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7RP0
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BU of 7rp0 by Molmil
Structural Snapshots of Intermediates in the Gating of a K+ Channel
Descriptor: DIACYL GLYCEROL, KcsA Fab chain A, KcsA Fab chain B, ...
Authors:Reddi, R, Matulef, K, Riederer, E.A, Valiyaveetil, F.I.
Deposit date:2021-08-02
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.48 Å)
Cite:Structures of Gating Intermediates in a K + channell.
J.Mol.Biol., 433, 2021
7SK1
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BU of 7sk1 by Molmil
TWIK1 in MSP1E3D1 Lipid Nanodisc at pH 5.5
Descriptor: N-OCTANE, POTASSIUM ION, Potassium channel subfamily K member 1, ...
Authors:Turney, T.S, Brohawn, S.G.
Deposit date:2021-10-19
Release date:2021-11-24
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (3.43 Å)
Cite:Structural Basis for pH-gating of the K + channel TWIK1 at the selectivity filter.
Nat Commun, 13, 2022
7SK0
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BU of 7sk0 by Molmil
TWIK1 in MSP1D1 lipid nanodisc at pH 7.4
Descriptor: N-OCTANE, POTASSIUM ION, Potassium channel subfamily K member 1
Authors:Turney, T.S, Brohawn, S.G.
Deposit date:2021-10-19
Release date:2021-11-24
Last modified:2022-06-22
Method:ELECTRON MICROSCOPY (3.33 Å)
Cite:Structural Basis for pH-gating of the K + channel TWIK1 at the selectivity filter.
Nat Commun, 13, 2022
7SQW
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BU of 7sqw by Molmil
Structure of the KcsA-W67F mutant with the activation gate in the closed conformation
Descriptor: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Antibody Fragment, KcsA potassium channel, ...
Authors:Cuello, L.G, Labro, A.J.
Deposit date:2021-11-07
Release date:2022-10-12
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.21 Å)
Cite:The nonconducting W434F mutant adopts upon membrane depolarization an inactivated-like state that differs from wild-type Shaker-IR potassium channels.
Sci Adv, 8, 2022
4ZBM
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BU of 4zbm by Molmil
Crystal structure of Drosophila cyclic nucleotide gated channel pore mimicking NaK mutant
Descriptor: BARIUM ION, POTASSIUM ION, Potassium channel protein
Authors:Lam, Y, Zeng, W, Derebe, M.G, Jiang, Y.
Deposit date:2015-04-14
Release date:2015-07-29
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Structural implications of weak Ca2+ block in Drosophila cyclic nucleotide-gated channels.
J.Gen.Physiol., 146, 2015
3OGC
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BU of 3ogc by Molmil
KcsA E71A variant in presence of Na+
Descriptor: SODIUM ION, Voltage-gated potassium channel, antibody Fab fragment heavy chain, ...
Authors:McCoy, J.G, Nimigean, C.M.
Deposit date:2010-08-16
Release date:2011-03-16
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Mechanism for selectivity-inactivation coupling in KcsA potassium channels.
Proc.Natl.Acad.Sci.USA, 108, 2011
8A7X
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BU of 8a7x by Molmil
NaK C-DI F92A mutant soaked in Cs+
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CESIUM ION, POTASSIUM ION, ...
Authors:Minniberger, S, Plested, A.J.R.
Deposit date:2022-06-21
Release date:2023-02-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Asymmetry and Ion Selectivity Properties of Bacterial Channel NaK Mutants Derived from Ionotropic Glutamate Receptors.
J.Mol.Biol., 435, 2023
8A35
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BU of 8a35 by Molmil
NaK C-DI mutant with Rb+ and Na+
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, Potassium channel protein, RUBIDIUM ION, ...
Authors:Minniberger, S, Plested, A.J.R.
Deposit date:2022-06-07
Release date:2023-02-01
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.05 Å)
Cite:Asymmetry and Ion Selectivity Properties of Bacterial Channel NaK Mutants Derived from Ionotropic Glutamate Receptors.
