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6ABX	Crystal structure of citrate synthase (Msed_1522) from Metallosphaera sedula in complex with citrate Descriptor: CITRATE ANION, Citrate synthase, GLYCEROL Authors: Lee, S.-H, Son, H.-F, Kim, K.-J. Deposit date: 2018-07-24 Release date: 2019-03-13 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Structural insights into the inhibition properties of archaeon citrate synthase from Metallosphaera sedula. PLoS ONE, 14, 2019
1O7X	Citrate synthase from Sulfolobus solfataricus Descriptor: CITRATE SYNTHASE Authors: Bell, G.S, Russell, R.J.M, Connaris, H, Hough, D.W, Danson, M.J, Taylor, G.L. Deposit date: 2002-11-19 Release date: 2002-12-12 Last modified: 2024-05-08 Method: X-RAY DIFFRACTION (2.7 Å) Cite: Stepwise Adaptations of Citrate Synthase to Survival at Life'S Extremes. From Psychrophile to Hyperthermophile. Eur.J.Biochem., 269, 2002
9XAU	Glyoxysomal Citrate Synthase 3 from Arabidopsis thaliana in complex with OAA Descriptor: Citrate synthase 3, peroxisomal, GLYCEROL, ... Authors: Nishio, K, Takagi, K, Mizushima, T. Deposit date: 2025-10-23 Release date: 2026-02-04 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.95 Å) Cite: Crystal structure of glyoxysomal citrate synthase 3 from Arabidopsis thaliana reveals a novel oligomeric state. J.Struct.Biol., 218, 2026
1AJ8	CITRATE SYNTHASE FROM PYROCOCCUS FURIOSUS Descriptor: CITRATE SYNTHASE, CITRIC ACID, COENZYME A Authors: Russell, R.J.M, Ferguson, J.M.C, Hough, D.W, Danson, M.J, Taylor, G.L. Deposit date: 1997-05-16 Release date: 1997-11-19 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (1.9 Å) Cite: The crystal structure of citrate synthase from the hyperthermophilic archaeon pyrococcus furiosus at 1.9 A resolution,. Biochemistry, 36, 1997
6HXM	Structure of the citryl-CoA lyase core module of human ATP citrate lyase in complex with citrate and CoASH in space group C2221 Descriptor: ATP-citrate synthase, CITRATE ANION, COENZYME A Authors: Verstraete, K, Verschueren, K. Deposit date: 2018-10-17 Release date: 2019-04-10 Last modified: 2024-05-01 Method: X-RAY DIFFRACTION (1.3 Å) Cite: Structure of ATP citrate lyase and the origin of citrate synthase in the Krebs cycle. Nature, 568, 2019
3IVU	Homocitrate Synthase Lys4 bound to 2-OG Descriptor: 2-OXOGLUTARIC ACID, COBALT (II) ION, Homocitrate synthase, ... Authors: Bulfer, S.L, Scott, E.M, Couture, J.-F, Pillus, L, Trievel, R.C. Deposit date: 2009-09-01 Release date: 2009-09-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.72 Å) Cite: Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis. J.Biol.Chem., 284, 2009
3IVT	Homocitrate Synthase Lys4 bound to 2-OG Descriptor: 2-OXOGLUTARIC ACID, Homocitrate synthase, mitochondrial, ... Authors: Bulfer, S.L, Scott, E.M, Couture, J.-F, Pillus, L, Trievel, R.C. Deposit date: 2009-09-01 Release date: 2009-09-22 Last modified: 2024-04-03 Method: X-RAY DIFFRACTION (2.67 Å) Cite: Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis. J.Biol.Chem., 284, 2009
3IVS	Homocitrate Synthase Lys4 Descriptor: COBALT (II) ION, Homocitrate synthase, mitochondrial, ... Authors: Bulfer, S.L, Scott, E.M, Couture, J.-F, Pillus, L, Trievel, R.C. Deposit date: 2009-09-01 Release date: 2009-09-22 Last modified: 2024-10-30 Method: X-RAY DIFFRACTION (2.24 Å) Cite: Crystal structure and functional analysis of homocitrate synthase, an essential enzyme in lysine biosynthesis. J.Biol.Chem., 284, 2009
3MI3	Homocitrate Synthase Lys4 bound to Lysine Descriptor: Homocitrate synthase, mitochondrial, LYSINE, ... Authors: Bulfer, S.L, Scott, E.M, Pillus, L, Trievel, R.C. Deposit date: 2010-04-09 Release date: 2010-04-28 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.38 Å) Cite: Structural Basis for L-lysine Feedback Inhibition of Homocitrate Synthase J.Biol.Chem., 285, 2010
5CSC	STRUCTURE OF AN OPEN FORM OF CHICKEN HEART CITRATE SYNTHASE AT 2.8 ANGSTROMS RESOLUTION Descriptor: CITRATE SYNTHASE Authors: Liao, D.-I, Karpusas, M, Remington, S.J. Deposit date: 1990-05-07 Release date: 1991-04-15 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Crystal structure of an open conformation of citrate synthase from chicken heart at 2.8-A resolution Biochemistry, 30, 1991
9XDG	Glyoxysomal Citrate Synthase 3 from Arabidopsis thaliana in complex with OAA and MNB Descriptor: 1,2-ETHANEDIOL, 5-MERCAPTO-2-NITRO-BENZOIC ACID, Citrate synthase 3, ... Authors: Nishio, K, Takagi, K, Mizushima, T. Deposit date: 2025-10-27 Release date: 2026-02-04 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (2.294 Å) Cite: Crystal structure of glyoxysomal citrate synthase 3 from Arabidopsis thaliana reveals a novel oligomeric state. J.Struct.Biol., 218, 2026
9X0I	Glyoxysomal Citrate Synthase 3 from Arabidopsis thaliana in complex with OAA and CoA Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, COENZYME A, ... Authors: Nishio, K, Takagi, K, Mizushima, T. Deposit date: 2025-09-30 Release date: 2026-02-04 Last modified: 2026-02-18 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Crystal structure of glyoxysomal citrate synthase 3 from Arabidopsis thaliana reveals a novel oligomeric state. J.Struct.Biol., 218, 2026
