PDB: 41 件ウェブページステータス検索Chemie searchBIRD

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3ZM9	The mechanism of allosteric coupling in choline kinase a1 revealed by a rationally designed inhibitor 分子名称: 1-(4-(4-(4-((6-amino-9H-purin-9-yl)methyl)phenyl)butyl)benzyl)-4- (dimethylamino)pyridinium, CHOLINE KINASE ALPHA 著者 Sahun-Roncero, M, Rubio-Ruiz, B, Saladino, G, Conejo-Garcia, A, Espinosa, A, Velazquez-Campoy, A, Gervasio, F.L, Entrena, A, Hurtado-Guerrero, R. 登録日 2013-02-06 公開日 2013-02-27 最終更新日 2023-12-20 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 The Mechanism of Allosteric Coupling in Choline Kinase A1 Revealed by a Rationally Designed Inhibitor Angew.Chem.Int.Ed.Engl., 52, 2013
3LQ3	Crystal structure of human choline kinase beta in complex with phosphorylated hemicholinium-3 and adenosine nucleotide 分子名称: (2S)-2-[4'-({dimethyl[2-(phosphonooxy)ethyl]ammonio}acetyl)biphenyl-4-yl]-2-hydroxy-4,4-dimethylmorpholin-4-ium, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Hong, B.S, Tempel, W, Rabeh, W.M, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H.W, Structural Genomics Consortium (SGC) 登録日 2010-02-08 公開日 2010-05-05 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.42 Å) 主引用文献 Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity. J.Biol.Chem., 285, 2010
3MES	Crystal structure of choline kinase from Cryptosporidium parvum Iowa II, cgd3_2030 分子名称: ADENOSINE-5'-DIPHOSPHATE, Choline kinase, DECAMETHONIUM ION, ... 著者 Qiu, W, Wernimont, A, Hills, T, Lew, J, Artz, J.D, Xiao, T, Allali-Hassani, A, Vedadi, M, Kozieradzki, I, Cossar, D, Bountra, C, Weigelt, J, Arrowsmith, C.H, Edwards, A.M, Hui, R, Ma, D, Structural Genomics Consortium (SGC) 登録日 2010-03-31 公開日 2010-04-07 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure of choline kinase from Cryptosporidium parvum Iowa II, cgd3_2030 TO BE PUBLISHED
3FI8	Crystal structure of choline kinase from Plasmodium Falciparum, PF14_0020 分子名称: ADENOSINE-5'-DIPHOSPHATE, Choline kinase, MAGNESIUM ION, ... 著者 Wernimont, A.K, Pizarro, J.C, Artz, J.D, Amaya, M.F, Xiao, T, Lew, J, Wasney, G, Senesterra, G, Kozieradzki, I, Cossar, D, Vedadi, M, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Hills, T, Structural Genomics Consortium (SGC) 登録日 2008-12-11 公開日 2009-02-10 最終更新日 2024-02-21 実験手法 X-RAY DIFFRACTION (2.3 Å) 主引用文献 Crystal structure of choline kinase from Plasmodium Falciparum, PF14_0020 TO BE PUBLISHED
3G15	Crystal structure of human choline kinase alpha in complex with hemicholinium-3 and ADP 分子名称: (2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium), ADENOSINE-5'-DIPHOSPHATE, Choline kinase alpha, ... 著者 Hong, B.S, Tempel, W, Rabeh, W.M, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H.W, Structural Genomics Consortium (SGC) 登録日 2009-01-29 公開日 2009-02-10 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.7 Å) 主引用文献 Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity. J.Biol.Chem., 285, 2010
3FEG	Crystal structure of human choline kinase beta in complex with phosphorylated hemicholinium-3 and adenosine nucleotide 分子名称: (2S)-2-[4'-({dimethyl[2-(phosphonooxy)ethyl]ammonio}acetyl)biphenyl-4-yl]-2-hydroxy-4,4-dimethylmorpholin-4-ium, ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ... 著者 Hong, B.S, Tempel, W, Rabeh, W.M, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H.W, Structural Genomics Consortium (SGC) 登録日 2008-11-29 公開日 2008-12-23 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (1.302 Å) 主引用文献 Crystal structures of human choline kinase isoforms in complex with hemicholinium-3: single amino acid near the active site influences inhibitor sensitivity. J.Biol.Chem., 285, 2010
3F2R	Crystal structure of human choline kinase alpha in complex with hemicholinium-3 分子名称: (2S,2'S)-2,2'-biphenyl-4,4'-diylbis(2-hydroxy-4,4-dimethylmorpholin-4-ium), Choline kinase alpha, UNKNOWN ATOM OR ION 著者 Hong, B, Tempel, W, Rabeh, W.M, MacKenzie, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2008-10-30 公開日 2008-11-11 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (2.35 Å) 主引用文献 Crystal structure of human choline kinase alpha in complex with hemicholinium-3 To be Published