J.Mol.Biol., 435, 2023
3OR7
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BU of 3or7 by Molmil
On the structural basis of modal gating behavior in K+channels - E71I
Descriptor: POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ...
Authors:Chakrapani, S, Cordero-Morales, J.F, Jogini, V, Pan, A.C, Cortes, D.M, Roux, B, Perozo, E.
Deposit date:2010-09-06
Release date:2011-01-05
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:On the structural basis of modal gating behavior in K(+) channels.
Nat.Struct.Mol.Biol., 18, 2011
3OUS
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BU of 3ous by Molmil
MthK channel pore T59A mutant
Descriptor: Calcium-gated potassium channel mthK, POTASSIUM ION
Authors:Derebe, M.G, Sauer, D.B, Zeng, W, Alam, A, Shi, N, Jiang, Y.
Deposit date:2010-09-15
Release date:2011-01-12
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Tuning the ion selectivity of tetrameric cation channels by changing the number of ion binding sites.
Proc.Natl.Acad.Sci.USA, 108, 2011
3OR6
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BU of 3or6 by Molmil
On the structural basis of modal gating behavior in K+channels - E71Q
Descriptor: POTASSIUM ION, Voltage-gated potassium channel, antibody fab fragment heavy chain, ...
Authors:Chakrapani, S, Cordero-Morales, J.F, Jogini, V, Perozo, E.
Deposit date:2010-09-06
Release date:2011-01-05
Last modified:2018-08-29
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:On the structural basis of modal gating behavior in K(+) channels.
Nat.Struct.Mol.Biol., 18, 2011
8AYP
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BU of 8ayp by Molmil
NaK C-DI mutant with Rb+ and Ba2+
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, BARIUM ION, Potassium channel protein, ...
Authors:Minniberger, S, Plested, A.J.R.
Deposit date:2022-09-02
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Mechanism of Calcium Permeation in a Glutamate Receptor Ion Channel.
J.Chem.Inf.Model., 63, 2023
7LJ5
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BU of 7lj5 by Molmil
Human TRAAK K+ channel FHIEG mutant A198E in a K+ bound conductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Rietmeijer, R.A, Brohawn, S.G.
Deposit date:2021-01-28
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.26 Å)
Cite:Physical basis for distinct basal and mechanically gated activity of the human K + channel TRAAK.
Neuron, 109, 2021
7LJB
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BU of 7ljb by Molmil
Human TRAAK K+ channel mutant G158D in a K+ bound conductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Rietmeijer, R.A, Brohawn, S.G.
Deposit date:2021-01-28
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.97 Å)
Cite:Physical basis for distinct basal and mechanically gated activity of the human K + channel TRAAK.
Neuron, 109, 2021
7LJA
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BU of 7lja by Molmil
Human TRAAK K+ channel FHEIG mutant A198E in a Tl+ bound conductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Rietmeijer, R.A, Brohawn, S.G.
Deposit date:2021-01-28
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.77 Å)
Cite:Physical basis for distinct basal and mechanically gated activity of the human K + channel TRAAK.
Neuron, 109, 2021
7LJ4
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BU of 7lj4 by Molmil
Human TRAAK K+ channel FHEIG mutant A270P in a K+ bound conductive conformation
Descriptor: ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT HEAVY CHAIN, ANTI-TRAAK ANTIBODY 13E9 FAB FRAGMENT LIGHT CHAIN, CALCIUM ION, ...
Authors:Rietmeijer, R.A, Brohawn, S.G.
Deposit date:2021-01-28
Release date:2021-06-30
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.782 Å)
Cite:Physical basis for distinct basal and mechanically gated activity of the human K + channel TRAAK.
Neuron, 109, 2021
8AYQ
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BU of 8ayq by Molmil
NaK C-DI mutant with Rb+ and Ca2+
Descriptor: (4S)-2-METHYL-2,4-PENTANEDIOL, CALCIUM ION, CHLORIDE ION, ...
Authors:Minniberger, S, Plested, A.J.R.
Deposit date:2022-09-02
Release date:2023-02-22
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Mechanism of Calcium Permeation in a Glutamate Receptor Ion Channel.
