PDB: 195 resultsInfo pagesStatus searchChemie searchBIRD

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3ZKC	Crystal structure of the master regulator for biofilm formation SinR in complex with DNA. Descriptor: 5'-D(*AP*AP*AP*GP*TP*TP*CP*TP*CP*TP*TP*TP*AP*GP *AP*GP*AP*AP*CP*AP*AP)-3', 5'-D(*AP*TP*TP*GP*TP*TP*CP*TP*CP*TP*AP*AP*AP*GP *AP*GP*AP*AP*CP*TP*TP)-3', HTH-TYPE TRANSCRIPTIONAL REGULATOR SINR Authors: Newman, J.A, Rodrigues, C, Lewis, R.J. Deposit date: 2013-01-22 Release date: 2013-03-06 Last modified: 2023-12-20 Method: X-RAY DIFFRACTION (3 Å) Cite: Molecular Basis of the Activity of Sinr, the Master Regulator of Biofilm Formation in Bacillus Subtilis. J.Biol.Chem., 288, 2013
1B0N	SINR PROTEIN/SINI PROTEIN COMPLEX Descriptor: PROTEIN (SINI PROTEIN), PROTEIN (SINR PROTEIN), ZINC ION Authors: Lewis, R.J, Brannigan, J.A, Offen, W.A, Smith, I, Wilkinson, A.J. Deposit date: 1998-11-11 Release date: 1999-01-13 Last modified: 2023-12-27 Method: X-RAY DIFFRACTION (1.9 Å) Cite: An evolutionary link between sporulation and prophage induction in the structure of a repressor:anti-repressor complex. J.Mol.Biol., 283, 1998
6W1A	Crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2 bound to DNA Descriptor: DNA (30-MER), GLYCEROL, PHOSPHATE ION, ... Authors: Capodagli, G.C, Neiditch, M.B. Deposit date: 2020-03-03 Release date: 2020-10-21 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure-function studies of Rgg binding to pheromones and target promoters reveal a model of transcription factor interplay. Proc.Natl.Acad.Sci.USA, 117, 2020
7ZCV	Rgg144 of Streptococcus pneumoniae Descriptor: Transcriptional regulator Authors: Wallis, R, Girija, U.V, Yesilkaya, H. Deposit date: 2022-03-29 Release date: 2022-06-01 Last modified: 2022-07-06 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Structure-function analysis for the development of peptide inhibitors for a Gram-positive quorum sensing system. Mol.Microbiol., 117, 2022
5IFG	Crystal structure of HigA-HigB complex from E. Coli Descriptor: Antitoxin HigA, mRNA interferase HigB Authors: Yang, J.S, Zhou, K, Gao, z.Q, Liu, Q.S, Dong, Y.H. Deposit date: 2016-02-26 Release date: 2017-03-01 Method: X-RAY DIFFRACTION (2.702 Å) Cite: Structural insight into the E. coli HigBA complex Biochem. Biophys. Res. Commun., 478, 2016
5JUB	Crystal structure of ComR from S.thermophilus in complex with DNA and its signalling peptide ComS. Descriptor: ComS, Transcriptional regulator, pComX-for, ... Authors: Talagas, A, Fontaine, L, Ledesma-Garcia, L, Li de la Sierra-Gallay, I, Hols, P, Nessler, S. Deposit date: 2016-05-10 Release date: 2016-10-26 Last modified: 2016-12-14 Method: X-RAY DIFFRACTION (2.57 Å) Cite: Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS. PLoS Pathog., 12, 2016
5JUF	Crystal structure of the apo form of ComR from S. thermophilus. Descriptor: SULFATE ION, Transcriptional regulator Authors: Talagas, A, Fontaine, L, Ledesma, L, Li de la Sierra-Gallay, I, Hols, P, Nessler, S. Deposit date: 2016-05-10 Release date: 2016-10-26 Last modified: 2016-12-14 Method: X-RAY DIFFRACTION (1.946 Å) Cite: Structural Insights into Streptococcal Competence Regulation by the Cell-to-Cell Communication System ComRS. PLoS Pathog., 12, 2016
7JVT	Crystal structure of a lambda-186 hybrid repressor Descriptor: OL1 bottom, OL1 top, Repressor protein CI Authors: Truong, J.Q, Bruning, J.B, Shearwin, K.E. Deposit date: 2020-08-23 Release date: 2021-09-08 Last modified: 2023-10-18 Method: X-RAY DIFFRACTION (3.16 Å) Cite: Crystal structure of a hybrid lambda-186 repressor To Be Published
