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2KOR
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BU of 2kor by Molmil
NMR solution structures of 2-octenoyl-ACP from Streptomyces coelicolor Fatty Acid Synthase
Descriptor: Acyl carrier protein, S-[2-[3-[[(2S)-2-hydroxy-3,3-dimethyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (E)-oct-2-enethioate
Authors:Ploskon, E, Arthur, C.J, Crump, M.P.
Deposit date:2009-09-29
Release date:2010-08-18
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Recognition of intermediate functionality by acyl carrier protein over a complete cycle of fatty acid biosynthesis
Chem.Biol., 17, 2010
2KOQ
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BU of 2koq by Molmil
NMR solution structures of 3-hydroxyoctanoyl-ACP from Streptomyces coelicolor Fatty Acid Synthase
Descriptor: Acyl carrier protein, S-[2-[3-[[(2S)-2-hydroxy-3,3-dimethyl-4-phosphonooxy-butanoyl]amino]propanoylamino]ethyl] (3R)-3-hydroxyoctanethioate
Authors:Ploskon, E, Arthur, C.J, Kanari, A.J, Crump, M.P.
Deposit date:2009-09-29
Release date:2010-08-18
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Recognition of intermediate functionality by acyl carrier protein over a complete cycle of fatty acid biosynthesis
Chem.Biol., 17, 2010
2KOO
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BU of 2koo by Molmil
NMR solution structures of hexanoyl-ACP from the Streptomyces coelicolor Fatty Acid Synthase
Descriptor: Acyl carrier protein, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] hexanethioate
Authors:Ploskon, E, Arthur, C.J, Crump, M.P.
Deposit date:2009-09-29
Release date:2010-08-18
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Recognition of intermediate functionality by acyl carrier protein over a complete cycle of fatty acid biosynthesis
Chem.Biol., 17, 2010
2KOS
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BU of 2kos by Molmil
NMR solution structures of octanoyl-ACP from Streptomyces coelicolor Fatty Acid Synthase
Descriptor: Acyl carrier protein, S-[2-({N-[(2S)-2-hydroxy-3,3-dimethyl-4-(phosphonooxy)butanoyl]-beta-alanyl}amino)ethyl] octanethioate
Authors:Ploskon, E, Arthur, C, Crump, M.P.
Deposit date:2009-09-29
Release date:2010-08-18
Last modified:2022-03-16
Method:SOLUTION NMR
Cite:Recognition of intermediate functionality by acyl carrier protein over a complete cycle of fatty acid biosynthesis
Chem.Biol., 17, 2010
4CW4
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BU of 4cw4 by Molmil
Crystal structure of the noncanonical ketosynthase FabY from P. aeruginosa
Descriptor: BETA-KETOACYL SYNTHASE, CHLORIDE ION, SULFATE ION
Authors:Bukhari, H.S.T, Jakob, R.P, Maier, T.
Deposit date:2014-04-01
Release date:2014-12-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.349 Å)
Cite:Evolutionary Origins of the Multienzyme Architecture of Giant Fungal Fatty Acid Synthase.
Structure, 22, 2014
5BP1
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BU of 5bp1 by Molmil
Condensing di-domain (KS-AT) of a mycocerosic acid synthase-like (MAS-like) PKS
Descriptor: Mycocerosic acid synthase
Authors:Jakob, R.P, Herbst, D.A, Zaehringer, F, Maier, T.
Deposit date:2015-05-27
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.203 Å)
Cite:Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases.
Nature, 531, 2016
5BP2
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BU of 5bp2 by Molmil
Dehydratase domain (DH) of a mycocerosic acid synthase-like (MAS-like) PKS, crystal form 1
Descriptor: 1,2-ETHANEDIOL, CHLORIDE ION, GLYCEROL, ...
Authors:Herbst, D.A, Jakob, P.R, Zaehringer, F, Maier, T.
Deposit date:2015-05-27
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases.
Nature, 531, 2016
5BP3
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BU of 5bp3 by Molmil
Dehydratase domain (DH) of a mycocerosic acid synthase-like (MAS-like) PKS, crystal form 2
Descriptor: 1,2-ETHANEDIOL, Mycocerosic acid synthase-like polyketide synthase
Authors:Herbst, D.A, Jakob, P.R, Zaehringer, F, Maier, T.
Deposit date:2015-05-27
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (1.45 Å)
Cite:Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases.
