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6AVU
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BU of 6avu by Molmil
Human alpha-V beta-3 Integrin (open conformation) in complex with the therapeutic antibody LM609
Descriptor: Fab LM609 heavy chain, Fab LM609 light chain, Integrin alpha-V, ...
Authors:Borst, A.J, James, Z.N, Zagotta, W.N, Ginsberg, M, Rey, F.A, DiMaio, F, Backovic, M, Veesler, D.
Deposit date:2017-09-04
Release date:2017-11-01
Last modified:2024-03-13
Method:ELECTRON MICROSCOPY (35 Å)
Cite:The Therapeutic Antibody LM609 Selectively Inhibits Ligand Binding to Human alpha V beta 3 Integrin via Steric Hindrance.
Structure, 25, 2017
3HO5
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BU of 3ho5 by Molmil
Crystal structure of Hedgehog-interacting protein (HHIP) and Sonic hedgehog (SHH) complex
Descriptor: CALCIUM ION, Hedgehog-interacting protein, Sonic hedgehog protein, ...
Authors:Hymowitz, S.G, Bosanac, I.
Deposit date:2009-06-01
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.01 Å)
Cite:The structure of SHH in complex with HHIP reveals a recognition role for the Shh pseudo active site in signaling.
Nat.Struct.Mol.Biol., 16, 2009
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219869

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