6BGA

2B4 I-Ek TCR-MHC complex with affinity-enhancing Velcro peptide

Summary for 6BGA

• Entry DOI: 10.2210/pdb6bga/pdb
• Descriptor: H-2 class II histocompatibility antigen, E-K alpha chain, 2B4 peptide,MHC I-Ek B chain, T cell receptor 2B4 alpha chain, ... (10 entities in total)
• Functional Keywords: complex, engineered peptide, immune system
• Biological source: Mus musculus (Mouse); More
• Total number of polymer chains: 5
• Total formula weight: 106083.67

Authors

Gee, M.H.,Sibener, L.V.,Birnbaum, M.E.,Jude, K.M.,Garcia, K.C. (deposition date: 2017-10-27, release date: 2018-07-18, Last modification date: 2023-10-04)

• Primary citation: Gee, M.H.,Sibener, L.V.,Birnbaum, M.E.,Jude, K.M.,Yang, X.,Fernandes, R.A.,Mendoza, J.L.,Glassman, C.R.,Garcia, K.C.; Stress-testing the relationship between T cell receptor/peptide-MHC affinity and cross-reactivity using peptide velcro.; Proc. Natl. Acad. Sci. U.S.A., 115:E7369-E7378, 2018; PubMed: 30021852; DOI: 10.1073/pnas.1802746115

Experimental method

X-RAY DIFFRACTION (2.307 Å)