J.Chem.Inf.Model., 63, 2023
5A6G
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BU of 5a6g by Molmil
Cryo-EM structure of the Slo2.2 Na-activated K channel
Descriptor: PORE DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1, S1-S4 DOMAIN OF POTASSIUM CHANNEL SUBFAMILY T MEMBER 1
Authors:Hite, R.K, Yuan, P, Li, Z, Hsuing, Y, Walz, T, MacKinnon, R.
Deposit date:2015-06-25
Release date:2015-10-14
Last modified:2024-05-08
Method:ELECTRON MICROSCOPY (5.2 Å)
Cite:Cryo-Electron Microscopy Structure of the Slo2.2 Na1-Activated K1 Channel
Nature, 527, 2015
3PJS
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BU of 3pjs by Molmil
Mechanism of Activation Gating in the Full-Length KcsA K+ Channel
Descriptor: FAB heavy chain, FAB light chain, Voltage-gated potassium channel
Authors:Uysal, S, Cuello, L.G, Kossiakoff, A, Perozo, E.
Deposit date:2010-11-10
Release date:2011-07-06
Last modified:2011-08-03
Method:X-RAY DIFFRACTION (3.8 Å)
Cite:Mechanism of activation gating in the full-length KcsA K+ channel.
Proc.Natl.Acad.Sci.USA, 108, 2011
7M2I
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BU of 7m2i by Molmil
Structural Snapshots of Intermediates in the Gating of a K+ Channel
Descriptor: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, Monoclonal antibody (IgG) against KcsA, Fab heavy chain, ...
Authors:Reddi, R, Valiyaveetil, F.I.
Deposit date:2021-03-16
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.695 Å)
Cite:Structures of Gating Intermediates in a K + channell.
J.Mol.Biol., 433, 2021
7M2H
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BU of 7m2h by Molmil
Structural Snapshots of Intermediates in the Gating of a K+ Channel
Descriptor: DIACYL GLYCEROL, Fab heavy chain, Fab light chain, ...
Authors:Reddi, R, Valiyaveetil, F.I.
Deposit date:2021-03-16
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.642 Å)
Cite:Structures of Gating Intermediates in a K + channell.
J.Mol.Biol., 433, 2021
7M2J
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BU of 7m2j by Molmil
Structural Snapshots of Intermediates in the Gating of a K+ Channel
Descriptor: Monoclonal antibody (IgG) against KcsA, Fab heavy chain, Fab light chain, ...
Authors:Reddi, R, Valiyaveetil, F.I.
Deposit date:2021-03-16
Release date:2021-10-27
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.201 Å)
Cite:Structures of Gating Intermediates in a K + channell.
J.Mol.Biol., 433, 2021
7MDJ
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BU of 7mdj by Molmil
The structure of KcsA in complex with a synthetic Fab
Descriptor: Fab heavy chain, Fab light chain, POTASSIUM ION, ...
Authors:Rohaim, A, Slezak, T, Blackowicz, L, Kossiakoff, A, Roux, B.
Deposit date:2021-04-05
Release date:2022-02-16
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.75 Å)
Cite:Engineering of a synthetic antibody fragment for structural and functional studies of K+ channels.
J.Gen.Physiol., 154, 2022
7MHX
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BU of 7mhx by Molmil
KcsA E71V closed gate with Ba2+
Descriptor: BARIUM ION, DIACYL GLYCEROL, Fab heavy chain, ...
Authors:Rohaim, A, Li, J, Weingarth, M, Roux, B.
Deposit date:2021-04-15
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.85 Å)
Cite:A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V.
Nat Commun, 13, 2022
7MJT
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BU of 7mjt by Molmil
KcsA open gate E71V mutant with Barium
Descriptor: BARIUM ION, Fab heavy chain, Fab light chain, ...
Authors:Rohaim, A, Li, J, Weingarth, M, Roux, B.
Deposit date:2021-04-20
Release date:2022-03-23
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:A distinct mechanism of C-type inactivation in the Kv-like KcsA mutant E71V.
Nat Commun, 13, 2022

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