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3KOW
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BU of 3kow by Molmil
Crystal Structure of ornithine 4,5 aminomutase backsoaked complex
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, D-ornithine aminomutase E component, ...
著者Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D.
登録日2009-11-14
公開日2010-01-26
最終更新日2012-10-24
実験手法X-RAY DIFFRACTION (2.9 Å)
主引用文献Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase.
J.Biol.Chem., 285, 2010
3KOX
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BU of 3kox by Molmil
Crystal Structure of ornithine 4,5 aminomutase in complex with 2,4-diaminobutyrate (Anaerobic)
分子名称: (2S)-2-amino-4-{[(1Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}butanoic acid, 5'-DEOXYADENOSINE, COBALAMIN, ...
著者Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D.
登録日2009-11-14
公開日2010-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.4 Å)
主引用文献Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase.
J.Biol.Chem., 285, 2010
3KOY
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BU of 3koy by Molmil
Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Aerobic)
分子名称: (E)-N~5~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-ornithine, 5'-DEOXYADENOSINE, COBALAMIN, ...
著者Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D.
登録日2009-11-14
公開日2010-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase.
J.Biol.Chem., 285, 2010
3KOZ
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BU of 3koz by Molmil
Crystal Structure of ornithine 4,5 aminomutase in complex with ornithine (Anaerobic)
分子名称: (E)-N~5~-({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene)-L-ornithine, 5'-DEOXYADENOSINE, COBALAMIN, ...
著者Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D.
登録日2009-11-14
公開日2010-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase.
J.Biol.Chem., 285, 2010
3KP0
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BU of 3kp0 by Molmil
Crystal Structure of ORNITHINE 4,5 AMINOMUTASE in complex with 2,4-diaminobutyrate (DAB) (Aerobic)
分子名称: (2S)-2-amino-4-{[(1Z)-{3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methylidene]amino}butanoic acid, 5'-DEOXYADENOSINE, COBALAMIN, ...
著者Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D.
登録日2009-11-14
公開日2010-01-26
最終更新日2024-02-21
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase.
J.Biol.Chem., 285, 2010
3KP1
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BU of 3kp1 by Molmil
Crystal structure of ornithine 4,5 aminomutase (Resting State)
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, D-ornithine aminomutase E component, ...
著者Wolthers, K.R, Levy, C.W, Scrutton, N.S, Leys, D.
登録日2009-11-14
公開日2010-01-26
最終更新日2019-10-30
実験手法X-RAY DIFFRACTION (2.01 Å)
主引用文献Large-scale domain dynamics and adenosylcobalamin reorientation orchestrate radical catalysis in ornithine 4,5-aminomutase.
J.Biol.Chem., 285, 2010
3REQ
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BU of 3req by Molmil
METHYLMALONYL-COA MUTASE, SUBSTRATE-FREE STATE (POOR QUALITY STRUCTURE)
分子名称: ADENOSINE, COBALAMIN, METHYLMALONYL-COA MUTASE
著者Evans, P.R, Mancia, F.
登録日1997-12-04
公開日1998-03-18
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.7 Å)
主引用文献Conformational changes on substrate binding to methylmalonyl CoA mutase and new insights into the free radical mechanism.
Structure, 6, 1998
4JGI
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BU of 4jgi by Molmil
1.5 Angstrom crystal structure of a novel cobalamin-binding protein from Desulfitobacterium hafniense DCB-2
分子名称: CO-METHYLCOBALAMIN, Putative uncharacterized protein
著者Sjuts, H, Dunstan, M.S, Fisher, K, Leys, D.
登録日2013-03-01
公開日2013-08-07
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Structure of the cobalamin-binding protein of a putative O-demethylase from Desulfitobacterium hafniense DCB-2.
Acta Crystallogr.,Sect.D, 69, 2013
4Q37
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BU of 4q37 by Molmil
Crystal structure of the hypothetical protein TM0182 Thermotoga maritima, N-terminal domain.
分子名称: PLATINUM (II) ION, Radical SAM protein
著者Hocker, B, Farias-Rico, J.A.
登録日2014-04-11
公開日2014-07-16
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.19 Å)
主引用文献Evolutionary relationship of two ancient protein superfolds.