6F8S	Toxin-Antitoxin complex GraTA Descriptor: DI(HYDROXYETHYL)ETHER, Putative Killer protein, SULFATE ION, ... Authors: Talavera, A, Loris, R. Deposit date: 2017-12-13 Release date: 2018-07-11 Last modified: 2019-03-13 Method: X-RAY DIFFRACTION (2.5 Å) Cite: A dual role in regulation and toxicity for the disordered N-terminus of the toxin GraT. Nat Commun, 10, 2019
5W4N	Crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2(C45S) Descriptor: DIMETHYL SULFOXIDE, GLYCEROL, Transcriptional regulator Authors: Neiditch, M.B, Khataokar, A.A, Capodagli, G.C. Deposit date: 2017-06-12 Release date: 2017-10-25 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.198 Å) Cite: Activating mutations in quorum-sensing regulator Rgg2 and its conformational flexibility in the absence of an intermolecular disulfide bond. J. Biol. Chem., 292, 2017
5W4M	Crystal structure of Streptococcus dysgalactiae SHP pheromone receptor Rgg2(C45S) Descriptor: CHLORIDE ION, DIMETHYL SULFOXIDE, GLYCEROL, ... Authors: Capodagli, G.C, Neiditch, M.B. Deposit date: 2017-06-12 Release date: 2017-10-25 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.388 Å) Cite: Activating mutations in quorum-sensing regulator Rgg2 and its conformational flexibility in the absence of an intermolecular disulfide bond. J. Biol. Chem., 292, 2017
6HPC	Crystal structure of the HicB antitoxin from E. coli Descriptor: Antitoxin HicB Authors: Manav, M.C, Brodersen, D.E. Deposit date: 2018-09-20 Release date: 2019-09-18 Last modified: 2019-11-13 Method: X-RAY DIFFRACTION (2.26 Å) Cite: The E. coli HicB Antitoxin Contains a Structurally Stable Helix-Turn-Helix DNA Binding Domain. Structure, 27, 2019
1Y9Q	Crystal Structure of HTH_3 family Transcriptional Regulator from Vibrio cholerae Descriptor: D-METHIONINE, ZINC ION, transcriptional regulator, ... Authors: Kumaran, D, Swaminathan, S, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) Deposit date: 2004-12-16 Release date: 2005-01-04 Last modified: 2021-02-03 Method: X-RAY DIFFRACTION (1.9 Å) Cite: Crystal Structure of HTH_3 family Transcriptional Regulator from Vibrio cholerae To be Published
6QER	Apo Form Of ComR From S. Thermophilus in space group C2 Descriptor: Transcriptional regulator Authors: Thuillier, J, Nessler, S. Deposit date: 2019-01-08 Release date: 2019-02-20 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.465 Å) Cite: Molecular dissection of pheromone selectivity in the competence signaling system ComRS of streptococci. Proc.Natl.Acad.Sci.USA, 117, 2020
2WIU	Mercury-modified bacterial persistence regulator hipBA Descriptor: CHLORIDE ION, HTH-TYPE TRANSCRIPTIONAL REGULATOR HIPB, MERCURY (II) ION, ... Authors: Evdokimov, A, Voznesensky, I, Fennell, K, Anderson, M, Smith, J.F, Fisher, D.A. Deposit date: 2009-05-17 Release date: 2009-07-28 Last modified: 2012-04-04 Method: X-RAY DIFFRACTION (2.35 Å) Cite: New Kinase Regulation Mechanism Found in Hipba: A Bacterial Persistence Switch. Acta Crystallogr.,Sect.D, 65, 2009
7AB5	Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT D233Q) Descriptor: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ... Authors: Baerentsen, R.L, Brodersen, D.E. Deposit date: 2020-09-06 Release date: 2022-01-12 Last modified: 2022-08-03 Method: X-RAY DIFFRACTION (2.9 Å) Cite: Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation Biorxiv, 2022
