4BHF
| Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with 4-(Trimethylammonio)pentanoate | Descriptor: | 4-(Trimethylammonio)pentanoic acid, GAMMA-BUTYROBETAINE DIOXYGENASE, HEXANE-1,6-DIAMINE, ... | Authors: | Tars, K, Leitans, J, Kazaks, A. | Deposit date: | 2013-04-02 | Release date: | 2014-03-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase. J.Med.Chem., 57, 2014
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1OIK
| Crystal structure of the alkylsulfatase AtsK, a non-heme Fe(II) alphaketoglutarate dependent Dioxygenase in complex with fe, alphaketoglutarate and 2-ethyl-1-hexanesulfuric acid | Descriptor: | (2R)-2-ETHYL-1-HEXANESULFONIC ACID, 2-OXOGLUTARIC ACID, FE (II) ION, ... | Authors: | Mueller, I, Kahnert, A, Pape, T, Dierks, T, Meyer-Klauke, W, Kertesz, M.A, Uson, I. | Deposit date: | 2003-06-18 | Release date: | 2004-03-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Crystal Structure of the Alkylsulfatase Atsk: Insights Into the Catalytic Mechanism of the Fe(II) Alpha-Ketoglutarate-Dependent Dioxygenase Superfamily Biochemistry, 42, 2004
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4M2E
| Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-homoarginine | Descriptor: | FE (III) ION, L-HOMOARGININE, L-arginine beta-hydroxylase | Authors: | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | Deposit date: | 2013-08-05 | Release date: | 2014-06-25 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.06 Å) | Cite: | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms. Angew.Chem.Int.Ed.Engl., 53, 2014
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1DRT
| CRYSTAL STRUCTURE OF CLAVAMINATE SYNTHASE IN COMPLEX WITH FE(II), 2-OXOGLUTARATE AND PROCLAVAMINIC ACID | Descriptor: | 2-OXOGLUTARIC ACID, 5-AMINO-3-HYDROXY-2-(2-OXO-AZETIDIN-1-YL)-PENTANOIC ACID, CLAVAMINATE SYNTHASE 1, ... | Authors: | Zhang, Z.H, Ren, J, Stammers, D.K, Baldwin, J.E, Harlos, K, Schofield, C.J. | Deposit date: | 2000-01-06 | Release date: | 2000-07-06 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural origins of the selectivity of the trifunctional oxygenase clavaminic acid synthase. Nat.Struct.Biol., 7, 2000
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1OIJ
| Crystal structure of the alkylsulfatase AtsK, a non-heme Fe(II) alphaketoglutarate dependent Dioxygenase in complex with alphaketoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, PUTATIVE ALKYLSULFATASE ATSK, SODIUM ION | Authors: | Mueller, I, Kahnert, A, Pape, T, Dierks, T, Meyer-Klauke, W, Kertesz, M.A, Uson, I. | Deposit date: | 2003-06-18 | Release date: | 2004-03-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Crystal Structure of the Alkylsulfatase Atsk: Insights Into the Catalytic Mechanism of the Fe(II) Alpha-Ketoglutarate-Dependent Dioxygenase Superfamily Biochemistry, 42, 2004
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6DAW
| X-ray crystal structure of NapI L-arginine desaturase bound to Fe(II), L-arginine, and acetate | Descriptor: | ACETATE ION, ARGININE, FE (II) ION, ... | Authors: | Mitchell, A.J, Dunham, N.P, Boal, A.K. | Deposit date: | 2018-05-02 | Release date: | 2018-05-16 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Two Distinct Mechanisms for C-C Desaturation by Iron(II)- and 2-(Oxo)glutarate-Dependent Oxygenases: Importance of alpha-Heteroatom Assistance. J. Am. Chem. Soc., 140, 2018
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6XPA
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4OJ8
| Crystal structure of carbapenem synthase in complex with (3S,5S)-carbapenam | Descriptor: | (2S,5S)-7-oxo-1-azabicyclo[3.2.0]heptane-2-carboxylic acid, (5R)-carbapenem-3-carboxylate synthase, 2-OXOGLUTARIC ACID, ... | Authors: | Boal, A.K, Rosenzweig, A.C. | Deposit date: | 2014-01-20 | Release date: | 2014-04-02 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Mechanism of the C5 stereoinversion reaction in the biosynthesis of carbapenem antibiotics. Science, 343, 2014
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5VN6
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8KIF