Nat.Chem.Biol., 10, 2014
4R3U
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BU of 4r3u by Molmil
Crystal structure of 2-Hydroxyisobutyryl-CoA Mutase
分子名称: 2-hydroxyisobutyryl-CoA mutase large subunit, 2-hydroxyisobutyryl-CoA mutase small subunit, 3-HYDROXYBUTANOYL-COENZYME A, ...
著者Zahn, M, Kurteva-Yaneva, N, Rohwerder, T, Straeter, N.
登録日2014-08-18
公開日2015-03-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (2.5 Å)
主引用文献Structural basis of the stereospecificity of bacterial B12-dependent 2-hydroxyisobutyryl-CoA mutase.
J.Biol.Chem., 290, 2015
4REQ
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BU of 4req by Molmil
Methylmalonyl-COA Mutase substrate complex
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, GLYCEROL, ...
著者Evans, P.R, Mancia, F.
登録日1998-06-17
公開日1999-01-13
最終更新日2024-05-22
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Conformational changes on substrate binding to methylmalonyl CoA mutase and new insights into the free radical mechanism.
Structure, 6, 1998
4XC6
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BU of 4xc6 by Molmil
Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, and Mg (holo-IcmF/GDP)
分子名称: 5'-DEOXYADENOSINE, ACETATE ION, COBALAMIN, ...
著者Jost, M, Drennan, C.L.
登録日2014-12-17
公開日2015-02-11
最終更新日2024-02-28
実験手法X-RAY DIFFRACTION (3.35 Å)
主引用文献Visualization of a radical B12 enzyme with its G-protein chaperone.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XC7
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BU of 4xc7 by Molmil
Isobutyryl-CoA mutase fused with bound butyryl-CoA and without cobalamin or GDP (apo-IcmF)
分子名称: Butyryl Coenzyme A, Isobutyryl-CoA mutase fused, L(+)-TARTARIC ACID
著者Jost, M, Drennan, C.L.
登録日2014-12-17
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Visualization of a radical B12 enzyme with its G-protein chaperone.
Proc.Natl.Acad.Sci.USA, 112, 2015
4XC8
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BU of 4xc8 by Molmil
Isobutyryl-CoA mutase fused with bound butyryl-CoA, GDP, and Mg and without cobalamin (apo-IcmF/GDP)
分子名称: Butyryl Coenzyme A, GUANOSINE-5'-DIPHOSPHATE, Isobutyryl-CoA mutase fused, ...
著者Jost, M, Drennan, C.L.
登録日2014-12-17
公開日2015-02-11
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.25 Å)
主引用文献Visualization of a radical B12 enzyme with its G-protein chaperone.
Proc.Natl.Acad.Sci.USA, 112, 2015
5CJT
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BU of 5cjt by Molmil
Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate isobutyryl-coenzyme A
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jost, M, Drennan, C.L.
登録日2015-07-15
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases.
J.Biol.Chem., 290, 2015
5CJU
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BU of 5cju by Molmil
Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate n-butyryl-coenzyme A
分子名称: 5'-DEOXYADENOSINE, Butyryl Coenzyme A, COBALAMIN, ...
著者Jost, M, Drennan, C.L.
登録日2015-07-15
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.5 Å)
主引用文献Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases.
J.Biol.Chem., 290, 2015
5CJV
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BU of 5cjv by Molmil
Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate isovaleryl-coenzyme A
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jost, M, Drennan, C.L.
登録日2015-07-15
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.45 Å)
主引用文献Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases.
J.Biol.Chem., 290, 2015
5CJW
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BU of 5cjw by Molmil
Isobutyryl-CoA mutase fused with bound adenosylcobalamin, GDP, Mg (holo-IcmF/GDP), and substrate pivalyl-coenzyme A
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, GUANOSINE-5'-DIPHOSPHATE, ...
著者Jost, M, Drennan, C.L.
登録日2015-07-15
公開日2015-09-09
最終更新日2023-09-27
実験手法X-RAY DIFFRACTION (3.4 Å)
主引用文献Structural Basis for Substrate Specificity in Adenosylcobalamin-dependent Isobutyryl-CoA Mutase and Related Acyl-CoA Mutases.