3DXQ	Crystal structure of choline/ethanolamine kinase family protein (NP_106042.1) from MESORHIZOBIUM LOTI at 2.55 A resolution 分子名称: choline/ethanolamine kinase family protein 著者 Joint Center for Structural Genomics (JCSG) 登録日 2008-07-24 公開日 2008-08-05 最終更新日 2023-02-01 実験手法 X-RAY DIFFRACTION (2.55 Å) 主引用文献 Crystal structure of choline/ethanolamine kinase family protein (NP_106042.1) from MESORHIZOBIUM LOTI at 2.55 A resolution To be published
3C5I	Crystal structure of Plasmodium knowlesi choline kinase, PKH_134520 分子名称: CALCIUM ION, CHOLINE ION, Choline kinase, ... 著者 Wernimont, A.K, Hills, T, Lew, J, Wasney, G, Senesterra, G, Kozieradzki, I, Cossar, D, Vedadi, M, Schapira, M, Bochkarev, A, Arrowsmith, C.H, Bountra, C, Weigelt, J, Edwards, A.M, Hui, R, Artz, J.D, Xiao, T, Structural Genomics Consortium (SGC) 登録日 2008-01-31 公開日 2008-02-19 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.2 Å) 主引用文献 Crystal structure of Plasmodium knowlesi choline kinase, PKH_134520. To be Published
2QG7	Plasmodium vivax ethanolamine kinase Pv091845 分子名称: SULFATE ION, ethanolamine kinase Pv091845 著者 Lunin, V.V, Wernimont, A.K, Mulichak, A, Lew, J, Wasney, G, Senisterra, G, Kozieradzki, I, Vedadi, M, Bochkarev, A, Arrowsmith, C.H, Sundstrom, M, Weigelt, J, Edwards, A.E, Hui, R, Hills, T, Artz, J, Xiao, T, Structural Genomics Consortium (SGC) 登録日 2007-06-28 公開日 2007-07-24 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (2.407 Å) 主引用文献 Plasmodium vivax ethanolamine kinase Pv091845 TO BE PUBLISHED
2IG7	Crystal structure of Human Choline Kinase B 分子名称: Choline/ethanolamine kinase, UNKNOWN ATOM OR ION 著者 Rabeh, W.M, Tempel, W, Nedyalkova, L, Wasney, G, Landry, R, Vedadi, M, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2006-09-22 公開日 2006-10-10 最終更新日 2017-10-18 実験手法 X-RAY DIFFRACTION (1.8 Å) 主引用文献 Crystal structure of Human Choline Kinase B To be Published
2CKO	Crystal structure of Human Choline Kinase alpha 2 分子名称: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, CHOLINE KINASE ALPHA 著者 Malito, E, Lavie, A. 登録日 2006-04-20 公開日 2006-10-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.15 Å) 主引用文献 Elucidation of Human Choline Kinase Crystal Structures in Complex with the Products Adp or Phosphocholine. J.Mol.Biol., 364, 2006
2CKP	Crystal structure of Human Choline Kinase alpha-2 in complex with ADP 分子名称: ADENOSINE-5'-DIPHOSPHATE, CHOLINE KINASE ALPHA 著者 Malito, E, Lavie, A. 登録日 2006-04-20 公開日 2006-10-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (3.1 Å) 主引用文献 Elucidation of Human Choline Kinase Crystal Structures in Complex with the Products Adp or Phosphocholine. J.Mol.Biol., 364, 2006
2CKQ	Crystal structure of Human Choline Kinase alpha 2 in complex with Phosphocholine 分子名称: CHOLINE KINASE ALPHA, PHOSPHOCHOLINE 著者 Malito, E, Lavie, A. 登録日 2006-04-20 公開日 2006-10-04 最終更新日 2023-12-13 実験手法 X-RAY DIFFRACTION (2.4 Å) 主引用文献 Elucidation of Human Choline Kinase Crystal Structures in Complex with the Products Adp or Phosphocholine. J.Mol.Biol., 364, 2006
2I7Q	Crystal structure of Human Choline Kinase A 分子名称: CHLORIDE ION, Choline kinase alpha, UNKNOWN ATOM OR ION 著者 Rabeh, W.M, Tempel, W, Nedyalkova, L, Wasney, G, Landry, R, Arrowsmith, C.H, Edwards, A.M, Sundstrom, M, Weigelt, J, Bochkarev, A, Park, H, Structural Genomics Consortium (SGC) 登録日 2006-08-31 公開日 2006-09-12 最終更新日 2023-08-30 実験手法 X-RAY DIFFRACTION (1.9 Å) 主引用文献 Crystal structure of Human Choline Kinase A To be Published
1NW1	Crystal Structure of Choline Kinase 分子名称: CALCIUM ION, Choline kinase (49.2 kD) 著者 Peisach, D, Gee, P, Kent, C, Xu, Z. 登録日 2003-02-05 公開日 2003-06-10 最終更新日 2024-02-14 実験手法 X-RAY DIFFRACTION (2.02 Å) 主引用文献 The Crystal Structure of Choline Kinase Reveals a Eukaryotic Protein Kinase Fold Structure, 11, 2003

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