6QNN
 
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6QNP
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6E5N
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1B89
 | | CLATHRIN HEAVY CHAIN PROXIMAL LEG SEGMENT (BOVINE) | | Descriptor: | PROTEIN (CLATHRIN HEAVY CHAIN) | | Authors: | Ybe, J.A, Brodsky, F.M, Hofmann, K, Lin, K, Liu, S.-H, Chen, L, Earnest, T.N, Fletterick, R.J, Hwang, P.K. | | Deposit date: | 1999-05-27 | | Release date: | 1999-06-04 | | Last modified: | 2024-10-30 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Clathrin self-assembly is mediated by a tandemly repeated superhelix.
Nature, 399, 1999
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1XI4
 | | Clathrin D6 Coat | | Descriptor: | Clathrin heavy chain, Clathrin light chain A | | Authors: | Fotin, A, Cheng, Y, Sliz, P, Grigorieff, N, Harrison, S.C, Kirchhausen, T, Walz, T. | | Deposit date: | 2004-09-21 | | Release date: | 2004-11-02 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (7.9 Å) | | Cite: | Molecular model for a complete clathrin lattice from electron cryomicroscopy
Nature, 432, 2004
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3IYV
 | | Clathrin D6 coat as full-length Triskelions | | Descriptor: | Clathrin heavy chain, Clathrin light chain A | | Authors: | Johnson, G.T, Fotin, A, Cheng, Y, Sliz, P, Grigorieff, N, Harrison, S.C, Kirchhausen, T, Walz, T. | | Deposit date: | 2010-06-17 | | Release date: | 2010-07-21 | | Last modified: | 2024-02-21 | | Method: | ELECTRON MICROSCOPY (7.9 Å) | | Cite: | Molecular model for a complete clathrin lattice from electron cryomicroscopy.
Nature, 432, 2004
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6SCT
 | | Cryo-EM structure of the consensus triskelion hub of the clathrin coat complex | | Descriptor: | Clathrin heavy chain, Clathrin light chain | | Authors: | Morris, K.L, Cameron, A.D, Sessions, R, Smith, C.J. | | Deposit date: | 2019-07-25 | | Release date: | 2019-10-02 | | Last modified: | 2025-07-09 | | Method: | ELECTRON MICROSCOPY (4.69 Å) | | Cite: | Cryo-EM of multiple cage architectures reveals a universal mode of clathrin self-assembly.
Nat.Struct.Mol.Biol., 26, 2019
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1XI5
 | | Clathrin D6 coat with auxilin J-domain | | Descriptor: | Auxilin J-domain, Clathrin heavy chain | | Authors: | Fotin, A, Cheng, Y, Grigorieff, N, Walz, T, Harrison, S.C, Kirchhausen, T. | | Deposit date: | 2004-09-21 | | Release date: | 2004-11-02 | | Last modified: | 2024-03-13 | | Method: | ELECTRON MICROSCOPY (12 Å) | | Cite: | Structure of an auxilin-bound clathrin coat and its implications for the mechanism of uncoating
Nature, 432, 2004
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3LVH
 | | Crystal structure of a clathrin heavy chain and clathrin light chain complex | | Descriptor: | Clathrin heavy chain 1, Clathrin light chain B | | Authors: | Wilbur, J.D, Hwang, P.K, Ybe, J.A, Lane, M, Sellers, B.D, Jacobson, M.P, Fletterick, R.J, Brodsky, F.M. | | Deposit date: | 2010-02-20 | | Release date: | 2010-06-09 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (9 Å) | | Cite: | Conformation switching of clathrin light chain regulates clathrin lattice assembly.
Dev.Cell, 18, 2010
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3LVG
 | | Crystal structure of a clathrin heavy chain and clathrin light chain complex | | Descriptor: | Clathrin heavy chain 1, Clathrin light chain B | | Authors: | Wilbur, J.D, Hwang, P.K, Ybe, J.A, Lane, M, Sellers, B.D, Jacobson, M.P, Fletterick, R.J, Brodsky, F.M. | | Deposit date: | 2010-02-20 | | Release date: | 2010-06-09 | | Last modified: | 2024-02-21 | | Method: | X-RAY DIFFRACTION (7.94 Å) | | Cite: | Conformation switching of clathrin light chain regulates clathrin lattice assembly.
Dev.Cell, 18, 2010
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6YAI
 | | Clathrin with bound beta2 appendage of AP2 | | Descriptor: | AP-2 complex subunit beta, Clathrin heavy chain, Clathrin light chain | | Authors: | Kovtun, O, Kane Dickson, V, Kelly, B.T, Owen, D, Briggs, J.A.G. | | Deposit date: | 2020-03-12 | | Release date: | 2020-07-29 | | Last modified: | 2024-05-22 | | Method: | ELECTRON MICROSCOPY (9.2 Å) | | Cite: | Architecture of the AP2/clathrin coat on the membranes of clathrin-coated vesicles.
