PDB: 303 件ウェブページステータス検索Chemie searchBIRD

---

4XDK	Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in complex with norfluoxetine 分子名称: (3R)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, (3S)-3-phenyl-3-[4-(trifluoromethyl)phenoxy]propan-1-amine, 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, ... 著者 Pike, A.C.W, Dong, Y.Y, Mackenzie, A, Mukhopadhyay, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Carpenter, E.P, Structural Genomics Consortium (SGC) 登録日 2014-12-19 公開日 2015-03-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.6 Å) 主引用文献 K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac. Science, 347, 2015
4XDL	Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in complex with a brominated fluoxetine derivative. 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, 3-[2-bromanyl-4-(trifluoromethyl)phenoxy]-N-methyl-3-phenyl-propan-1-amine, CADMIUM ION, ... 著者 Mackenzie, A, Pike, A.C.W, Dong, Y.Y, Mukhopadhyay, S, Ruda, G.F, Brennan, P.E, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Carpenter, E.P, Structural Genomics Consortium (SGC) 登録日 2014-12-19 公開日 2015-03-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.5 Å) 主引用文献 K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac. Science, 347, 2015
4XDJ	Crystal structure of human two pore domain potassium ion channel TREK2 (K2P10.1) in an alternate conformation (FORM 2) 分子名称: 1,2-DIACYL-SN-GLYCERO-3-PHOSPHOCHOLINE, POTASSIUM CHANNEL SUBFAMILY K MEMBER 10, POTASSIUM ION, ... 著者 Pike, A.C.W, Dong, Y.Y, Mackenzie, A, Mukhopadhyay, S, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Burgess-Brown, N.A, Carpenter, E.P, Structural Genomics Consortium (SGC) 登録日 2014-12-19 公開日 2015-03-18 最終更新日 2024-01-10 実験手法 X-RAY DIFFRACTION (3.8 Å) 主引用文献 K2P channel gating mechanisms revealed by structures of TREK-2 and a complex with Prozac. Science, 347, 2015
4LBE	Structure of KcsA with R122A mutation 分子名称: DIACYL GLYCEROL, Fab heavy chain, Fab light chain, ... 著者 Nimigean, C.M, Posson, D.J, McCoy, J.M. 登録日 2013-06-20 公開日 2013-10-30 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.751 Å) 主引用文献 Molecular interactions involved in proton-dependent gating in KcsA potassium channels. J.Gen.Physiol., 142, 2013
4LCU	Structure of KcsA with E118A mutation 分子名称: DIACYL GLYCEROL, Fab heavy chain, Fab light chain, ... 著者 Nimigean, C.M, Posson, D.J, McCoy, J.M. 登録日 2013-06-23 公開日 2013-10-30 最終更新日 2017-11-15 実験手法 X-RAY DIFFRACTION (2.752 Å) 主引用文献 Molecular interactions involved in proton-dependent gating in KcsA potassium channels. J.Gen.Physiol., 142, 2013
1ZWI	Structure of mutant KcsA potassium channel 分子名称: DIACYL GLYCEROL, NONAN-1-OL, POTASSIUM ION, ... 著者 Cordero-Morales, J.F, Cuello, L.G, Zhao, Y, Jogini, V, Cortes, D.M, Roux, B, Perozo, E. 登録日 2005-06-03 公開日 2006-03-07 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular determinants of gating at the potassium-channel selectivity filter. Nat.Struct.Mol.Biol., 13, 2006
2AHY	Na+ complex of the NaK Channel 分子名称: CALCIUM ION, Potassium channel protein, SODIUM ION 著者 Shi, N, Ye, S, Alam, A, Chen, L, Jiang, Y. 登録日 2005-07-28 公開日 2006-02-07 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Atomic structure of a Na+- and K+-conducting channel. Nature, 440, 2006
2AHZ	K+ complex of the NaK Channel 分子名称: CALCIUM ION, POTASSIUM ION, Potassium channel protein 著者 Shi, N, Ye, S, Alam, A, Chen, L, Jiang, Y. 登録日 2005-07-28 公開日 2006-02-07 最終更新日 2023-08-23 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Atomic structure of a Na+- and K+-conducting channel. Nature, 440, 2006