Nature, 531, 2016
5BP4
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BU of 5bp4 by Molmil
Modifying region (DH-ER-KR) of a mycocerosic acid synthase-like (MAS-like) PKS
Descriptor: Mycocerosic acid synthase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE
Authors:Herbst, D.A, Jakob, P.R, Zaehringer, F, Maier, T.
Deposit date:2015-05-27
Release date:2016-03-09
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (3.75 Å)
Cite:Mycocerosic acid synthase exemplifies the architecture of reducing polyketide synthases.
Nature, 531, 2016
2ML8
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BU of 2ml8 by Molmil
NMR structure of Saccharomyces cerevisiae Acyl Carrier Protein.
Descriptor: Fatty acid synthase subunit alpha
Authors:Wider, G, Perez, D.R, Leibundgut, M.
Deposit date:2014-02-20
Release date:2015-02-25
Last modified:2024-05-01
Method:SOLUTION NMR
Cite:NMR structure of Saccharomyces cerevisiae Acyl Carrier Protein
To be published
3D6X
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BU of 3d6x by Molmil
Crystal structure of Campylobacter jejuni FabZ
Descriptor: (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase
Authors:Yokoyama, T, Yeo, H.J.
Deposit date:2008-05-20
Release date:2009-05-05
Last modified:2023-11-15
Method:X-RAY DIFFRACTION (2.59 Å)
Cite:Campylobacter jejuni fatty acid synthase II: structural and functional analysis of beta-hydroxyacyl-ACP dehydratase (FabZ).
Biochem.Biophys.Res.Commun., 380, 2009
1EK4
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BU of 1ek4 by Molmil
BETA-KETOACYL [ACYL CARRIER PROTEIN] SYNTHASE I IN COMPLEX WITH DODECANOIC ACID TO 1.85 RESOLUTION
Descriptor: BETA-KETOACYL [ACYL CARRIER PROTEIN] SYNTHASE I, LAURIC ACID
Authors:Olsen, J.G, Kadziola, A, Siggaard-Andersen, M, von Wettstein-Knowles, P, Larsen, S.
Deposit date:2000-03-06
Release date:2001-04-11
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structures of beta-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery.
Structure, 9, 2001
4YX6
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BU of 4yx6 by Molmil
Architectural hierarchy of trans-acting enoyl reductases from polyunsaturated fatty acid and trans-AT polyketide synthases
Descriptor: CALCIUM ION, FLAVIN MONONUCLEOTIDE, Omega-3 polyunsaturated fatty acid synthase subunit PfaD
Authors:Till, M, Race, P.R.
Deposit date:2015-03-22
Release date:2016-04-13
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Architectural hierarchy of trans-acting enoyl reductases from polyunsaturated fatty acid and trans-AT polyketide synthases
To Be Published
1F91
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BU of 1f91 by Molmil
BETA-KETOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I IN COMPLEX WITH C10 FATTY ACID SUBSTRATE
Descriptor: BETA-KETOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, DECANOIC ACID, HYDROXIDE ION
Authors:Olsen, J.G, Kadziola, A, Wettstein-Knowles, P.V, Siggaard-Andersen, M, Larsen, S.
Deposit date:2000-07-06
Release date:2001-04-11
Last modified:2021-11-03
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structures of beta-ketoacyl-acyl carrier protein synthase I complexed with fatty acids elucidate its catalytic machinery.
Structure, 9, 2001
1W0I
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BU of 1w0i by Molmil
Arabidopsis thaliana Mitochondrial KAS
Descriptor: 3-OXOACYL CARRIER PROTEIN SYNTHASE, POTASSIUM ION, SULFATE ION
Authors:Olsen, J.G, Rasmussen, A.V, von Wettstein-Knowles, P, Henriksen, A.
Deposit date:2004-06-04
Release date:2004-11-10
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Structure of the mitochondrial beta-ketoacyl-[acyl carrier protein] synthase from Arabidopsis and its role in fatty acid synthesis.
FEBS Lett., 577, 2004
2BYY
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BU of 2byy by Molmil
E.coli KAS I H298E Mutation
Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, AMMONIUM ION
Authors:Olsen, J.G, von Wettstein-Knowles, P, Henriksen, A.
Deposit date:2005-08-09
Release date:2006-02-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases.
FEBS J., 273, 2006
2BZ4
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BU of 2bz4 by Molmil
structure of E.coli KAS I H298Q mutant
Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, AMMONIUM ION, SULFATE ION
Authors:Olsen, J.G, von Wettstein-Knowles, P, Henriksen, A.
Deposit date:2005-08-10
Release date:2006-02-01
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases.