Sci Adv, 6, 2020
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3QIL
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6WCJ
 | | Asymmetric vertex of the clathrin minicoat cage | | Descriptor: | Clathrin heavy chain 1, Clathrin light chain B | | Authors: | Paraan, M, Mendez, J, Sharum, S, Kurtin, D, He, H, Stagg, S. | | Deposit date: | 2020-03-30 | | Release date: | 2020-08-19 | | Last modified: | 2024-03-06 | | Method: | ELECTRON MICROSCOPY (6.3 Å) | | Cite: | The structures of natively assembled clathrin-coated vesicles.
Sci Adv, 6, 2020
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4G55
 | | Clathrin terminal domain complexed with pitstop 2 | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Clathrin heavy chain 1, ... | | Authors: | Bulut, H, Von Kleist, L, Saenger, W, Haucke, V. | | Deposit date: | 2012-07-17 | | Release date: | 2012-08-01 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.69 Å) | | Cite: | Role of the clathrin terminal domain in regulating coated pit dynamics revealed by small molecule inhibition.
Cell(Cambridge,Mass.), 146, 2011
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5M5V
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5M5U
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1BPO
 | | CLATHRIN HEAVY-CHAIN TERMINAL DOMAIN AND LINKER | | Descriptor: | PROTEIN (CLATHRIN) | | Authors: | Harr, E.T, Musacchio, A, Harrison, S.C, Kirchhausen, T. | | Deposit date: | 1998-08-11 | | Release date: | 1998-12-16 | | Last modified: | 2023-12-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | Atomic structure of clathrin: a beta propeller terminal domain joins an alpha zigzag linker.
Cell(Cambridge,Mass.), 95, 1998
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2XZG
 | | Clathrin Terminal Domain Complexed with Pitstop 1 | | Descriptor: | 2-(4-AMINOBENZYL)-1,3-DIOXO-2,3-DIHYDRO-1H-BENZO[DE]ISOQUINOLINE-5-SULFONATE, ACETATE ION, CLATHRIN HEAVY CHAIN 1, ... | | Authors: | Bulut, H, Von Kleist, L, Saenger, W, Haucke, V. | | Deposit date: | 2010-11-25 | | Release date: | 2011-08-17 | | Last modified: | 2023-12-20 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Role of the Clathrin Terminal Domain in Regulating Coated Pit Dynamics Revealed by Small Molecule Inhibition.
Cell(Cambridge,Mass.), 146, 2011
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9C0Y
 | | Clathrin terminal domain complexed with Pitstop 2c | | Descriptor: | 1,2-ETHANEDIOL, ACETATE ION, Clathrin heavy chain 1, ... | | Authors: | Bulut, H, Horatscheck, A, Krauss, M, Santos, K.F, McCluskey, A, Wahl, C.W, Nazare, M, Haucke, V. | | Deposit date: | 2024-05-28 | | Release date: | 2024-06-26 | | Last modified: | 2025-05-14 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Next-generation small molecule inhibitors of clathrin function acutely inhibit endocytosis.
Structure, 33, 2025
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9C0Z
 | | Clathrin terminal domain complexed with pitstop 2d | | Descriptor: | 1,2-ETHANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, ACETATE ION, ... | | Authors: | Bulut, H, Horatscheck, A, Krauss, M, Santos, K.F, McCluskey, A, Wahl, C.W, Nazare, M, Haucke, V. | | Deposit date: | 2024-05-28 | | Release date: | 2024-06-26 | | Last modified: | 2025-05-14 | | Method: | X-RAY DIFFRACTION (1.51 Å) | | Cite: | Next-generation small molecule inhibitors of clathrin function acutely inhibit endocytosis.
Structure, 33, 2025
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9EXG
 | | Crystal structure of Yeast Clathrin Heavy Chain N-terminal domain bound to Epsin-2 peptide (LIDL) | | Descriptor: | Clathrin heavy chain, Epsin-2, GLYCEROL, ... | | Authors: | Defelipe, L.A, Bento, I, Garcia Alai, M.M. | | Deposit date: | 2024-04-08 | | Release date: | 2024-11-13 | | Last modified: | 2024-11-27 | | Method: | X-RAY DIFFRACTION (1.744 Å) | | Cite: | Subtleties in Clathrin heavy chain binding boxes provide selectivity among adaptor proteins of budding yeast.
Nat Commun, 15, 2024
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9EX5
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9EYT
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4UQI
 | | AP2 controls clathrin polymerization with a membrane-activated switch | | Descriptor: | AP-2 COMPLEX SUBUNIT ALPHA-2, AP-2 COMPLEX SUBUNIT BETA, AP-2 COMPLEX SUBUNIT MU, ... | | Authors: | Kelly, B.T, Graham, S.C, Liska, N, Dannhauser, P.N, Hoening, S, Ungewickell, E.J, Owen, D.J. | | Deposit date: | 2014-06-23 | | Release date: | 2014-07-30 | | Last modified: | 2024-01-10 | | Method: | X-RAY DIFFRACTION (2.79 Å) | | Cite: | Clathrin Adaptors. Ap2 Controls Clathrin Polymerization with a Membrane-Activated Switch.
Science, 345, 2014
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5M61
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