2ATK	Structure of a mutant KcsA K+ channel 分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, NONAN-1-OL, ... 著者 Cordero-Morales, J.F, Cuello, L.G, Zhao, Y, Jogini, V, Chakrapani, S, Roux, B, Perozo, E. 登録日 2005-08-25 公開日 2006-03-07 最終更新日 2021-11-10 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Molecular determinants of gating at the potassium-channel selectivity filter. Nat.Struct.Mol.Biol., 13, 2006
2HVJ	Crystal structure of KcsA-Fab-TBA complex in low K+ 分子名称: (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, NONAN-1-OL, POTASSIUM ION, ... 著者 Zhou, Y. 登録日 2006-07-28 公開日 2007-02-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.75 Å) 主引用文献 Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel. J.Mol.Biol., 366, 2007
2HVK	crystal structure of the KcsA-Fab-TBA complex in high K+ 分子名称: (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, Antibody Fab heavy chain, Antibody Fab light chain, ... 著者 Zhou, Y. 登録日 2006-07-28 公開日 2007-02-20 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel. J.Mol.Biol., 366, 2007
2IH3	Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation 分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB Heavy Chain, FAB Light Chain, ... 著者 Valiyaveetil, F.I, Leonetti, M, Muir, T.W, MacKinnon, R. 登録日 2006-09-25 公開日 2006-11-21 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (1.72 Å) 主引用文献 Ion Selectivity in a Semisynthetic K+ Channel Locked in the Conductive Conformation. Science, 314, 2006
2ITD	Potassium Channel KcsA-Fab complex in Barium Chloride 分子名称: BARIUM ION, Voltage-gated potassium channel, antibody Fab fragment heavy chain, ... 著者 Lockless, S.W, Zhou, M, MacKinnon, R. 登録日 2006-10-19 公開日 2007-05-15 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.7 Å) 主引用文献 Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Plos Biol., 5, 2007
2ITC	Potassium Channel KcsA-Fab complex in Sodium Chloride 分子名称: Antibody Fab fragment heavy chain, Antibody Fab fragment light chain, SODIUM ION, ... 著者 Lockless, S.W, Zhou, M, MacKinnon, R. 登録日 2006-10-19 公開日 2007-05-15 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (3.2 Å) 主引用文献 Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Plos Biol., 5, 2007
2BOB	Potassium channel KcsA-Fab complex in thallium with tetrabutylammonium (TBA) 分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... 著者 Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A. 登録日 2005-04-09 公開日 2005-04-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.76 Å) 主引用文献 Structural Basis of Tea Blockade in a Model Potassium Channel Nat.Struct.Mol.Biol., 12, 2005
2BOC	Potassium channel KcsA-Fab complex in thallium with tetraethylarsonium (TEAs) 分子名称: ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, COBALT (II) ION, ... 著者 Lenaeus, M.J, Vamvouka, M, Focia, P.J, Gross, A. 登録日 2005-04-09 公開日 2005-04-27 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.01 Å) 主引用文献 Structural Basis of Tea Blockade in a Model Potassium Channel Nat.Struct.Mol.Biol., 12, 2005
2IH1	Ion selectivity in a semi-synthetic K+ channel locked in the conductive conformation 分子名称: (1S)-2-HYDROXY-1-[(NONANOYLOXY)METHYL]ETHYL MYRISTATE, FAB Heavy Chain, FAB Light Chain, ... 著者 Valiyaveetil, F.I, Leonetti, M, Muir, T.W, MacKinnon, R. 登録日 2006-09-25 公開日 2006-11-21 最終更新日 2021-10-20 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Ion Selectivity in a Semisynthetic K+ Channel Locked in the Conductive Conformation. Science, 314, 2006