J.Biol.Chem., 290, 2015
5REQ
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BU of 5req by Molmil
Methylmalonyl-COA MUTASE, Y89F Mutant, substrate complex
分子名称: COBALAMIN, GLYCEROL, METHYLMALONYL(CARBADETHIA)-COENZYME A, ...
著者Evans, P.R, Thomae, N.H.
登録日1998-08-03
公開日1998-08-12
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Stabilization of radical intermediates by an active-site tyrosine residue in methylmalonyl-CoA mutase.
Biochemistry, 37, 1998
6H9E
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BU of 6h9e by Molmil
Structure of glutamate mutase reconstituted with homo-coenzyme B12
分子名称: (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-ethyl-oxolane-3,4-diol, COBALAMIN, D(-)-TARTARIC ACID, ...
著者Gruber, K, Csitkovits, V, Kratky, C.
登録日2018-08-03
公開日2019-08-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (1.82 Å)
主引用文献Structure-Based Demystification of Radical Catalysis by a Coenzyme B 12 Dependent Enzyme-Crystallographic Study of Glutamate Mutase with Cofactor Homologues.
Angew.Chem.Int.Ed.Engl., 61, 2022
6H9F
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BU of 6h9f by Molmil
Structure of glutamate mutase reconstituted with bishomo-coenzyme B12
分子名称: (2~{R},3~{R},4~{S},5~{R})-2-(6-aminopurin-9-yl)-5-propyl-oxolane-3,4-diol, COBALAMIN, D(-)-TARTARIC ACID, ...
著者Gruber, K, Csitkovits, V, Kratky, C.
登録日2018-08-03
公開日2019-08-14
最終更新日2024-01-31
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Structure-Based Demystification of Radical Catalysis by a Coenzyme B 12 Dependent Enzyme-Crystallographic Study of Glutamate Mutase with Cofactor Homologues.
Angew.Chem.Int.Ed.Engl., 61, 2022
6OXC
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BU of 6oxc by Molmil
Structure of Mycobacterium tuberculosis methylmalonyl-CoA mutase with adenosyl cobalamin
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, Methylmalonyl-CoA mutase large subunit, ...
著者Purchal, M, Ruetz, M, Banerjee, R, Koutmos, M.
登録日2019-05-13
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair.
Science, 366, 2019
6OXD
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BU of 6oxd by Molmil
Structure of Mycobacterium tuberculosis methylmalonyl-CoA mutase with adenosyl cobalamin
分子名称: 5'-DEOXYADENOSINE, COBALAMIN, Itaconyl coenzyme A, ...
著者Purchal, M, Ruetz, M, Banerjee, R, Koutmos, M.
登録日2019-05-13
公開日2019-11-13
最終更新日2023-10-11
実験手法X-RAY DIFFRACTION (2 Å)
主引用文献Itaconyl-CoA forms a stable biradical in methylmalonyl-CoA mutase and derails its activity and repair.
Science, 366, 2019
6REQ
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BU of 6req by Molmil
METHYLMALONYL-COA MUTASE, 3-CARBOXYPROPYL-COA INHIBITOR COMPLEX
分子名称: 3-CARBOXYPROPYL-COENZYME A, COBALAMIN, GLYCEROL, ...
著者Evans, P.R, Mancia, F.
登録日1998-09-03
公開日1999-09-09
最終更新日2023-09-20
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Crystal structure of substrate complexes of methylmalonyl-CoA mutase.
Biochemistry, 38, 1999
6WTE
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BU of 6wte by Molmil
Structure of radical S-adenosylmethionine methyltransferase, TsrM, from Kitasatospora setae with cobalamin and [4Fe-4S] cluster bound
分子名称: 1,2-ETHANEDIOL, B12-binding domain-containing protein, COBALAMIN, ...
著者Knox, H.L, Chen, P.Y.-T, Drennan, C.L, Booker, S.J.
登録日2020-05-02
公開日2020-12-23
最終更新日2024-03-06
実験手法X-RAY DIFFRACTION (1.67 Å)
主引用文献Structural basis for non-radical catalysis by TsrM, a radical SAM methylase.
Nat.Chem.Biol., 17, 2021

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