7E8N	Crystal structure of Type II citrate synthase (HyCS) from Hymenobacter sp. PAMC 26554 Descriptor: CITRIC ACID, Citrate synthase Authors: Park, S.-H, Lee, C.W, Bae, D.-W, Lee, J.H. Deposit date: 2021-03-02 Release date: 2022-01-12 Last modified: 2025-09-17 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Structural basis of the cooperative activation of type II citrate synthase (HyCS) from Hymenobacter sp. PAMC 26554. Int.J.Biol.Macromol., 183, 2021
5UZP	Crystal structure of citrate synthase mutant A348G from homo sapiens Descriptor: Citrate synthase, mitochondrial, OXALOACETATE ION Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-02-27 Release date: 2018-03-07 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.29 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
5UQO	Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus Descriptor: 2-methylcitrate synthase, mitochondrial Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-02-08 Release date: 2018-02-14 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
5UQU	Crystal structure of mutant 2-methylcitrate synthase (mcsAG352A) from Aspergillus fumigatus Descriptor: 2-methylcitrate synthase, mitochondrial, COENZYME A, ... Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-02-08 Release date: 2018-02-14 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.7 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
5UQQ	Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus Descriptor: 2-methylcitrate synthase, mitochondrial, S,R MESO-TARTARIC ACID Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-02-08 Release date: 2018-02-14 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.3 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
5UQR	Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus Descriptor: 2-methylcitrate synthase, mitochondrial, OXALOACETATE ION, ... Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-02-08 Release date: 2018-03-14 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
1A59	COLD-ACTIVE CITRATE SYNTHASE Descriptor: CITRATE SYNTHASE, CITRIC ACID, COENZYME A Authors: Russell, R.J.M, Gerike, U, Danson, M.J, Hough, D.W, Taylor, G.L. Deposit date: 1998-02-20 Release date: 1999-03-30 Last modified: 2024-02-07 Method: X-RAY DIFFRACTION (2.09 Å) Cite: Structural adaptations of the cold-active citrate synthase from an Antarctic bacterium. Structure, 6, 1998
6BON	Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus with oxaloacetate and coenzyme-A. Descriptor: 2-methylcitrate synthase, mitochondrial, COENZYME A, ... Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-11-20 Release date: 2018-11-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.35 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
6BOP	Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus Descriptor: 2-methylcitrate synthase, mitochondrial Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-11-20 Release date: 2018-11-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.71 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
6BOO	Crystal structure of 2-methylcitrate synthase from Aspergillus fumigatus with oxaloacetate and coenzyme-A. Descriptor: 2-methylcitrate synthase, mitochondrial, COENZYME A, ... Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-11-20 Release date: 2018-11-28 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.6 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
6BOL	Crystal structure of mutant 2-methylcitrate synthase mcsAG419A from Aspergillus fumigatus. Descriptor: 2-methylcitrate synthase, mitochondrial, CHLORIDE ION, ... Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-11-20 Release date: 2018-11-28 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
5UZQ	Crystal structure of citrate synthase from homo sapiens Descriptor: Citrate synthase Authors: Schlachter, C, Chruszcz, M. Deposit date: 2017-02-27 Release date: 2018-03-07 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (2.16 Å) Cite: Comparative studies of Aspergillus fumigatus 2-methylcitrate synthase and human citrate synthase. Biol.Chem., 400, 2019
6CTS	PROPOSED MECHANISM FOR THE CONDENSATION REACTION OF CITRATE SYNTHASE. 1.9-ANGSTROMS STRUCTURE OF THE TERNARY COMPLEX WITH OXALOACETATE AND CARBOXYMETHYL COENZYME A Descriptor: CITRATE SYNTHASE, CITRYL-THIOETHER-COENZYME *A Authors: Karpusas, M, Branchaud, B, Remington, S.J. Deposit date: 1989-11-16 Release date: 1990-10-15 Last modified: 2024-03-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: Proposed mechanism for the condensation reaction of citrate synthase: 1.9-A structure of the ternary complex with oxaloacetate and carboxymethyl coenzyme A. Biochemistry, 29, 1990

 

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