| The structure of MmaE with substrate | Descriptor: | (3R)-3-(2-hydroxy-2-oxoethylamino)decanoic acid, FE (II) ION, Putative dioxygenase | Authors: | Chen, J, Zhou, J. | Deposit date: | 2023-08-23 | Release date: | 2024-04-17 | Method: | X-RAY DIFFRACTION (2.13 Å) | Cite: | Variation in Biosynthesis and Metal-Binding Properties of Isonitrile-Containing Peptides Produced by Mycobacteria versus Streptomyces Acs Catalysis, 14, 2024
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1VZ5
| Succinate Complex of AtsK | Descriptor: | PUTATIVE ALKYLSULFATASE ATSK, SUCCINIC ACID | Authors: | Mueller, I, Stueckl, A.C, Uson, I, Kertesz, M. | Deposit date: | 2004-05-14 | Release date: | 2004-11-15 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Succinate Complex Crystal Structures of the Alpha-Ketoglutarate-Dependent Dioxygenase Atsk: Steric Aspects of Enzyme Self-Hydroxylation J.Biol.Chem., 280, 2005
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5BKE
| Crystal structure of AAD-2 in complex with Mn(II) and N-oxalylglycine | Descriptor: | Alpha-ketoglutarate-dependent 2,4-dichlorophenoxyacetate dioxygenase, MANGANESE (II) ION, N-OXALYLGLYCINE, ... | Authors: | Chekan, J.R, Nair, S.K. | Deposit date: | 2019-06-02 | Release date: | 2019-06-12 | Last modified: | 2023-09-27 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Molecular basis for enantioselective herbicide degradation imparted by aryloxyalkanoate dioxygenases in transgenic plants. Proc.Natl.Acad.Sci.USA, 116, 2019
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4BHI
| Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with 3-(1,1,1,2-Tetramethylhydrazin-1-ium-2-yl)propanoate | Descriptor: | 3-(1,1,1,2-TETRAMETHYLHYDRAZIN-1-IUM-2-YL)PROPANOATE, GAMMA-BUTYROBETAINE DIOXYGENASE, HEXANE-1,6-DIAMINE, ... | Authors: | Tars, K, Leitans, J, Kazaks, A. | Deposit date: | 2013-04-03 | Release date: | 2014-03-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase. J.Med.Chem., 57, 2014
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6L6W
| The structure of ScoE with intermediate | Descriptor: | (3R)-3-[[(1R)-1,2-bis(oxidanyl)-2-oxidanylidene-ethyl]amino]butanoic acid, FE (II) ION, FORMIC ACID, ... | Authors: | Chen, T.Y, Chen, J, Zhou, J, Chang, W. | Deposit date: | 2019-10-29 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Pathway from N-Alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases. Angew.Chem.Int.Ed.Engl., 59, 2020
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4NE0
| Crystal structure of non-heme iron oxygenase OrfP D157A mutant in complex with (3S)-hydroxy-L-Arg | Descriptor: | (2S,3S)-3-HYDROXYARGININE, FE (III) ION, L-arginine beta-hydroxylase, ... | Authors: | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | Deposit date: | 2013-10-28 | Release date: | 2014-06-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.17 Å) | Cite: | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms Angew.Chem.Int.Ed.Engl., 53, 2014
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6L6X
| The structure of ScoE with substrate | Descriptor: | (3~{R})-3-(2-hydroxy-2-oxoethylamino)butanoic acid, D(-)-TARTARIC ACID, FE (II) ION, ... | Authors: | Chen, T.Y, Chen, J, Zhou, J, Chang, W. | Deposit date: | 2019-10-29 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Pathway from N-Alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases. Angew.Chem.Int.Ed.Engl., 59, 2020
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4BGK
| Three dimensional structure of human gamma-butyrobetaine hydroxylase in complex with (3-(Trimethylammonio)propyl)phosphinate | Descriptor: | GAMMA-BUTYROBETAINE DIOXYGENASE, HEXANE-1,6-DIAMINE, N-OXALYLGLYCINE, ... | Authors: | Tars, K, Leitans, J, Kazaks, A. | Deposit date: | 2013-03-27 | Release date: | 2014-03-12 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.18 Å) | Cite: | Targeting Carnitine Biosynthesis: Discovery of New Inhibitors Against Gamma-Butyrobetaine Hydroxylase. J.Med.Chem., 57, 2014
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1OII