2JK5	Potassium Channel KcsA in complex with Tetrabutylammonium in high K 分子名称: (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, ANTIBODY FAB FRAGMENT HEAVY CHAIN, ANTIBODY FAB FRAGMENT LIGHT CHAIN, ... 著者 Lenaeus, M.J, Focia, P.J, Wagner, T, Gross, A. 登録日 2008-08-15 公開日 2009-11-17 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Structures of Kcsa in Complex with Symmetrical Quaternary Ammonium Compounds Reveal a Hydrophobic Binding Site. Biochemistry, 53, 2014
2DWD	crystal structure of KcsA-FAB-TBA complex in Tl+ 分子名称: (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, ANTIBODY FAB HEAVY CHAIN, ANTIBODY FAB LIGHT CHAIN, ... 著者 Yohannan, S, Zhou, Y. 登録日 2006-08-10 公開日 2007-02-20 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.6 Å) 主引用文献 Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel J.Mol.Biol., 366, 2007
2DWE	Crystal structure of KcsA-FAB-TBA complex in Rb+ 分子名称: (2S)-3-HYDROXY-2-(NONANOYLOXY)PROPYL LAURATE, ANTIBODY FAB HEAVY CHAIN, ANTIBODY FAB LIGHT CHAIN, ... 著者 Yohannan, S, Zhou, Y. 登録日 2006-08-10 公開日 2007-02-20 最終更新日 2023-10-25 実験手法 X-RAY DIFFRACTION (2.5 Å) 主引用文献 Crystallographic Study of the Tetrabutylammonium Block to the KcsA K(+) Channel J.Mol.Biol., 366, 2007
2NLJ	Potassium Channel KcsA(M96V)-Fab complex in KCl 分子名称: DIACYL GLYCEROL, POTASSIUM ION, Voltage-gated potassium channel, ... 著者 Lockless, S.W, Zhou, M, MacKinnon, R. 登録日 2006-10-20 公開日 2007-05-15 最終更新日 2023-12-27 実験手法 X-RAY DIFFRACTION (2.52 Å) 主引用文献 Structural and Thermodynamic Properties of Selective Ion Binding in a K(+) Channel. Plos Biol., 5, 2007
2HFE	Rb+ complex of a K channel with an amide to ester substitution in the selectivity filter 分子名称: (2S)-2-(BUTYRYLOXY)-3-HYDROXYPROPYL NONANOATE, FAB Heavy Chain, FAB Light Chain, ... 著者 Valiyaveetil, F.I, MacKinnon, R, Muir, T.W. 登録日 2006-06-23 公開日 2006-09-12 最終更新日 2024-03-27 実験手法 X-RAY DIFFRACTION (2.25 Å) 主引用文献 Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel. J.Am.Chem.Soc., 128, 2006
2HJF	Potassium channel kcsa-fab complex with tetrabutylammonium (TBA) 分子名称: Antibody fragment Heavy chain, Antibody fragment Light chain, POTASSIUM ION, ... 著者 Faraldo-Gomez, J.D, Kutluay, E, Jogini, V, Zhao, Y, Heginbotham, L, Roux, B. 登録日 2006-06-30 公開日 2006-12-05 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.9 Å) 主引用文献 Mechanism of Intracellular Block of the KcsA K(+) Channel by Tetrabutylammonium: Insights from X-ray Crystallography, Electrophysiology and Replica-exchange Molecular Dynamics Simulations. J.Mol.Biol., 365, 2007
8K1V	Human TWIK-related acid-sensitive potassium channel TASK3 at pH 7.4, 5 mM KCl and 135 mM NaCl 分子名称: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9 著者 Chen, S, Lin, H. 登録日 2023-07-11 公開日 2024-04-17 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.48 Å) 主引用文献 C-type inactivation and proton modulation mechanisms of the TASK3 channel. Proc.Natl.Acad.Sci.USA, 121, 2024
8K1Q	Human TWIK-related acid-sensitive potassium channel TASK3 at pH 6.0, 5 mM KCl and 135 mM NaCl 分子名称: CHOLESTEROL HEMISUCCINATE, POTASSIUM ION, Potassium channel subfamily K member 9 著者 Chen, S, Lin, H. 登録日 2023-07-11 公開日 2024-04-17 最終更新日 2024-05-01 実験手法 ELECTRON MICROSCOPY (3.68 Å) 主引用文献 C-type inactivation and proton modulation mechanisms of the TASK3 channel. Proc.Natl.Acad.Sci.USA, 121, 2024

<12345678910111213>