7AB3	Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT S57A) Descriptor: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ... Authors: Baerentsen, R.L, Brodersen, D.E. Deposit date: 2020-09-06 Release date: 2022-01-12 Last modified: 2024-01-31 Method: X-RAY DIFFRACTION (2.4 Å) Cite: Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation Biorxiv, 2022
7AB4	Crystal structure of the Escherichia coli toxin-antitoxin system HipBST (HipT S59A) Descriptor: Couple_hipA domain-containing protein, HipA_C domain-containing protein, Predicted transcriptional regulator, ... Authors: Baerentsen, R.L, Brodersen, D.E. Deposit date: 2020-09-06 Release date: 2022-01-12 Last modified: 2022-08-03 Method: X-RAY DIFFRACTION (3.34 Å) Cite: Structural basis for regulation of a tripartite toxin-antitoxin system by dual phosphorylation Biorxiv, 2022
6TRI	CI-MOR repressor-antirepressor complex of the temperate bacteriophage TP901-1 from Lactococcus lactis Descriptor: CI, MOR, SULFATE ION Authors: Rasmussen, K.K, Blackledge, M, Herrmann, T, Jensen, M.R, Lo Leggio, L. Deposit date: 2019-12-18 Release date: 2020-08-19 Last modified: 2024-01-24 Method: X-RAY DIFFRACTION (2.277 Å) Cite: Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage. Proc.Natl.Acad.Sci.USA, 117, 2020
5YCL	Crystal structure of HigBA complex from Shigella flexneri Descriptor: Antitoxin HigA, mRNA interferase HigB Authors: Youn, W.S, Seok, S.H, Seo, M.D. Deposit date: 2017-09-07 Release date: 2018-09-19 Last modified: 2019-09-04 Method: X-RAY DIFFRACTION (3.101 Å) Cite: Structural changes of antitoxin HigA from Shigella flexneri by binding of its cognate toxin HigB. Int.J.Biol.Macromol., 130, 2019
4MCT	P. vulgaris HIGBA structure, crystal form 1 Descriptor: Antidote protein, Killer protein Authors: Schureck, M.A, Maehigashi, T, Dunham, C.M. Deposit date: 2013-08-21 Release date: 2013-12-11 Last modified: 2017-11-15 Method: X-RAY DIFFRACTION (2.8 Å) Cite: Structure of the Proteus vulgaris HigB-(HigA)2-HigB Toxin-Antitoxin Complex. J.Biol.Chem., 289, 2014
4MCX	P. vulgaris HIGBA structure, crystal form 2 Descriptor: Antidote protein, Killer protein Authors: Schureck, M.A, Maehigashi, T, Dunham, C.M. Deposit date: 2013-08-21 Release date: 2013-12-11 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Structure of the Proteus vulgaris HigB-(HigA)2-HigB Toxin-Antitoxin Complex. J.Biol.Chem., 289, 2014
6AF4	Toxin-Antitoxin module from Streptococcus pneumoniae Descriptor: HigA antitoxin, HigB toxin Authors: Kang, S.M, Kim, D.H, Jin, C. Deposit date: 2018-08-08 Release date: 2019-08-14 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.65 Å) Cite: Toxin-Antitoxin module from Streptococcus pneumoniae To Be Published
6AF3	Toxin-Antitoxin module from Streptococcus pneumoniae Descriptor: HigA antitoxin, HigB toxin Authors: Kang, S.M, Kim, D.H, Jin, C. Deposit date: 2018-08-08 Release date: 2019-08-14 Method: X-RAY DIFFRACTION (2.803 Å) Cite: Toxin-Antitoxin module from Streptococcus pneumoniae To Be Published
3DNV	MDT Protein Descriptor: DNA (5'-D(*DAP*DCP*DTP*DAP*DTP*DCP*DCP*DCP*DCP*DTP*DTP*DAP*DAP*DGP*DGP*DGP*DGP*DAP*DTP*DAP*DG)-3'), HTH-type transcriptional regulator hipB, Protein hipA, ... Authors: schumacher, M.A. Deposit date: 2008-07-02 Release date: 2009-01-27 Last modified: 2023-04-05 Method: X-RAY DIFFRACTION (2.68 Å) Cite: Molecular mechanisms of HipA-mediated multidrug tolerance and its neutralization by HipB. Science, 323, 2009

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