| Crystal structure of the alkylsulfatase AtsK, a non-heme Fe(II) alphaketoglutarate dependent Dioxygenase in complex with iron and alphaketoglutarate | Descriptor: | 2-OXOGLUTARIC ACID, FE (II) ION, PUTATIVE ALKYLSULFATASE ATSK | Authors: | Mueller, I, Kahnert, A, Pape, T, Dierks, T, Meyer-Klauke, W, Kertesz, M.A, Uson, I. | Deposit date: | 2003-06-18 | Release date: | 2004-03-30 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2.19 Å) | Cite: | Crystal Structure of the Alkylsulfatase Atsk: Insights Into the Catalytic Mechanism of the Fe(II) Alpha-Ketoglutarate-Dependent Dioxygenase Superfamily Biochemistry, 42, 2004
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6L86
| The structure of SfaA | Descriptor: | (2S)-2-hydroxybutanedioic acid, D-MALATE, FE (II) ION, ... | Authors: | Chen, T.Y, Chen, J, Zhou, J, Chang, W. | Deposit date: | 2019-11-05 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.23 Å) | Cite: | Pathway from N-Alkylglycine to Alkylisonitrile Catalyzed by Iron(II) and 2-Oxoglutarate-Dependent Oxygenases. Angew.Chem.Int.Ed.Engl., 59, 2020
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5EQN
| Structure of phosphonate hydroxylase | Descriptor: | FrbJ, MAGNESIUM ION | Authors: | Li, C, Hu, Y, Zhang, H. | Deposit date: | 2015-11-13 | Release date: | 2016-05-18 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structural analysis of a phosphonate hydroxylase with an access tunnel at the back of the active site. Acta Crystallogr.,Sect.F, 72, 2016
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6D0O
| rdpA dioxygenase holoenzyme | Descriptor: | (R)-phenoxypropionate/alpha-ketoglutarate-dioxygenase, 2-OXOGLUTARIC ACID, COBALT (II) ION | Authors: | Rydel, T.J, Sturman, E.J, Zheng, M, Evdokimov, A. | Deposit date: | 2018-04-10 | Release date: | 2018-08-15 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Development of enzymes for robust aryloxyphenoxypropionate and synthetic auxin herbicide tolerance traits in maize and soybean crops. Pest Manag. Sci., 75, 2019
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1NX8
| Structure of carbapenem synthase (CarC) complexed with N-acetyl proline | Descriptor: | 1-ACETYL-L-PROLINE, 2-OXOGLUTARIC ACID, Carbapenem synthase, ... | Authors: | Clifton, I.J, Doan, L.X, Sleeman, M.C, Topf, M, Suzuki, H, Wilmouth, R.C, Schofield, C.J. | Deposit date: | 2003-02-10 | Release date: | 2003-06-17 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Crystal structure of carbapenem synthase (CarC). J.Biol.Chem., 278, 2003
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4M27
| Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and L-Arg | Descriptor: | ARGININE, FE (III) ION, L-arginine beta-hydroxylase, ... | Authors: | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | Deposit date: | 2013-08-05 | Release date: | 2014-06-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms. Angew.Chem.Int.Ed.Engl., 53, 2014
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4M2C
| Crystal structure of non-heme iron oxygenase OrfP in complex with Fe and D-Arg | Descriptor: | D-ARGININE, FE (III) ION, L-arginine beta-hydroxylase | Authors: | Chang, C.Y, Liu, Y.C, Lyu, S.Y, Wu, C.C, Li, T.L. | Deposit date: | 2013-08-05 | Release date: | 2014-06-25 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Biosynthesis of streptolidine involved two unexpected intermediates produced by a dihydroxylase and a cyclase through unusual mechanisms. Angew.Chem.Int.Ed.Engl., 53, 2014
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2Q4A
| Ensemble refinement of the protein crystal structure of gene product from Arabidopsis thaliana At3g21360 | Descriptor: | Clavaminate synthase-like protein At3g21360, FE (III) ION, SULFATE ION | Authors: | Levin, E.J, Kondrashov, D.A, Wesenberg, G.E, Phillips Jr, G.N, Center for Eukaryotic Structural Genomics (CESG) | Deposit date: | 2007-05-31 | Release date: | 2007-06-19 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Ensemble refinement of protein crystal structures: validation and application. Structure, 15, 2007
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