Authors: | Birnbaum, M.E, Adams, J.J, Garcia, K.C. | Deposit date: | 2013-10-09 | Release date: | 2015-08-19 | Last modified: | 2018-09-26 | Method: | X-RAY DIFFRACTION (3.059 Å) | Cite: | Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity. Nat. Immunol., 17, 2016
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4MS8
| 42F3 TCR pCPB9/H-2Ld Complex | Descriptor: | 42F3 alpha, 42F3 beta, H-2 class I histocompatibility antigen, ... | Authors: | Birnbaum, M.E, Adams, J.J, Garcia, K.C. | Deposit date: | 2013-09-18 | Release date: | 2014-09-24 | Last modified: | 2018-09-26 | Method: | X-RAY DIFFRACTION (1.922 Å) | Cite: | Structural interplay between germline interactions and adaptive recognition determines the bandwidth of TCR-peptide-MHC cross-reactivity. Nat. Immunol., 17, 2016
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6MP0
| Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with the TRP1-M9 peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TRP1-M9 peptide, Beta-2-microglobulin,H-2 class I histocompatibility antigen, ... | Authors: | Clancy-Thompson, E, Devlin, C.A, Birnbaum, M.E, Dougan, S.K. | Deposit date: | 2018-10-05 | Release date: | 2018-11-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+T Cell-Effector Responses. Cancer Immunol Res, 6, 2018
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3LB6
| The structure of IL-13 in complex with IL-13Ralpha2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, Interleukin-13, ... | Authors: | Lupardus, P.J, Garcia, K.C, Birnbaum, M.E. | Deposit date: | 2010-01-07 | Release date: | 2010-03-16 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Molecular basis for shared cytokine recognition revealed in the structure of an unusually high affinity complex between IL-13 and IL-13Ralpha2. Structure, 18, 2010
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6MP1
| Crystal structures of the murine class I major histocompatibility complex H-2Db in complex with the mutant TRP1-K8 peptide | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, TRP1-K8 peptide, Beta-2-microglobulin,H-2 class I histocompatibility antigen, ... | Authors: | Clancy-Thompson, E, Devlin, C.A, Birnbaum, M.E, Dougan, S.K. | Deposit date: | 2018-10-05 | Release date: | 2018-11-07 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.211 Å) | Cite: | Altered Binding of Tumor Antigenic Peptides to MHC Class I Affects CD8+T Cell-Effector Responses. Cancer Immunol Res, 6, 2018
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6BGA
| 2B4 I-Ek TCR-MHC complex with affinity-enhancing Velcro peptide | Descriptor: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2B4 peptide,MHC I-Ek B chain, ... | Authors: | Gee, M.H, Sibener, L.V, Birnbaum, M.E, Jude, K.M, Garcia, K.C. | Deposit date: | 2017-10-27 | Release date: | 2018-07-18 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.307 Å) | Cite: | Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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5EO9
| Crystal Structure of the complex of Dpr6 Domain 1 bound to DIP-alpha Domain 1+2 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CG32791, isoform A, ... | Authors: | Ozkan, E, Zinn, K, Garcia, K.C. | Deposit date: | 2015-11-10 | Release date: | 2016-01-06 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.2988 Å) | Cite: | Control of Synaptic Connectivity by a Network of Drosophila IgSF Cell Surface Proteins. Cell, 163, 2015
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6BJ8
| TCR55 in complex with Pep20/HLA-B35 | Descriptor: | Beta-2-microglobulin, GLYCEROL, HLA class I histocompatibility antigen, ... | Authors: | Jude, K.M, Sibener, L.V, Yang, X, Garcia, K.C. | Deposit date: | 2017-11-05 | Release date: | 2018-07-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding. Cell, 174, 2018
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6BJ3
| TCR55 in complex with HIV(Pol448-456)/HLA-B35 | Descriptor: | 1,2-ETHANEDIOL, Beta-2-microglobulin, HIV Pol B35 peptide, ... | Authors: | Jude, K.M, Sibener, L.V, Garcia, K.C. | Deposit date: | 2017-11-03 | Release date: | 2018-07-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.898 Å) | Cite: | Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding. Cell, 174, 2018
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6BJ2
| TCR589 in complex with HIV(Pol448-456)/HLA-B35 | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Beta-2-microglobulin, ... | Authors: | Jude, K.M, Sibener, L.V, Garcia, K.C. | Deposit date: | 2017-11-03 | Release date: | 2018-07-25 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Isolation of a Structural Mechanism for Uncoupling T Cell Receptor Signaling from Peptide-MHC Binding. Cell, 174, 2018
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3TJH
| 42F3-p3A1/H2-Ld complex | Descriptor: | 42F3 alpha, 42F3 beta, H2-Ld SBM2, ... | Authors: | Adams, J.J, Kruse, A, Kranz, D.M, Garcia, K.C. | Deposit date: | 2011-08-24 | Release date: | 2011-12-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.12 Å) | Cite: | T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex. Immunity, 35, 2011
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3TPU
| 42F3 p5E8/H2-Ld complex | Descriptor: | 1,2-ETHANEDIOL, 42F3 alpha, 42F3 beta, ... | Authors: | Adams, J.J, Kranz, D.M, Garcia, K.C. | Deposit date: | 2011-09-08 | Release date: | 2011-12-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex. Immunity, 35, 2011
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3TFK
| 42F3-p4B10/H2-Ld | Descriptor: | 42F3 alpha, 42F3 beta, H2-Ld SBM2, ... | Authors: | Adams, J.J, Kranz, D.M, Garcia, K.C. | Deposit date: | 2011-08-15 | Release date: | 2011-12-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.753 Å) | Cite: | T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex. Immunity, 35, 2011
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3TF7
| 42F3 QL9/H2-Ld complex | Descriptor: | 42F3 Mut7 scFv (42F3 alpha chain, linker, 42F3 beta chain), ... | Authors: | Adams, J.J, Kranz, D.M, Garcia, K.C. | Deposit date: | 2011-08-15 | Release date: | 2011-12-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | T cell receptor signaling is limited by docking geometry to peptide-major histocompatibility complex. Immunity, 35, 2011
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