FEBS J., 273, 2006
2BYW
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BU of 2byw by Molmil
Structure of Escherichia coli beta-ketoacyl (acyl carrier protein) synthase I LYS328ALA mutant
Descriptor: 3-OXOACYL-[ACYL-CARRIER-PROTEIN] SYNTHASE I, AMMONIUM ION
Authors:Olsen, J.G, von Wettstein-Knowles, P, Henriksen, A.
Deposit date:2005-08-09
Release date:2005-09-09
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Fatty acid synthesis. Role of active site histidines and lysine in Cys-His-His-type beta-ketoacyl-acyl carrier protein synthases.
FEBS J., 273, 2006
2CNR
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BU of 2cnr by Molmil
Structural studies on the interaction of ScFAS ACP with ACPS
Descriptor: ACYL CARRIER PROTEIN
Authors:Pottage, K, Williams, C, Crump, M.P.
Deposit date:2006-05-23
Release date:2007-06-05
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Structure and Malonyl Coa-Acp Transacylase Binding of Streptomyces Coelicolor Fatty Acid Synthase Acyl Carrier Protein.
Acs Chem.Biol., 4, 2009
7WA9
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BU of 7wa9 by Molmil
Crystal structure of MSMEG_5634 from Mycobacterium smegmatis
Descriptor: MSMEG_5634
Authors:Wang, Z, Zhang, W.
Deposit date:2021-12-12
Release date:2022-10-19
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:A Novel Acyl-AcpM-Binding Protein Confers Intrinsic Sensitivity to Fatty Acid Synthase Type II Inhibitors in Mycobacterium smegmatis
Front Microbiol, 13, 2022
6LKC
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BU of 6lkc by Molmil
Crystal structure of PfaD from Shewanella piezotolerans in complex with FMN
Descriptor: CALCIUM ION, FLAVIN MONONUCLEOTIDE, GLYCEROL, ...
Authors:Zhang, M.L, Li, Q, Meng, S.S, Guo, L.J, He, L, Huang, J.Z, Li, L, Zhang, H.D.
Deposit date:2019-12-19
Release date:2020-12-23
Last modified:2023-11-22
Method:X-RAY DIFFRACTION (1.998 Å)
Cite:Structural Insights into the Trans -Acting Enoyl Reductase in the Biosynthesis of Long-Chain Polyunsaturated Fatty Acids in Shewanella piezotolerans .
J.Agric.Food Chem., 69, 2021
4CW5
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BU of 4cw5 by Molmil
Crystal structure of the enoyl reductase domain of DfnA from Bacillus amyloliquefaciens
Descriptor: DFNA, FLAVIN MONONUCLEOTIDE
Authors:Jakob, R.P, Buhkari, H.S.T, Maier, T.
Deposit date:2014-04-01
Release date:2014-12-17
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Evolutionary Origins of the Multienzyme Architecture of Giant Fungal Fatty Acid Synthase.
Structure, 22, 2014
4Z49
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BU of 4z49 by Molmil
Homo Sapiens Fatty Acid Synthetase, Thioesterase Domain at 1.7 Angstroms Resolution
Descriptor: Fatty acid synthase, POTASSIUM ION
Authors:Spraggon, G.
Deposit date:2015-04-01
Release date:2016-03-16
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Estimation of Hydrogen-Exchange Protection Factors from MD Simulation Based on Amide Hydrogen Bonding Analysis.
J.Chem.Inf.Model., 55, 2015
3E53
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BU of 3e53 by Molmil
Crystal structure of N-terminal domain of a Fatty Acyl AMP Ligase FAAL28 from Mycobacterium tuberculosis
Descriptor: FATTY-ACID-CoA LIGASE FADD28
Authors:Goyal, A, Rajakumara, E, Yousuf, M, Sankaranarayanan, R.
Deposit date:2008-08-13
Release date:2009-01-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Mechanistic and functional insights into fatty acid activation in Mycobacterium tuberculosis.
Nat.Chem.Biol., 5, 2009
8VD9
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BU of 8vd9 by Molmil
Crystal structure of Bacillus subtilis FabHA, beta-ketoacyl carrier protein synthase III
Descriptor: 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Beta-ketoacyl-[acyl-carrier-protein] synthase III 1
Authors:Radka, C.D, Rock, C.O.
Deposit date:2023-12-14
Release date:2024-02-14
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Crystal structures of the fatty acid biosynthesis initiation enzymes in Bacillus subtilis.
J.Struct.Biol., 216, 2024

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PDB entries from 2024-05-15

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