PDB: 83 resultsInfo pagesStatus searchChemie searchBIRD

---

2NYM	Crystal Structure of Protein Phosphatase 2A (PP2A) with C-terminus truncated catalytic subunit Descriptor: MANGANESE (II) ION, Protein phosphatase 2, Serine/threonine-protein phosphatase 2A 56 kDa regulatory subunit gamma isoform, ... Authors: Chen, Y, Xing, Y, Xu, Y, Chao, Y, Lin, Z, Jeffrey, P.D, Shi, Y. Deposit date: 2006-11-21 Release date: 2006-12-12 Last modified: 2023-11-15 Method: X-RAY DIFFRACTION (3.6 Å) Cite: Structure of the Protein Phosphatase 2A Holoenzyme. Cell(Cambridge,Mass.), 127, 2006
2PF4	Crystal structure of the full-length simian virus 40 small t antigen complexed with the protein phosphatase 2A Aalpha subunit Descriptor: Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A alpha isoform, Small T antigen, ZINC ION Authors: Cho, U, Morrone, S, Xu, W. Deposit date: 2007-04-03 Release date: 2007-08-07 Last modified: 2023-08-30 Method: X-RAY DIFFRACTION (3.1 Å) Cite: Structural basis of PP2A inhibition by small t antigen. Plos Biol., 5, 2007
7PEB	cryo-EM structure of DEPTOR bound to human mTOR complex 1, focussed on one protomer Descriptor: DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, Regulatory-associated protein of mTOR, ... Authors: Waelchli, M, Maier, T. Deposit date: 2021-08-09 Release date: 2021-09-08 Last modified: 2021-09-29 Method: ELECTRON MICROSCOPY (3.67 Å) Cite: Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7OWG	human DEPTOR in a complex with mutant human mTORC1 A1459P Descriptor: DEP domain-containing mTOR-interacting protein, Regulatory-associated protein of mTOR, Serine/threonine-protein kinase mTOR, ... Authors: Heimhalt, M, Berndt, A, Wagstaff, J, Anandapadamanaban, M, Perisic, O, Maslen, S, McLaughlin, S, Yu, W.-H, Masson, G.R, Boland, A, Ni, X, Yamashita, K, Murshudov, G.N, Skehel, M, Freund, S.M, Williams, R.L. Deposit date: 2021-06-18 Release date: 2021-09-08 Last modified: 2022-02-23 Method: ELECTRON MICROSCOPY (4.7 Å) Cite: Bipartite binding and partial inhibition links DEPTOR and mTOR in a mutually antagonistic embrace. Elife, 10, 2021
7PEA	cryo-EM structure of DEPTOR bound to human mTOR complex 1, overall refinement Descriptor: DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, Regulatory-associated protein of mTOR, ... Authors: Waelchli, M, Maier, T. Deposit date: 2021-08-09 Release date: 2021-09-08 Last modified: 2021-09-29 Method: ELECTRON MICROSCOPY (4.07 Å) Cite: Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PEC	cryo-EM structure of DEPTOR bound to human mTOR complex 1, DEPt-bound subset local refinement Descriptor: DEP domain-containing mTOR-interacting protein, INOSITOL HEXAKISPHOSPHATE, Regulatory-associated protein of mTOR, ... Authors: Waelchli, M, Maier, T. Deposit date: 2021-08-09 Release date: 2021-09-08 Last modified: 2021-09-29 Method: ELECTRON MICROSCOPY (4.24 Å) Cite: Regulation of human mTOR complexes by DEPTOR. Elife, 10, 2021
7PKS	Structural basis of Integrator-mediated transcription regulation Descriptor: DNA Template, DNA-directed RNA polymerase II subunit E, DNA-directed RNA polymerase II subunit F, ... Authors: Fianu, I, Chen, Y, Dienemann, C, Cramer, P. Deposit date: 2021-08-26 Release date: 2021-12-08 Method: ELECTRON MICROSCOPY (3.6 Å) Cite: Structural basis of Integrator-mediated transcription regulation. Science, 374, 2021
7PQH	Cryo-EM structure of Saccharomyces cerevisiae TOROID (TORC1 Organized in Inhibited Domains). Descriptor: Serine/threonine-protein kinase TOR2, Target of rapamycin complex 1 subunit KOG1,Target of rapamycin complex 1 subunit Kog1, Target of rapamycin complex subunit LST8 Authors: Felix, J, Prouteau, M, Bourgoint, C, Bonadei, L, Desfosses, A, Gabus, C, Sadian, Y, Savvides, S.N, Gutsche, I, Loewith, R. Deposit date: 2021-09-17 Release date: 2023-01-18 Last modified: 2023-03-29 Method: ELECTRON MICROSCOPY (3.87 Å) Cite: EGOC inhibits TOROID polymerization by structurally activating TORC1. Nat.Struct.Mol.Biol., 30, 2023

<1234